UniProtKB - B3W6M6 (B3W6M6_PIG)
Protein
Submitted name:
DNA-binding protein inhibitor ID-1 isoform a
Gene
ID1
Organism
Sus scrofa (Pig)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription factor inhibitor activity Source: Ensembl
- protein dimerization activity Source: InterPro
- protein self-association Source: Ensembl
GO - Biological processi
- BMP signaling pathway Source: Ensembl
- cell differentiation Source: GO_Central
- circadian regulation of gene expression Source: GO_Central
- collagen metabolic process Source: Ensembl
- endothelial cell morphogenesis Source: Ensembl
- heart development Source: Ensembl
- lung morphogenesis Source: Ensembl
- lung vasculature development Source: Ensembl
- negative regulation of apoptotic process Source: Ensembl
- negative regulation of cold-induced thermogenesis Source: Ensembl
- negative regulation of DNA binding Source: Ensembl
- negative regulation of DNA-binding transcription factor activity Source: Ensembl
- negative regulation of osteoblast differentiation Source: Ensembl
- negative regulation of transcription by RNA polymerase II Source: GO_Central
- positive regulation of gene expression Source: Ensembl
- protein destabilization Source: Ensembl
- regulation of angiogenesis Source: Ensembl
- regulation of MAPK cascade Source: Ensembl
- response to antibiotic Source: Ensembl
Enzyme and pathway databases
Reactomei | R-SSC-2559585, Oncogene Induced Senescence |
Names & Taxonomyi
Protein namesi | Submitted name: DNA-binding protein inhibitor ID-1 isoform aImportedSubmitted name: Inhibitor of DNA binding 1, HLH proteinImportedSubmitted name: Inhibitor of DNA binding 1, dominant negative helix-loop-helix proteinImported |
Gene namesi | Name:ID1Imported |
Organismi | Sus scrofa (Pig)Imported |
Taxonomic identifieri | 9823 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Laurasiatheria › Artiodactyla › Suina › Suidae › Sus |
Proteomesi |
|
Organism-specific databases
VGNCi | VGNC:96366, ID1 |
Subcellular locationi
Golgi apparatus
- Golgi apparatus Source: Ensembl
Nucleus
- nucleoplasm Source: Ensembl
- nucleus Source: GO_Central
Expressioni
Gene expression databases
Bgeei | ENSSSCG00000007227, Expressed in forelimb bud and 40 other tissues |
Interactioni
GO - Molecular functioni
- protein dimerization activity Source: InterPro
- protein self-association Source: Ensembl
Protein-protein interaction databases
STRINGi | 9823.ENSSSCP00000007695 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 52 – 104 | BHLHInterPro annotationAdd BLAST | 53 |
Phylogenomic databases
eggNOGi | ENOG502RZP5, Eukaryota |
GeneTreei | ENSGT00940000161109 |
HOGENOMi | CLU_116790_0_0_1 |
OMAi | KSRQHTV |
OrthoDBi | 1624054at2759 |
TreeFami | TF326217 |
Family and domain databases
CDDi | cd00083, HLH, 1 hit |
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR026052, DNA-bd_prot-inh IPR036638, HLH_DNA-bd_sf |
PANTHERi | PTHR11723, PTHR11723, 1 hit |
Pfami | View protein in Pfam PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
i Sequence
Sequence statusi: Complete.
B3W6M6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKVASGSATA TAGPSCALKA GKTAGGAGEV VRCLSEQSVA ISRCAGGPGA
60 70 80 90 100
RLPPLLDEQQ VNVLLYDMNG CYSRLKELVP TLPQNRKVSR VEILQHVIDY
110 120 130 140 150
IWDLELELNS ESQVGTQGGR GLPARAPLST LNGEISALAA ETACVPADDR
ILCR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AEMK02000106 Genomic DNA No translation available. FM173202 Genomic DNA Translation: CAQ64595.1 FM173203 Genomic DNA Translation: CAQ64596.1 DQIR01236686 Transcribed RNA Translation: HDB92163.1 |
RefSeqi | NP_001231629.1, NM_001244700.1 |
Genome annotation databases
Ensembli | ENSSSCT00000064936; ENSSSCP00000040237; ENSSSCG00000037016 |
GeneIDi | 100522839 |
KEGGi | ssc:100522839 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AEMK02000106 Genomic DNA No translation available. FM173202 Genomic DNA Translation: CAQ64595.1 FM173203 Genomic DNA Translation: CAQ64596.1 DQIR01236686 Transcribed RNA Translation: HDB92163.1 |
RefSeqi | NP_001231629.1, NM_001244700.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 9823.ENSSSCP00000007695 |
Genome annotation databases
Ensembli | ENSSSCT00000064936; ENSSSCP00000040237; ENSSSCG00000037016 |
GeneIDi | 100522839 |
KEGGi | ssc:100522839 |
Organism-specific databases
CTDi | 3397 |
VGNCi | VGNC:96366, ID1 |
Phylogenomic databases
eggNOGi | ENOG502RZP5, Eukaryota |
GeneTreei | ENSGT00940000161109 |
HOGENOMi | CLU_116790_0_0_1 |
OMAi | KSRQHTV |
OrthoDBi | 1624054at2759 |
TreeFami | TF326217 |
Enzyme and pathway databases
Reactomei | R-SSC-2559585, Oncogene Induced Senescence |
Gene expression databases
Bgeei | ENSSSCG00000007227, Expressed in forelimb bud and 40 other tissues |
Family and domain databases
CDDi | cd00083, HLH, 1 hit |
Gene3Di | 4.10.280.10, 1 hit |
InterProi | View protein in InterPro IPR011598, bHLH_dom IPR026052, DNA-bd_prot-inh IPR036638, HLH_DNA-bd_sf |
PANTHERi | PTHR11723, PTHR11723, 1 hit |
Pfami | View protein in Pfam PF00010, HLH, 1 hit |
SMARTi | View protein in SMART SM00353, HLH, 1 hit |
SUPFAMi | SSF47459, SSF47459, 1 hit |
PROSITEi | View protein in PROSITE PS50888, BHLH, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B3W6M6_PIG | |
Accessioni | B3W6M6Primary (citable) accession number: B3W6M6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 2, 2008 |
Last sequence update: | September 2, 2008 | |
Last modified: | December 2, 2020 | |
This is version 80 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |