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Protein
Submitted name:

GG12082

Gene

Dere\GG12082

Organism
Drosophila erecta (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function_section">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionMethyltransferaseSAAS annotation, Transferase
LigandMetal-binding, S-adenosyl-L-methionineSAAS annotation, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
GG12082Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Dere\GG12082Imported
ORF Names:Dere_GG12082Imported, GG12082Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila erecta (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7220 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008711 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

Organism-specific databases

Drosophila genome database

More...
FlyBasei
FBgn0104374 Dere\GG12082

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini394 – 467PWWPInterPro annotationAdd BLAST74
Domaini1003 – 1048PHD-typeInterPro annotationAdd BLAST46
Domaini1053 – 1115PWWPInterPro annotationAdd BLAST63
Domaini1186 – 1236AWSInterPro annotationAdd BLAST51
Domaini1238 – 1355SETInterPro annotationAdd BLAST118
Domaini1363 – 1379Post-SETInterPro annotationAdd BLAST17

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotationSAAS annotation

Phylogenomic databases

KEGG Orthology (KO)

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KOi
K11424

Identification of Orthologs from Complete Genome Data

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OMAi
EYVMVHR

Database of Orthologous Groups

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OrthoDBi
EOG091G02U7

Database for complete collections of gene phylogenies

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PhylomeDBi
B3P5V7

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.40.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR006560 AWS_dom
IPR003616 Post-SET_dom
IPR000313 PWWP_dom
IPR001214 SET_dom
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00855 PWWP, 2 hits
PF00856 SET, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

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SMARTi
View protein in SMART
SM00570 AWS, 1 hit
SM00249 PHD, 3 hits
SM00293 PWWP, 2 hits
SM00317 SET, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF57903 SSF57903, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51215 AWS, 1 hit
PS50868 POST_SET, 1 hit
PS50812 PWWP, 2 hits
PS50280 SET, 1 hit
PS01359 ZF_PHD_1, 1 hit
PS50016 ZF_PHD_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B3P5V7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MKLSTDAHSE IEGDGAHGNV LCNSASDSLA GTDEVAAGND ESAVATEGDD
60 70 80 90 100
AEIPQDATNS TPVRRLSKPH PGQSVAEPAG DESELESQRR TPVQKQRLSM
110 120 130 140 150
VNRKRDLINL QSALSPKYIG YANANSPTPL SDSDDTIRTT RRRVNQAAVL
160 170 180 190 200
NTSNSTSETL SRDSASPRTT GGGGGGGGES GGGGSASQLL SKTYMSPIEK
210 220 230 240 250
LLIKNGASSP NSTGFEADSE DLVIRPPVRK QLKRKMKRMP KSKVSLDLEP
260 270 280 290 300
EKVDVEKPVK TEPIDGEVDL AEEAPHYEAE TSTIFIKPET EAENEAAVDV
310 320 330 340 350
LIKQEDTTSL DIVNNPVETT PILVIEEPKE LEKSTEELKF ALPLAASTEV
360 370 380 390 400
DLKSPPDLSS TALGTSIKSP SSVSIDSAKG LSIVTDPGWP TYQVGDLFWG
410 420 430 440 450
KVFSYCFWPC MVCPDPLGQI VGNMPSHPQR LSVDNAIVPI QVHVRFFADN
460 470 480 490 500
GRRNWIKPEN LLTFAGLKAF EDLREEVRIK NGPKSAKYRQ MVPKRTKIVI
510 520 530 540 550
WRQAIEEGHV MTQIPYSDRL EKFYQTYENA VTLNRQKRNR TKSMMQDTSD
560 570 580 590 600
VGSSLYDSTD NLHNKQVTQL LAVKRERSES PFSPAFSPVK SKNEKRVKRR
610 620 630 640 650
KLSNGNEADT GSTSMAVTPS QTETALEKNH TPEGSIYENP EFRQLFDAVK
660 670 680 690 700
EYVMVHRSEE KVEKVLLAVV SNIWSLKQIQ LRELERDLAS GEMEEPLGSS
710 720 730 740 750
VVGRGSGVGT IKRLSNRLKT MMVRRSMTPV VTPSTTPAPS EPDRRLSEAP
760 770 780 790 800
KPKKPVNRPI EEVVEDILQL DSKYLFRGLG REPICKYCYQ AGSDLVRCSR
810 820 830 840 850
SCSSWLHADC LERKETGAPM PKVGSRKALV ISPTSKSPSP DEEHVTADAK
860 870 880 890 900
VVAGGTSLVC HECNVGETEG CVICHQVESP AVPSTPMKEE APSHSPIEDK
910 920 930 940 950
LLTCSQPLCG KRFHTSCCKY WPQANSSKLS ARCPRHVCHT CVSDDPSGKF
960 970 980 990 1000
QQLGSSKLAK CVRCPATYHQ DSHCIPAGTQ MLNATHIICP RHNIAKADAH
1010 1020 1030 1040 1050
VNVLWCYICV KGGELVCCET CPIAVHAHCR NIPIKTNENY ICEECESGRL
1060 1070 1080 1090 1100
PLYGEIVWAK FNNFRWWPAI ILPPTEVPSN ILKKAHGEND FVVRFFGTHD
1110 1120 1130 1140 1150
HGWISRRRVY LYIEGDTGDG HKTKSQLFRN YTTGVEEASR FLKIIKARRQ
1160 1170 1180 1190 1200
EQAIGRQSGV KLHPPPYVKI KTNKAVPPVR FTQNLEDLSA CYCQPGDEHP
1210 1220 1230 1240 1250
CGPDSGCLNR MLFNECNPEF CKAGSRCENQ MFEQRKSPRL EVVYMNERGF
1260 1270 1280 1290 1300
GLVNREPIAE GDFVIEYVGE VINHAEFQRR MEQKQRGRDE NYYFLGVEKD
1310 1320 1330 1340 1350
FIIDAGPKGN LARFMNHSCE PNCETQKWTV NCIHRVGLFA IKDIPANTEL
1360 1370 1380 1390 1400
TFNYLWDDLM NNSKKACFCG ATRCSGEIGG KLKDGAVKET NAQTAKGKAS
1410 1420 1430 1440
AKLKQIRRGK ASVVRIHVKA KKAPKVKHIS ADDEPIDVRN E
Length:1,441
Mass (Da):159,786
Last modified:September 2, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i99A94E4D977E5861
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

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DDBJi
Links Updated
CH954182 Genomic DNA Translation: EDV53357.1

NCBI Reference Sequences

More...
RefSeqi
XP_001981487.1, XM_001981451.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0132136; FBpp0130628; FBgn0104374

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
6554177

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
der:Dere_GG12082

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH954182 Genomic DNA Translation: EDV53357.1
RefSeqiXP_001981487.1, XM_001981451.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0132136; FBpp0130628; FBgn0104374
GeneIDi6554177
KEGGider:Dere_GG12082

Organism-specific databases

FlyBaseiFBgn0104374 Dere\GG12082

Phylogenomic databases

KOiK11424
OMAiEYVMVHR
OrthoDBiEOG091G02U7
PhylomeDBiB3P5V7

Family and domain databases

Gene3Di3.30.40.10, 1 hit
InterProiView protein in InterPro
IPR006560 AWS_dom
IPR003616 Post-SET_dom
IPR000313 PWWP_dom
IPR001214 SET_dom
IPR019786 Zinc_finger_PHD-type_CS
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF00855 PWWP, 2 hits
PF00856 SET, 1 hit
SMARTiView protein in SMART
SM00570 AWS, 1 hit
SM00249 PHD, 3 hits
SM00293 PWWP, 2 hits
SM00317 SET, 1 hit
SUPFAMiSSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS51215 AWS, 1 hit
PS50868 POST_SET, 1 hit
PS50812 PWWP, 2 hits
PS50280 SET, 1 hit
PS01359 ZF_PHD_1, 1 hit
PS50016 ZF_PHD_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB3P5V7_DROER
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B3P5V7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: December 5, 2018
This is version 75 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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