UniProtKB - B3RS94 (B3RS94_TRIAD)
Protein
Tubulin-specific chaperone A
Gene
TRIADDRAFT_54517
Organism
Trichoplax adhaerens (Trichoplax reptans)
Status
Functioni
Tubulin-folding protein; involved in the early step of the tubulin folding pathway.ARBA annotation
GO - Molecular functioni
- beta-tubulin binding Source: InterPro
- tubulin binding Source: GO_Central
GO - Biological processi
- post-chaperonin tubulin folding pathway Source: UniProtKB-UniRule
- protein folding Source: GO_Central
- tubulin complex assembly Source: GO_Central
Keywordsi
Molecular function | ChaperoneUniRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Tubulin-specific chaperone AUniRule annotation |
Gene namesi | ORF Names:TRIADDRAFT_54517Imported |
Organismi | Trichoplax adhaerens (Trichoplax reptans)Imported |
Taxonomic identifieri | 10228 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Placozoa › Trichoplacidae › Trichoplax |
Proteomesi |
|
Subcellular locationi
Cytoskeleton
- cytoskeleton UniRule annotation
Cytoskeleton
- microtubule Source: UniProtKB-KW
- microtubule cytoskeleton Source: GO_Central
Cytosol
- cytosol Source: GO_Central
Keywords - Cellular componenti
Cytoplasm, CytoskeletonUniRule annotation, MicrotubuleUniRule annotationInteractioni
Subunit structurei
Supercomplex made of cofactors A to E. Cofactors A and D function by capturing and stabilizing tubulin in a quasi-native conformation. Cofactor E binds to the cofactor D-tubulin complex; interaction with cofactor C then causes the release of tubulin polypeptides that are committed to the native state.
UniRule annotationGO - Molecular functioni
- beta-tubulin binding Source: InterPro
- tubulin binding Source: GO_Central
Protein-protein interaction databases
STRINGi | 10228.TriadP54517 |
Family & Domainsi
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 18 – 45 | Sequence analysisAdd BLAST | 28 | |
Coiled coili | 70 – 90 | Sequence analysisAdd BLAST | 21 |
Sequence similaritiesi
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
eggNOGi | KOG3470, Eukaryota |
HOGENOMi | CLU_130569_1_1_1 |
InParanoidi | B3RS94 |
OMAi | IMMVPDS |
OrthoDBi | 1471374at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR004226, TBCA IPR036126, TBCA_sf |
PANTHERi | PTHR21500, PTHR21500, 1 hit |
Pfami | View protein in Pfam PF02970, TBCA, 1 hit |
SUPFAMi | SSF46988, SSF46988, 1 hit |
i Sequence
Sequence statusi: Complete.
B3RS94-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MADNAASLRQ LKIKTGVVRR LVKEKAMYEK EVIDQQARID KLKANNEDEY
60 70 80 90 100
VIKKQIEVLQ ESENIIPDCQ KRIKAAIADL QRLLENESNL ASCEEYEVAK
KLLSEVTAQ
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DS985243 Genomic DNA Translation: EDV27015.1 |
RefSeqi | XP_002111011.1, XM_002110975.1 |
Genome annotation databases
EnsemblMetazoai | TriadT54517; TriadP54517; TriadG54517 |
GeneIDi | 6751688 |
KEGGi | tad:TRIADDRAFT_54517 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | DS985243 Genomic DNA Translation: EDV27015.1 |
RefSeqi | XP_002111011.1, XM_002110975.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10228.TriadP54517 |
Genome annotation databases
EnsemblMetazoai | TriadT54517; TriadP54517; TriadG54517 |
GeneIDi | 6751688 |
KEGGi | tad:TRIADDRAFT_54517 |
Organism-specific databases
CTDi | 6751688 |
Phylogenomic databases
eggNOGi | KOG3470, Eukaryota |
HOGENOMi | CLU_130569_1_1_1 |
InParanoidi | B3RS94 |
OMAi | IMMVPDS |
OrthoDBi | 1471374at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR004226, TBCA IPR036126, TBCA_sf |
PANTHERi | PTHR21500, PTHR21500, 1 hit |
Pfami | View protein in Pfam PF02970, TBCA, 1 hit |
SUPFAMi | SSF46988, SSF46988, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B3RS94_TRIAD | |
Accessioni | B3RS94Primary (citable) accession number: B3RS94 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 2, 2008 |
Last sequence update: | September 2, 2008 | |
Last modified: | December 2, 2020 | |
This is version 50 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |