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Entry version 92 (12 Aug 2020)
Sequence version 1 (02 Sep 2008)
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Protein

DNA helicase

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>This subsection of the <a href="http://www.uniprot.org/help/function%5Fsection">Function</a> section describes the catalytic activity of an enzyme, i.e. a chemical reaction that the enzyme catalyzes.<p><a href='/help/catalytic_activity' target='_top'>More...</a></p>Catalytic activityi

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionChromatin regulatorARBA annotation, DNA-bindingImported, HelicaseImportedARBA annotation, Hydrolase
LigandATP-binding, Metal-binding, Nucleotide-binding, Zinc

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
DNA helicaseARBA annotation (EC:3.6.4.12ARBA annotation)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHomo sapiens (Human)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri9606 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the disease(s) and phenotype(s) associated with a protein.<p><a href='/help/pathology_and_biotech_section' target='_top'>More...</a></p>Pathology & Biotechi

Organism-specific databases

The Pharmacogenetics and Pharmacogenomics Knowledge Base

More...
PharmGKBi
PA26455

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PeptideAtlas

More...
PeptideAtlasi
B3KY63

PRoteomics IDEntifications database

More...
PRIDEi
B3KY63

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
B3KY63, HS

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini344 – 391PHD-typeInterPro annotationAdd BLAST48
Domaini423 – 470PHD-typeInterPro annotationAdd BLAST48
Domaini503 – 560ChromoInterPro annotationAdd BLAST58
Domaini596 – 631ChromoInterPro annotationAdd BLAST36
Domaini712 – 896Helicase ATP-bindingInterPro annotationAdd BLAST185
Domaini1028 – 1177Helicase C-terminalInterPro annotationAdd BLAST150

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 131DisorderedSequence analysisAdd BLAST131
Regioni217 – 334DisorderedSequence analysisAdd BLAST118
Regioni484 – 512DisorderedSequence analysisAdd BLAST29
Regioni552 – 577DisorderedSequence analysisAdd BLAST26
Regioni1318 – 1375DisorderedSequence analysisAdd BLAST58
Regioni1499 – 1536DisorderedSequence analysisAdd BLAST38
Regioni1544 – 1563DisorderedSequence analysisAdd BLAST20
Regioni1568 – 1618DisorderedSequence analysisAdd BLAST51

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili1262 – 1282Sequence analysisAdd BLAST21
Coiled coili1630 – 1651Sequence analysisAdd BLAST22
Coiled coili1821 – 1841Sequence analysisAdd BLAST21

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi33 – 47BasicSequence analysisAdd BLAST15
Compositional biasi62 – 76AcidicSequence analysisAdd BLAST15
Compositional biasi231 – 263PolyampholyteSequence analysisAdd BLAST33
Compositional biasi297 – 311PolarSequence analysisAdd BLAST15
Compositional biasi487 – 508Pro-richSequence analysisAdd BLAST22
Compositional biasi1318 – 1334PolyampholyteSequence analysisAdd BLAST17
Compositional biasi1353 – 1374PolyampholyteSequence analysisAdd BLAST22
Compositional biasi1510 – 1532Pro-richSequence analysisAdd BLAST23
Compositional biasi1544 – 1561PolyampholyteSequence analysisAdd BLAST18
Compositional biasi1580 – 1618PolyampholyteSequence analysisAdd BLAST39

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the SNF2/RAD54 helicase family.ARBA annotation

Keywords - Domaini

Coiled coilSequence analysis, RepeatARBA annotation, Zinc-fingerPROSITE-ProRule annotationARBA annotation

Phylogenomic databases

Database of Orthologous Groups

More...
OrthoDBi
54215at2759

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
3.30.40.10, 2 hits
3.40.50.10810, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR028725, CHD4
IPR012957, CHD_C2
IPR012958, CHD_N
IPR016197, Chromo-like_dom_sf
IPR000953, Chromo/chromo_shadow_dom
IPR023780, Chromo_domain
IPR002464, DNA/RNA_helicase_DEAH_CS
IPR009462, DUF1086
IPR009463, DUF1087
IPR014001, Helicase_ATP-bd
IPR001650, Helicase_C
IPR027417, P-loop_NTPase
IPR038718, SNF2-like_sf
IPR000330, SNF2_N
IPR019786, Zinc_finger_PHD-type_CS
IPR011011, Znf_FYVE_PHD
IPR001965, Znf_PHD
IPR019787, Znf_PHD-finger
IPR013083, Znf_RING/FYVE/PHD

The PANTHER Classification System

More...
PANTHERi
PTHR45623:SF22, PTHR45623:SF22, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08074, CHDCT2, 1 hit
PF08073, CHDNT, 1 hit
PF00385, Chromo, 1 hit
PF06461, DUF1086, 1 hit
PF06465, DUF1087, 1 hit
PF00271, Helicase_C, 1 hit
PF00628, PHD, 2 hits
PF00176, SNF2_N, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00298, CHROMO, 2 hits
SM00487, DEXDc, 1 hit
SM01146, DUF1086, 1 hit
SM01147, DUF1087, 1 hit
SM00490, HELICc, 1 hit
SM00249, PHD, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF52540, SSF52540, 2 hits
SSF54160, SSF54160, 2 hits
SSF57903, SSF57903, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50013, CHROMO_2, 2 hits
PS00690, DEAH_ATP_HELICASE, 1 hit
PS51192, HELICASE_ATP_BIND_1, 1 hit
PS51194, HELICASE_CTER, 1 hit
PS01359, ZF_PHD_1, 2 hits
PS50016, ZF_PHD_2, 2 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B3KY63-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDALLNNSLP PPHPENEEDP EEDLSETETP KLKKKKKPKK PRDPKIPKSK
60 70 80 90 100
RQKKELGDSS GEGPEFVEEE EEVALRSDSE GSDYTPGKKK KKKLGPKKEK
110 120 130 140 150
KSKSKRKEEE EEDDDDDDSK EPKSSAQLLE DWGMEDIDHV FSEEDYRTLT
160 170 180 190 200
NYKAFSQFVR PLIAAKNPKI AVSKMMMVLG AKWREFSTNN PFKGSSGASV
210 220 230 240 250
AAAAAAAVAV VESMVTATEV APPPPPVEVP IRKAKTKEGK GPNARRKPKG
260 270 280 290 300
SPRVPDAKKP KPKKVAPLKI KLGGFGSKRK RSSSEDDDLD VESDFDDASI
310 320 330 340 350
NSYSVSDGST SRSSRSRKKL RTTKKKKKGE EEVTAVDGYE TDHQDYCEVC
360 370 380 390 400
QQGGEIILCD TCPRAYHMVC LDSDMEKAPE GKWSCPHCEK EGIQWEAKED
410 420 430 440 450
NSEGEEILEE VGGDLEEEDD HHMEFCRVCK DGGELLCCDT CPSSYHIHCL
460 470 480 490 500
NPPLPEIPNG EWLCPRCTCP ALKGKVQKIL IWKWGQPPSP TPVPRPPDAD
510 520 530 540 550
PNTPSPKPLE GRPERQFFVK WQGMSYWHCS WVSELQLELH CQVMFRNYQR
560 570 580 590 600
KNDMDEPPSG DFGGDEEKSR KRKNKDPKFA EMEERFYRYG IKPEWMMIHR
610 620 630 640 650
ILNHSVDKKG HVHYLIKWRD LPYDQASWES EDVEIQDYDL FKQSYWNHRE
660 670 680 690 700
LMRGEEGRPG KKLKKVKLRK LERPPETPTV DPTVKYERQP EYLDATGGTL
710 720 730 740 750
HPYQMEGLNW LRFSWAQGTD AILADEMGLG KTVQTAVFLY SLYKEGHSKG
760 770 780 790 800
PFLVSAPLST IINWEREFEM WAPDMYVVTY VGDKDSRAII RENEFSFEDN
810 820 830 840 850
AIRGGKKASR MKKEASVKFH VLLTSYELIT IDMAILGSID WACLIVDEAH
860 870 880 890 900
RLKNNQSKFF RVLNGYSLQH KLLLTGTPLQ NNLEELFHLL NFLTPERFHN
910 920 930 940 950
LEGFLEEFAD IAKEDQIKKL HDMLGPHMLR RLKADVFKNM PSRTELIVRV
960 970 980 990 1000
ELSPMQKKYY KYILTRNFEA LNARGGGNQV SLLNVVMDLK KCCNHPYLFP
1010 1020 1030 1040 1050
VAAMEAPKMP NGMYDGSALI RASGKLLLLQ KMLKNLKEGG HRVLIFSQMT
1060 1070 1080 1090 1100
KMLDLLEDFL EHEGYKYERI DGGITGNMRQ EAIDRFNAPG AQQFCFLLST
1110 1120 1130 1140 1150
RAGGLGINLA TADTVIIYDS DWNPHNDIQA FSRAHRIGQN KKVMIYRFVT
1160 1170 1180 1190 1200
RASVEERITQ VAKKKMMLTH LVVRPGLGSK TGSMSKQELD DILKFGTEEL
1210 1220 1230 1240 1250
FKDEATDGGG DNKEGEDSSV IHYDDKAIER LLDRNQDETE DTELQGMNEY
1260 1270 1280 1290 1300
LSSFKVAQYV VREEEMGEEE EVEREIIKQE ESVDPDYWEK LLRHHYEQQQ
1310 1320 1330 1340 1350
EDLARNLGKG KRIRKQVNYN DGSQEDRDWQ DDQSDNQSDY SVASEEGDED
1360 1370 1380 1390 1400
FDERSEAPRR PSRKGLRNDK DKPLPPLLAR VGGNIEVLGF NARQRKAFLN
1410 1420 1430 1440 1450
AIMRYGMPPQ DAFTTQWLVR DLRGKSEKEF KAYVSLFMRH LCEPGADGAE
1460 1470 1480 1490 1500
TFADGVPREG LSRQHVLTRI GVMSLIRKKV QEFEHVNGRW SMPELAEVEE
1510 1520 1530 1540 1550
NKKMSQPGSP SPKTPTPSTP GDTQPNTPAP VPPAEDGIKI EENSLKEEES
1560 1570 1580 1590 1600
IEGEKEVKST APETAIECTQ APAPASEDEK VVVEPPEGEE KVEKAEVKER
1610 1620 1630 1640 1650
TEEPMETEPK GAADVEKVEE KSAIDLTPIV VEDKEEKKEE EEKKEVMLQN
1660 1670 1680 1690 1700
GETPKDLNDE KQKKNIKQRF MFNIADGGFT ELHSLWQNEE RAATVTKKTY
1710 1720 1730 1740 1750
EIWHRRHDYW LLAGIINHGY ARWQDIQNDP RYAILNEPFK GEMNRGNFLE
1760 1770 1780 1790 1800
IKNKFLARRF KLLEQALVIE EQLRRAAYLN MSEDPSHPSM ALNTRFAEVE
1810 1820 1830 1840 1850
CLAESHQHLS KESMAGNKPA NAVLHKVLKQ LEELLSDMKA DVTRLPATIA
1860 1870 1880
RIPPVAVRLQ MSERNILSRL ANRAPEPTPQ QVAQQQ
Length:1,886
Mass (Da):215,284
Last modified:September 2, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i566F5DA802189A53
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK128741 mRNA Translation: BAG54725.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK128741 mRNA Translation: BAG54725.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Proteomic databases

PeptideAtlasiB3KY63
PRIDEiB3KY63

Protocols and materials databases

The DNASU plasmid repository

More...
DNASUi
1108

Organism-specific databases

PharmGKBiPA26455

Phylogenomic databases

OrthoDBi54215at2759

Gene expression databases

GenevisibleiB3KY63, HS

Family and domain databases

Gene3Di3.30.40.10, 2 hits
3.40.50.10810, 1 hit
InterProiView protein in InterPro
IPR028725, CHD4
IPR012957, CHD_C2
IPR012958, CHD_N
IPR016197, Chromo-like_dom_sf
IPR000953, Chromo/chromo_shadow_dom
IPR023780, Chromo_domain
IPR002464, DNA/RNA_helicase_DEAH_CS
IPR009462, DUF1086
IPR009463, DUF1087
IPR014001, Helicase_ATP-bd
IPR001650, Helicase_C
IPR027417, P-loop_NTPase
IPR038718, SNF2-like_sf
IPR000330, SNF2_N
IPR019786, Zinc_finger_PHD-type_CS
IPR011011, Znf_FYVE_PHD
IPR001965, Znf_PHD
IPR019787, Znf_PHD-finger
IPR013083, Znf_RING/FYVE/PHD
PANTHERiPTHR45623:SF22, PTHR45623:SF22, 1 hit
PfamiView protein in Pfam
PF08074, CHDCT2, 1 hit
PF08073, CHDNT, 1 hit
PF00385, Chromo, 1 hit
PF06461, DUF1086, 1 hit
PF06465, DUF1087, 1 hit
PF00271, Helicase_C, 1 hit
PF00628, PHD, 2 hits
PF00176, SNF2_N, 1 hit
SMARTiView protein in SMART
SM00298, CHROMO, 2 hits
SM00487, DEXDc, 1 hit
SM01146, DUF1086, 1 hit
SM01147, DUF1087, 1 hit
SM00490, HELICc, 1 hit
SM00249, PHD, 2 hits
SUPFAMiSSF52540, SSF52540, 2 hits
SSF54160, SSF54160, 2 hits
SSF57903, SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS50013, CHROMO_2, 2 hits
PS00690, DEAH_ATP_HELICASE, 1 hit
PS51192, HELICASE_ATP_BIND_1, 1 hit
PS51194, HELICASE_CTER, 1 hit
PS01359, ZF_PHD_1, 2 hits
PS50016, ZF_PHD_2, 2 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB3KY63_HUMAN
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B3KY63
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: August 12, 2020
This is version 92 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
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