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Protein

Arginine--tRNA ligase

Gene

argS

Organism
Chlorobaculum parvum (strain NCIB 8327) (Chlorobium vibrioforme subsp. thiosulfatophilum (strain DSM 263 / NCIB 8327))
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetase, Ligase
Biological processProtein biosynthesis
LigandATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCPAR517417:G1GC8-2095-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)
Alternative name(s):
Arginyl-tRNA synthetaseUniRule annotation
Short name:
ArgRSUniRule annotation
Gene namesi
Name:argSUniRule annotation
Ordered Locus Names:Cpar_2046
OrganismiChlorobaculum parvum (strain NCIB 8327) (Chlorobium vibrioforme subsp. thiosulfatophilum (strain DSM 263 / NCIB 8327))
Taxonomic identifieri517417 [NCBI]
Taxonomic lineageiBacteriaChlorobiChlorobiaChlorobialesChlorobiaceaeChlorobaculum
Proteomesi
  • UP000008811 Componenti: Chromosome

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_10000953491 – 551Arginine--tRNA ligaseAdd BLAST551

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi517417.Cpar_2046

Structurei

3D structure databases

ProteinModelPortaliB3QLU7
SMRiB3QLU7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Motifi123 – 133"HIGH" regionAdd BLAST11

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit

Sequencei

Sequence statusi: Complete.

B3QLU7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MRAFFLPFIQ DALHKAGIET DKEIQIDKPN DKKFGDFSTN IAFLLAKEAR
60 70 80 90 100
KNPRELATQL IGLFAFPEGT VTKTEVAGPG FINFHLAPAF FMRSAQEVLT
110 120 130 140 150
QGEKFGCTES GKGQKAIVEY VSANPTGPLT IGRGRGGVLG DCIANLLETQ
160 170 180 190 200
GYEVTREYYF NDAGRQMQIL AESVRYRYLE KCGQTVEFPE THYQGDYIGE
210 220 230 240 250
IAGTLFIEHS DELASSDELG IFKETAEAVI FSSIRRTLER IGITHDSFFN
260 270 280 290 300
EHTLYQWNEG EASGNQKVID ALEAKDFIGR YDGATWFMTT KLGQEKDKVL
310 320 330 340 350
IKSSGDPSYR LPDIAYHVTK FERGFDLMVN VFGADHIDEY PDVLEALKIL
360 370 380 390 400
GYDASKVKIA INQFVTTTVG GQTVKMSTRK GNADLLDDLI EDVGADATRL
410 420 430 440 450
FFIMRSKDSH LNFDVELAKK QSKDNPVFYL QYAHARICSL VRLAEKEVGF
460 470 480 490 500
DEAAATGASL PLLDSEPEID LASALLDFPD VIQSCLRLLE PQKMVEYLHT
510 520 530 540 550
VAERYHKFYQ ECPILKADEN IRTARLELSL TVRQVLRNGF RILGISAPES

M
Length:551
Mass (Da):61,729
Last modified:September 2, 2008 - v1
Checksum:iDBB70365D97AEC2A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001099 Genomic DNA Translation: ACF12433.1
RefSeqiWP_012503266.1, NC_011027.1

Genome annotation databases

EnsemblBacteriaiACF12433; ACF12433; Cpar_2046
KEGGicpc:Cpar_2046

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP001099 Genomic DNA Translation: ACF12433.1
RefSeqiWP_012503266.1, NC_011027.1

3D structure databases

ProteinModelPortaliB3QLU7
SMRiB3QLU7
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi517417.Cpar_2046

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiACF12433; ACF12433; Cpar_2046
KEGGicpc:Cpar_2046

Phylogenomic databases

eggNOGiENOG4105C75 Bacteria
COG0018 LUCA
HOGENOMiHOG000247214
KOiK01887
OMAiNKPLHLG
OrthoDBiPOG091H01RF

Enzyme and pathway databases

BioCyciCPAR517417:G1GC8-2095-MONOMER

Family and domain databases

CDDicd00671 ArgRS_core, 1 hit
Gene3Di3.30.1360.70, 1 hit
3.40.50.620, 1 hit
HAMAPiMF_00123 Arg_tRNA_synth, 1 hit
InterProiView protein in InterPro
IPR001278 Arg-tRNA-ligase
IPR005148 Arg-tRNA-synth_N
IPR036695 Arg-tRNA-synth_N_sf
IPR035684 ArgRS_core
IPR008909 DALR_anticod-bd
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PANTHERiPTHR11956 PTHR11956, 1 hit
PfamiView protein in Pfam
PF03485 Arg_tRNA_synt_N, 1 hit
PF05746 DALR_1, 1 hit
PF00750 tRNA-synt_1d, 1 hit
PRINTSiPR01038 TRNASYNTHARG
SMARTiView protein in SMART
SM01016 Arg_tRNA_synt_N, 1 hit
SM00836 DALR_1, 1 hit
SUPFAMiSSF47323 SSF47323, 1 hit
SSF55190 SSF55190, 1 hit
TIGRFAMsiTIGR00456 argS, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiSYR_CHLP8
AccessioniPrimary (citable) accession number: B3QLU7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 24, 2009
Last sequence update: September 2, 2008
Last modified: October 10, 2018
This is version 61 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families
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Main funding by: National Institutes of Health

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