Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Palmitoyltransferase

Gene

ZDHHC23

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Catalytic activityi

Palmitoyl-CoA + [protein]-L-cysteine = [protein]-S-palmitoyl-L-cysteine + CoA.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionAcyltransferaseUniRule annotation, Transferase

Names & Taxonomyi

Protein namesi
Recommended name:
PalmitoyltransferaseUniRule annotation (EC:2.3.1.225UniRule annotation)
Gene namesi
Name:ZDHHC23Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 3

Organism-specific databases

EuPathDBiHostDB:ENSG00000184307.13
HGNCiHGNC:28654 ZDHHC23

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei82 – 99HelicalUniRule annotationAdd BLAST18
Transmembranei105 – 124HelicalUniRule annotationAdd BLAST20
Transmembranei133 – 150HelicalUniRule annotationAdd BLAST18
Transmembranei162 – 179HelicalUniRule annotationAdd BLAST18
Transmembranei297 – 317HelicalUniRule annotationAdd BLAST21
Transmembranei337 – 364HelicalUniRule annotationAdd BLAST28

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000184307

PTM / Processingi

Proteomic databases

MaxQBiB3KXV3
PRIDEiB3KXV3

Expressioni

Gene expression databases

BgeeiENSG00000184307

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini251 – 379DHHCInterPro annotationAdd BLAST129

Domaini

The DHHC domain is required for palmitoyltransferase activity.UniRule annotation

Sequence similaritiesi

Belongs to the DHHC palmitoyltransferase family.UniRule annotation

Keywords - Domaini

Transmembrane, Transmembrane helixUniRule annotation

Phylogenomic databases

eggNOGiKOG1311 Eukaryota
COG5273 LUCA
GeneTreeiENSGT00880000137864
HOGENOMiHOG000290638
HOVERGENiHBG055654
KOiK18932

Family and domain databases

InterProiView protein in InterPro
IPR001594 Palmitoyltrfase_DHHC
PfamiView protein in Pfam
PF01529 DHHC, 1 hit

Sequencei

Sequence statusi: Complete.

B3KXV3-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKPVKKKKTE EPELEPLCCC EYIDRNGEKN HVATCLCDCQ DLDEGCDRWI
60 70 80 90 100
TCKSLQPETC ERIMDTISDR LRIPWLRGAK KVNISIIPPL VLLPVFLHVA
110 120 130 140 150
SWHFLLGVVV LTSLPVLALW YYYLTHRRKE QTLFFLSLGL FSLGYMYYVF
160 170 180 190 200
LQEVVPKGRV GPVQLAVLTC GLFLILLALH RAKKNPGYLS NPASGDRSLS
210 220 230 240 250
SSQLECLSRK GQEKTKGFPG ADMSGSLNNR TTKDDPKGSS KMPAGSPTKA
260 270 280 290 300
KEDWCAKCQL VRPARAWHCR ICGICVRRMD HHCVWINSCV GESNHQAFIL
310 320 330 340 350
ALLIFLLTSV YGITLTLDTI CRDRSVFTAL FYCPGVYANY SSALSFTCVW
360 370 380 390 400
YSVIITAGMA YIFLIQLINI SYNVTEREVQ QALRQKTGRR LLCGLIVDTG

LLG
Length:403
Mass (Da):45,350
Last modified:September 2, 2008 - v1
Checksum:iD3F35B5ADEAA8DB9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC128687 Genomic DNA No translation available.
AK127996 mRNA Translation: BAG54615.1
RefSeqiNP_775841.2, NM_173570.4
UniGeneiHs.21902

Genome annotation databases

EnsembliENST00000498275; ENSP00000417840; ENSG00000184307
GeneIDi254887
KEGGihsa:254887
UCSCiuc003eav.4 human

Similar proteinsi

Entry informationi

Entry nameiB3KXV3_HUMAN
AccessioniPrimary (citable) accession number: B3KXV3
Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: July 18, 2018
This is version 86 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health