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Entry version 69 (10 Apr 2019)
Sequence version 1 (02 Sep 2008)
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Protein
Submitted name:

Phospholipid-transporting ATPase, putative

Gene

PKH_143990

Organism
Plasmodium knowlesi (strain H)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein predictedi <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Phospholipid-transporting ATPase, putativeImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
ORF Names:PKH_143990Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiPlasmodium knowlesi (strain H)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri5851 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaHaemosporidaPlasmodiidaePlasmodiumPlasmodium (Plasmodium)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000031513 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 14

Organism-specific databases

Eukaryotic Pathogen Database Resources

More...
EuPathDBi
PlasmoDB:PKNH_1442600

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular_location_section">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei20 – 37HelicalSequence analysisAdd BLAST18
Transmembranei71 – 100HelicalSequence analysisAdd BLAST30
Transmembranei106 – 128HelicalSequence analysisAdd BLAST23
Transmembranei601 – 619HelicalSequence analysisAdd BLAST19
Transmembranei644 – 663HelicalSequence analysisAdd BLAST20
Transmembranei670 – 690HelicalSequence analysisAdd BLAST21
Transmembranei1445 – 1462HelicalSequence analysisAdd BLAST18
Transmembranei1543 – 1565HelicalSequence analysisAdd BLAST23
Transmembranei1601 – 1622HelicalSequence analysisAdd BLAST22
Transmembranei1634 – 1654HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
B3LCM2

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini54 – 110PhoLip_ATPase_NInterPro annotationAdd BLAST57
Domaini1399 – 1664PhoLip_ATPase_CInterPro annotationAdd BLAST266

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and domains’ section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili289 – 315Sequence analysisAdd BLAST27

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000281069

InParanoid: Eukaryotic Ortholog Groups

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InParanoidi
B3LCM2

KEGG Orthology (KO)

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KOi
K01530

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.40.1110.10, 2 hits
3.40.50.1000, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR023214 HAD_sf
IPR006539 P-type_ATPase_IV
IPR032631 P-type_ATPase_N
IPR001757 P_typ_ATPase
IPR032630 P_typ_ATPase_c

The PANTHER Classification System

More...
PANTHERi
PTHR24092 PTHR24092, 2 hits

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF16212 PhoLip_ATPase_C, 1 hit
PF16209 PhoLip_ATPase_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF56784 SSF56784, 1 hit
SSF81653 SSF81653, 1 hit
SSF81660 SSF81660, 1 hit
SSF81665 SSF81665, 1 hit

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR01494 ATPase_P-type, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B3LCM2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MVDDEELKRL RFVLSKKVGR IKYFFSYMFY KIFSHFYNKK NKKRERFVNI
60 70 80 90 100
HGRTSPQFFC DNKIRSTKYT VITFIPLFLF YQFSDFLNLF YLCVSLLQII
110 120 130 140 150
PIFNTGYVFT FVAPLIFIIL VSLINEVVDD LKRFIKDLEN NNEIYYTLLE
160 170 180 190 200
NGNFEKIYSK DIKVGDIILI KSKQRAPADC ILLRNLSKNE EYTFKVEEKK
210 220 230 240 250
FFGSIKLNKN SNVYNKINKN YYHFNKNIDN ELIDDRYNES NNNLSETSNH
260 270 280 290 300
QLFSENEKSL NGAKEKKFLL KDKPEKSGHK NDMNSSGELA NFEKKKKKKK
310 320 330 340 350
KKKKKKLKNR NLKNKDAGAG GSTETANYTY VKTDKIDGET DWKIKYPISI
360 370 380 390 400
FQNLKKLKDF FTIDILFILE QPKNDIYKIE GSFVIFKYNP HGDFQKEENN
410 420 430 440 450
NTMGMSDNPL MNYSFDMIRD GEVDLERGNR GGVAKAGEPA YGEEDNDDDD
460 470 480 490 500
DDDEDDDDDE EDDEDDDDDG EDDEDERRKE LELENVADGN EKGVHHKGYV
510 520 530 540 550
NLAEKDTDYV YSNNRKEKKM NNEMVKFNDL EKGAVVGVGG SGGTMSGQNR
560 570 580 590 600
GVIENYNCTK NNAKKSGNYV AETSMCSVFN NEDNFNFYNV SYRKKLTYDN
610 620 630 640 650
FILFNSVITS SDVLCLVIYT GSDTRVNMST QISKIKRGMI DNKLNMITLF
660 670 680 690 700
LFLILALFSM YMCTVKLNNL WYLNFIRFVL LFSSVIPISL SVNLNIAKIY
710 720 730 740 750
YTLVIQKDKE IETTIIKNSA IIENFGDVDY IFTDKTGTLT ENVMVLKVIH
760 770 780 790 800
IGLDVIHAEN EKNNMLQGNM ENKGKGNFNK HMLSYDLDDL NEDVDGSSFY
810 820 830 840 850
LGSNYSKNER RNKYSGNKNE LSALRQLNKT VNPMDRINIL HDEENIDEEN
860 870 880 890 900
LDYENFDFGN FNEHSAGSKS GFSQNNYRSA NLKPFKQNSL AMSTSVSGGG
910 920 930 940 950
LGQRRNDIHK KNSVHLEKKK KVEQMVDEFL KYKLDPLDYY NDNVEDVEFL
960 970 980 990 1000
KKHRVFQTFL SFLICNNIRT LAKESNNDGD SNGSVNGTAN GSANDSTNAS
1010 1020 1030 1040 1050
ANGGDSKEKD KVKKKKGEKE TDTQKNFYYI LKVNRKNKKE NKKKKEKHMD
1060 1070 1080 1090 1100
SSSGAFSYDK KNLESNSSED SETFSHSDVS YQCSSPDELA FLKYATNCGF
1110 1120 1130 1140 1150
ILRKKTASRI EIKYKNLVME YDILLHIPFS SETKRMSIFV RNVKNRNIYF
1160 1170 1180 1190 1200
FIKGADNILI KKCHEKYKTF IYEESDHLSN LGLRVLVHGF LNIEEQFFHT
1210 1220 1230 1240 1250
FSNLYNKNKD VKGQLENILD YVEKNIKVLA ITGVEDKLQE GVGKTIEMLY
1260 1270 1280 1290 1300
NSGIKVWVLT GDKIETAICI CKNANIKKKK HNIYIFRHEN IKSTSNLIRD
1310 1320 1330 1340 1350
FNSILSNIDS YVLFFDNIII QNCIKYIPNA FVDFAANARA VVCCRCSPIE
1360 1370 1380 1390 1400
KKEIALLIKT IRRKKILCIG DGGNDVAMIQ AADIGIGVLG KEGKQVVHDS
1410 1420 1430 1440 1450
DIIVSKFKNI KKLILYYGNN TFLQTSSLCS FLIHRGFVLT YLQFIYSYIF
1460 1470 1480 1490 1500
FSIPVSIFQG WLQIGYTTYY TTAPFLSLLL DVKIKKNLIY LYPEIYKNKK
1510 1520 1530 1540 1550
HKRKLDLKSF FIIVWISIFQ VLPDGLRAPT VHAPLLRRQR HTIHYSCELF
1560 1570 1580 1590 1600
FTTSFHLQGT VVMLGALKLF NDNYNNLINI SFSSLIVLEI MNIHLEVESW
1610 1620 1630 1640 1650
HPLMISANIC SFIVYIFSMF ILRNYFDIMQ IMSVMFWYKV ILIVLFAWLP
1660 1670
FFIIKKVKNI LTPSQFFKLA
Length:1,670
Mass (Da):193,299
Last modified:September 2, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i02614AFF3736281D
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AM910996 Genomic DNA Translation: CAQ42181.1

NCBI Reference Sequences

More...
RefSeqi
XP_002262303.1, XM_002262267.1

Genome annotation databases

Ensembl protists genome annotation project

More...
EnsemblProtistsi
CAQ42181; CAQ42181; PKH_143990

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
7323322

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
pkn:PKH_143990

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AM910996 Genomic DNA Translation: CAQ42181.1
RefSeqiXP_002262303.1, XM_002262267.1

3D structure databases

ProteinModelPortaliB3LCM2
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiCAQ42181; CAQ42181; PKH_143990
GeneIDi7323322
KEGGipkn:PKH_143990

Organism-specific databases

EuPathDBiPlasmoDB:PKNH_1442600

Phylogenomic databases

HOGENOMiHOG000281069
InParanoidiB3LCM2
KOiK01530

Family and domain databases

Gene3Di3.40.1110.10, 2 hits
3.40.50.1000, 2 hits
InterProiView protein in InterPro
IPR023299 ATPase_P-typ_cyto_dom_N
IPR018303 ATPase_P-typ_P_site
IPR023298 ATPase_P-typ_TM_dom_sf
IPR008250 ATPase_P-typ_transduc_dom_A_sf
IPR036412 HAD-like_sf
IPR023214 HAD_sf
IPR006539 P-type_ATPase_IV
IPR032631 P-type_ATPase_N
IPR001757 P_typ_ATPase
IPR032630 P_typ_ATPase_c
PANTHERiPTHR24092 PTHR24092, 2 hits
PfamiView protein in Pfam
PF16212 PhoLip_ATPase_C, 1 hit
PF16209 PhoLip_ATPase_N, 1 hit
SUPFAMiSSF56784 SSF56784, 1 hit
SSF81653 SSF81653, 1 hit
SSF81660 SSF81660, 1 hit
SSF81665 SSF81665, 1 hit
TIGRFAMsiTIGR01494 ATPase_P-type, 2 hits
PROSITEiView protein in PROSITE
PS00154 ATPASE_E1_E2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB3LCM2_PLAKH
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B3LCM2
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: April 10, 2019
This is version 69 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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