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Protein
Submitted name:

Pescadillo homolog 1, containing BRCT domain (Zebrafish), isoform CRA_b

Gene

PES1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Keywordsi

Biological processRibosome biogenesisSAAS annotation, rRNA processingSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
Pescadillo homolog 1, containing BRCT domain (Zebrafish), isoform CRA_bImported
Submitted name:
cDNA FLJ45250 fis, clone BRHIP2008756, highly similar to Pescadillo homolog 1Imported
Gene namesi
Name:PES1Imported
ORF Names:hCG_2010949Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo
Proteomesi
  • UP000005640 Componenti: Chromosome 22

Organism-specific databases

EuPathDBiHostDB:ENSG00000100029.17
HGNCiHGNC:8848 PES1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

NucleusSAAS annotation

Pathology & Biotechi

Organism-specific databases

OpenTargetsiENSG00000100029

PTM / Processingi

Proteomic databases

MaxQBiB3KXD6
PeptideAtlasiB3KXD6
PRIDEiB3KXD6

Expressioni

Gene expression databases

BgeeiENSG00000100029 Expressed in 204 organ(s), highest expression level in left coronary artery
ExpressionAtlasiB3KXD6 baseline and differential

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini183 – 276BRCTInterPro annotationAdd BLAST94

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili379 – 406Sequence analysisAdd BLAST28

Sequence similaritiesi

Belongs to the pescadillo family.SAAS annotation

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiKOG2481 Eukaryota
COG5163 LUCA
GeneTreeiENSGT00390000002626
HOVERGENiHBG023409

Family and domain databases

CDDicd00027 BRCT, 1 hit
Gene3Di3.40.50.10190, 1 hit
InterProiView protein in InterPro
IPR001357 BRCT_dom
IPR036420 BRCT_dom_sf
IPR010613 PES
PANTHERiPTHR12221 PTHR12221, 1 hit
PfamiView protein in Pfam
PF16589 BRCT_2, 1 hit
PF06732 Pescadillo_N, 1 hit
SMARTiView protein in SMART
SM00292 BRCT, 1 hit
SUPFAMiSSF52113 SSF52113, 1 hit
PROSITEiView protein in PROSITE
PS50172 BRCT, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 4 potential isoforms that are computationally mapped.iShow all

B3KXD6-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MCFLFSTFPR TGKCHVQTIQ LCRRLTVEFM HYIIAARALR KVFLSIKGIY
60 70 80 90 100
YQAEVLGQPI VWITPYAFSH DHPTDVDYRV MATFTEFYTT LLGFVNFRLY
110 120 130 140 150
QLLNLHYPPK LEGQAQAEAK AGEGTYALDS ESCMEKLAAL SASLARVVVP
160 170 180 190 200
ATEEEAEVDE FPTDGEMSAQ EEDRRKELEA QEKHKKLFEG LKFFLNREVP
210 220 230 240 250
REALAFIIRS FGGEVSWDKS LCIGATYDVT DSRITHQIVD RPGQQTSVIG
260 270 280 290 300
RCYVQPQWVF DSVNARLLLP VAEYFSGVQL PPHLSPFVTE KEGDYVPPEK
310 320 330 340 350
LKLLALQRGE DPGNLNESEE EEEEDDNNEG DGDEEGENEE EEEDAEAGSE
360 370 380 390 400
KEEEARLAAL EEQRMEGKKP RVMAGTLKLE DKQRLAQEEE SEAKRLAIMM
410 420 430 440
MKKREKYLYQ KIMFGKRRKI REANKLAEKR KAHDEAVRSE KKAKKARPE
Length:449
Mass (Da):51,464
Last modified:September 2, 2008 - v1
Checksum:i17764B2BF2F0038D
GO

Computationally mapped potential isoform sequencesi

There are 4 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
O00541PESC_HUMAN
Pescadillo homolog
PES1
588Annotation score:
B5MCF9B5MCF9_HUMAN
Pescadillo homolog
PES1
571Annotation score:
H7C267H7C267_HUMAN
Pescadillo homolog
PES1
194Annotation score:
H7BYY8H7BYY8_HUMAN
Pescadillo homolog
PES1
135Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005006 Genomic DNA No translation available.
AK127185 mRNA Translation: BAG54448.1
CH471095 Genomic DNA Translation: EAW59905.1
CH471095 Genomic DNA Translation: EAW59906.1
RefSeqiNP_001269256.1, NM_001282327.1
NP_001269257.1, NM_001282328.1
XP_016884167.1, XM_017028678.1
UniGeneiHs.517543

Genome annotation databases

EnsembliENST00000402281; ENSP00000384366; ENSG00000100029
ENST00000405677; ENSP00000385654; ENSG00000100029
GeneIDi23481
UCSCiuc003ain.2 human

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC005006 Genomic DNA No translation available.
AK127185 mRNA Translation: BAG54448.1
CH471095 Genomic DNA Translation: EAW59905.1
CH471095 Genomic DNA Translation: EAW59906.1
RefSeqiNP_001269256.1, NM_001282327.1
NP_001269257.1, NM_001282328.1
XP_016884167.1, XM_017028678.1
UniGeneiHs.517543

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

MaxQBiB3KXD6
PeptideAtlasiB3KXD6
PRIDEiB3KXD6

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENST00000402281; ENSP00000384366; ENSG00000100029
ENST00000405677; ENSP00000385654; ENSG00000100029
GeneIDi23481
UCSCiuc003ain.2 human

Organism-specific databases

CTDi23481
EuPathDBiHostDB:ENSG00000100029.17
HGNCiHGNC:8848 PES1
OpenTargetsiENSG00000100029
GenAtlasiSearch...

Phylogenomic databases

eggNOGiKOG2481 Eukaryota
COG5163 LUCA
GeneTreeiENSGT00390000002626
HOVERGENiHBG023409

Miscellaneous databases

ChiTaRSiPES1 human
GenomeRNAii23481

Gene expression databases

BgeeiENSG00000100029 Expressed in 204 organ(s), highest expression level in left coronary artery
ExpressionAtlasiB3KXD6 baseline and differential

Family and domain databases

CDDicd00027 BRCT, 1 hit
Gene3Di3.40.50.10190, 1 hit
InterProiView protein in InterPro
IPR001357 BRCT_dom
IPR036420 BRCT_dom_sf
IPR010613 PES
PANTHERiPTHR12221 PTHR12221, 1 hit
PfamiView protein in Pfam
PF16589 BRCT_2, 1 hit
PF06732 Pescadillo_N, 1 hit
SMARTiView protein in SMART
SM00292 BRCT, 1 hit
SUPFAMiSSF52113 SSF52113, 1 hit
PROSITEiView protein in PROSITE
PS50172 BRCT, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB3KXD6_HUMAN
AccessioniPrimary (citable) accession number: B3KXD6
Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: September 12, 2018
This is version 91 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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