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Protein
Submitted name:

cDNA FLJ59455, highly similar to Homo sapiens neuronal guanine nucleotide exchange factor (NGEF), mRNA

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ59455, highly similar to Homo sapiens neuronal guanine nucleotide exchange factor (NGEF), mRNAImported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

MaxQBiB4DDI2
PeptideAtlasiB4DDI2
PRIDEiB4DDI2

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliB4DDI2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 180DHInterPro annotationAdd BLAST180
Domaini212 – 324PHInterPro annotationAdd BLAST113
Domaini335 – 396SH3InterPro annotationAdd BLAST62

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili100 – 120Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, SH3 domainPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3523 Eukaryota
COG5422 LUCA
HOVERGENiHBG058673

Family and domain databases

CDDicd00160 RhoGEF, 1 hit
cd11939 SH3_ephexin1, 1 hit
Gene3Di1.20.900.10, 1 hit
2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR035899 DBL_dom_sf
IPR000219 DH-domain
IPR035635 Ephexin-1_SH3
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR036028 SH3-like_dom_sf
IPR001452 SH3_domain
PfamiView protein in Pfam
PF00169 PH, 1 hit
PF00621 RhoGEF, 1 hit
PF00018 SH3_1, 1 hit
SMARTiView protein in SMART
SM00233 PH, 1 hit
SM00325 RhoGEF, 1 hit
SM00326 SH3, 1 hit
SUPFAMiSSF48065 SSF48065, 1 hit
SSF50044 SSF50044, 1 hit
PROSITEiView protein in PROSITE
PS50010 DH_2, 1 hit
PS50003 PH_DOMAIN, 1 hit
PS50002 SH3, 1 hit

Sequencei

Sequence statusi: Complete.

B4DDI2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFELVTSEAS YYKSLNLLVS HFMENERIRK ILHPSEAHIL FSNVLDVLAV
60 70 80 90 100
SERFLLELEH RMEENIVISD VCDIVYRYAA DHFSVYITYV SNQTYQERTY
110 120 130 140 150
KQLLQEKAAF RELIAQLELD PKCRGLPFSS FLILPFQRIT RLKLLVQNIL
160 170 180 190 200
KRVEERSERE CTALDAHKEL EMVVKACNEG VRKMSRTEQM ISIQKKMEFK
210 220 230 240 250
IKSVPIISHS RWLLKQGELQ QMSGPKTSRT LRTKKLFHEI YLFLFNDLLV
260 270 280 290 300
ICRQIPGDKY QVFDSAPRGL LRVEELEDQG QTLANVFILR LLENADDREA
310 320 330 340 350
TYMLKASSQS EMKRWMTSLA PNRRTKFVSF TSRLLDCPQV QCVHPYVAQQ
360 370 380 390 400
PDELTLELAD ILNILDKTDD GWIFGERLHD QERGWFPSSM TEEILNPKIR
410 420 430
SQNLKECFRV HKMDDPQRSQ NKDRRKLGSR NRQ
Length:433
Mass (Da):50,970
Last modified:September 23, 2008 - v1
Checksum:i355240E0DE0E69DF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK293203 mRNA Translation: BAG56743.1
RefSeqiXP_011509226.1, XM_011510924.1
XP_011509227.1, XM_011510925.1
UniGeneiHs.97316

Genome annotation databases

GeneIDi25791

Similar proteinsi

Entry informationi

Entry nameiB4DDI2_HUMAN
AccessioniPrimary (citable) accession number: B4DDI2
Entry historyiIntegrated into UniProtKB/TrEMBL: September 23, 2008
Last sequence update: September 23, 2008
Last modified: May 23, 2018
This is version 87 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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