Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Entry version 67 (05 Jun 2019)
Sequence version 1 (02 Sep 2008)
Previous versions | rss
Other tutorials and videosHelp videoFeedback
Protein
Submitted name:

Uncharacterized protein

Gene

Dere\GG14941

Organism
Drosophila erecta (Fruit fly)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Uncharacterized proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Dere\GG14941Imported
ORF Names:Dere_GG14941Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDrosophila erecta (Fruit fly)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7220 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaEcdysozoaArthropodaHexapodaInsectaPterygotaNeopteraHolometabolaDipteraBrachyceraMuscomorphaEphydroideaDrosophilidaeDrosophilaSophophora
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000008711 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Unassembled WGS sequence

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7220.FBpp0133487

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini23 – 96TPR_REGIONInterPro annotationAdd BLAST74
<p>This subsection of the ‘Family and Domains’ section indicates the positions and types of repeated sequence motifs or repeated domains within the protein.<p><a href='/help/repeat' target='_top'>More...</a></p>Repeati23 – 56TPRPROSITE-ProRule annotationAdd BLAST34
Repeati63 – 96TPRPROSITE-ProRule annotationAdd BLAST34
Domaini163 – 196TPR_REGIONInterPro annotationAdd BLAST34
Repeati163 – 196TPRPROSITE-ProRule annotationAdd BLAST34
Repeati245 – 278TPRPROSITE-ProRule annotationAdd BLAST34
Domaini314 – 388TPR_REGIONInterPro annotationAdd BLAST75
Repeati314 – 347TPRPROSITE-ProRule annotationAdd BLAST34
Repeati355 – 388TPRPROSITE-ProRule annotationAdd BLAST34
Domaini538 – 641ANK_REP_REGIONInterPro annotationAdd BLAST104
Repeati538 – 570ANKPROSITE-ProRule annotationAdd BLAST33
Repeati571 – 603ANKPROSITE-ProRule annotationAdd BLAST33
Repeati609 – 641ANKPROSITE-ProRule annotationAdd BLAST33

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni465 – 535DisorderedSequence analysisAdd BLAST71
Regioni694 – 753DisorderedSequence analysisAdd BLAST60
Regioni842 – 880DisorderedSequence analysisAdd BLAST39

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili79 – 99Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi728 – 752PolarSequence analysisAdd BLAST25
Compositional biasi842 – 877PolarSequence analysisAdd BLAST36

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, Coiled coilSequence analysis, TPR repeatPROSITE-ProRule annotation

Phylogenomic databases

KEGG Orthology (KO)

More...
KOi
K09257

Identification of Orthologs from Complete Genome Data

More...
OMAi
ARCYLNI

Database of Orthologous Groups

More...
OrthoDBi
56880at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
B3NF94

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00204 ANK, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.25.40.10, 3 hits
1.25.40.20, 1 hit
3.80.10.10, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR001611 Leu-rich_rpt
IPR032675 LRR_dom_sf
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF12796 Ank_2, 1 hit
PF13516 LRR_6, 2 hits
PF13181 TPR_8, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR01415 ANKYRIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00248 ANK, 3 hits
SM00028 TPR, 6 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48403 SSF48403, 1 hit
SSF48452 SSF48452, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 3 hits
PS50005 TPR, 6 hits
PS50293 TPR_REGION, 3 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B3NF94-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEEKRYLKRK EKARSDGNRD QVAVSCHQLG DFYNQQGKYT DAVREYVQEA
60 70 80 90 100
QIYASMGREL ETAKAKRMVG EMYTLLCDYD AARDHINDYL KIAKRLKNQV
110 120 130 140 150
EEQRAYATLG RVHLLHGQSL ADSSASGSME QLKLAEKNFL RSLLLIKELS
160 170 180 190 200
GQISKLEQLD MQARCYLNIG VVKEHMEDFQ ESIDYIDKAI KISKTHELWD
210 220 230 240 250
LTHLCYISMS LLYNCKKNDA TAALRFCNMA LEVAKRLPNK VKKICETLIT
260 270 280 290 300
KAEILIKAGD FASAKQILTK AYKKNTPDEN DRGNIEKQLR IVVKVCQTLD
310 320 330 340 350
ELVLTSSVDY AKLKSLYEKL GDGCCHLMNY EKALTYYQKM LENAEFNHES
360 370 380 390 400
GKSLVPIYVS LYQTYRDNGQ FDKALEYLWK EFELNQDTPS EAFTTLCTIA
410 420 430 440 450
EICEQQAHPF WTVHDVYQKA LRQADKAGSS TDKLVKIAMV RLRRLMLKHN
460 470 480 490 500
MQVLVENLEA DATAKGIDLD QEESVGDDDE DSDGGGTAVQ QNTPDWDDDF
510 520 530 540 550
DLATLTDSDA SDLDETEKPR PQRTTRGNRT LVIKKNNKGE TQLHQACISG
560 570 580 590 600
NLELVRRLID QGHTVNVRDH AGWLPLHEAC NHGYREIVEL LLDKGAASAI
610 620 630 640 650
NDKGGTSCDG ITPLFDACSN GFLDVAELLL DRGADATVRT DYNETCIAGL
660 670 680 690 700
DKWRQGAQLV DGEQAQYAQL RERLLRTLSK VGICSDKNAR PLTNANAKRI
710 720 730 740 750
SSEERGSLSE EEDEEEALHE SNRRSLSHNR SGSEYAAKKS SSSTQPSASK
760 770 780 790 800
EYRSVMAQLK RPNRLNDDPP STSALIKHKR NAFLREDEVD ADNWLIDDVG
810 820 830 840 850
PERKRKRINS GDLCGRTSKE NFQDTALSLP ANWDEDLLQA TPENEYSQRQ
860 870 880 890 900
KQMRKLTLSR SSSISSNHSS SAAPSRKKHQ VTLLDSGFSR FRSESPLGSE
910 920 930 940 950
SSQDGTTSMF SVRTIEPDST TSTIQVLISP AKSSPIKVQT TPVIATTVSF
960 970 980 990 1000
KVKIQDELLL VPIERKKLQD INIRWLAEEA GRRYNKLTGL TPLLRLKTAD
1010 1020 1030 1040 1050
GFAYEETDAV SVALEQNMLM ATILDWKISP LSQRYEEMCL QVQKTAENKV
1060 1070 1080 1090 1100
KLLLERSQST NMLELSGLWM RAEKTEPIFK ALLHQARLTV LDLSRNFIGN
1110 1120 1130 1140 1150
EGCQQLAKSL PTLLQLKALR LQCNAIGSHG LEALLCGHGM DKLELLEELN
1160 1170 1180 1190 1200
LNQNPLGNGS VRILSRYCAS PAGQALTSLH IAQCELTELQ DFDLGFNKLT
1210 1220 1230 1240 1250
RFDISFNQLT QQSVRRLTDQ LNSCRLEQLN LSYVRWPLDE ASGFALGERL
1260 1270 1280 1290 1300
VALFEGGTCE RFVRVEFAGC GLSDAHMYNV SQHLAKAKQL QWLDISDNRN
1310 1320 1330 1340 1350
LSGTTLGYIL DELPQLRCLL AVNCTNLLDD IRLQKLEQLK QLPRRLELTV
1360 1370 1380 1390 1400
DEQVFSMPGA LETLQSIWQL QFGDKAKMLK TSSSRKSGRR YKGLLKLLAD

GSDAE
Length:1,405
Mass (Da):158,338
Last modified:September 2, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i08BBBE9F435CCC39
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CH954178 Genomic DNA Translation: EDV50436.1

NCBI Reference Sequences

More...
RefSeqi
XP_001971410.1, XM_001971374.2

Genome annotation databases

Ensembl metazoan genome annotation project

More...
EnsemblMetazoai
FBtr0134995; FBpp0133487; FBgn0107195

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
6543838

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
der:6543838

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH954178 Genomic DNA Translation: EDV50436.1
RefSeqiXP_001971410.1, XM_001971374.2

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi7220.FBpp0133487

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblMetazoaiFBtr0134995; FBpp0133487; FBgn0107195
GeneIDi6543838
KEGGider:6543838

Phylogenomic databases

KOiK09257
OMAiARCYLNI
OrthoDBi56880at2759
PhylomeDBiB3NF94

Family and domain databases

CDDicd00204 ANK, 1 hit
Gene3Di1.25.40.10, 3 hits
1.25.40.20, 1 hit
3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR002110 Ankyrin_rpt
IPR020683 Ankyrin_rpt-contain_dom
IPR036770 Ankyrin_rpt-contain_sf
IPR001611 Leu-rich_rpt
IPR032675 LRR_dom_sf
IPR013026 TPR-contain_dom
IPR011990 TPR-like_helical_dom_sf
IPR019734 TPR_repeat
PfamiView protein in Pfam
PF12796 Ank_2, 1 hit
PF13516 LRR_6, 2 hits
PF13181 TPR_8, 1 hit
PRINTSiPR01415 ANKYRIN
SMARTiView protein in SMART
SM00248 ANK, 3 hits
SM00028 TPR, 6 hits
SUPFAMiSSF48403 SSF48403, 1 hit
SSF48452 SSF48452, 2 hits
PROSITEiView protein in PROSITE
PS50297 ANK_REP_REGION, 1 hit
PS50088 ANK_REPEAT, 3 hits
PS50005 TPR, 6 hits
PS50293 TPR_REGION, 3 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB3NF94_DROER
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B3NF94
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: June 5, 2019
This is version 67 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again