UniProtKB - B3KVD5 (B3KVD5_HUMAN)
Protein
Submitted name:
cDNA FLJ16430 fis, clone BRACE3009044, highly similar to Centaurin-gamma 1
Gene
N/A
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- GTPase activator activity Source: UniProtKB-KW
- GTPase activity Source: InterPro
- GTP binding Source: InterPro
- metal ion binding Source: UniProtKB-KW
Keywordsi
Molecular function | GTPase activationARBA annotation |
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: cDNA FLJ16430 fis, clone BRACE3009044, highly similar to Centaurin-gamma 1Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 333 – 566 | PHInterPro annotationAdd BLAST | 234 | |
Domaini | 587 – 707 | Arf-GAPInterPro annotationAdd BLAST | 121 | |
Domaini | 746 – 803 | ANK_REP_REGIONInterPro annotationAdd BLAST | 58 | |
Repeati | 746 – 778 | ANKPROSITE-ProRule annotationAdd BLAST | 33 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 10 – 34 | DisorderedSequence analysisAdd BLAST | 25 | |
Regioni | 239 – 276 | DisorderedSequence analysisAdd BLAST | 38 | |
Regioni | 291 – 329 | DisorderedSequence analysisAdd BLAST | 39 | |
Regioni | 424 – 510 | DisorderedSequence analysisAdd BLAST | 87 | |
Regioni | 809 – 848 | DisorderedSequence analysisAdd BLAST | 40 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 239 – 274 | PolarSequence analysisAdd BLAST | 36 | |
Compositional biasi | 307 – 324 | PolyampholyteSequence analysisAdd BLAST | 18 | |
Compositional biasi | 812 – 833 | PolarSequence analysisAdd BLAST | 22 |
Sequence similaritiesi
Belongs to the centaurin gamma-like family.ARBA annotation
Keywords - Domaini
ANK repeatPROSITE-ProRule annotationARBA annotation, RepeatARBA annotation, Zinc-fingerPROSITE-ProRule annotationARBA annotationFamily and domain databases
Gene3Di | 1.25.40.20, 1 hit 2.30.29.30, 2 hits 3.30.40.160, 1 hit |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR020683, Ankyrin_rpt-contain_dom IPR036770, Ankyrin_rpt-contain_sf IPR037278, ARFGAP/RecO IPR001164, ArfGAP_dom IPR038508, ArfGAP_dom_sf IPR027417, P-loop_NTPase IPR011993, PH-like_dom_sf IPR001849, PH_domain IPR001806, Small_GTPase |
Pfami | View protein in Pfam PF12796, Ank_2, 1 hit PF01412, ArfGap, 1 hit PF00071, Ras, 1 hit |
PRINTSi | PR00405, REVINTRACTNG |
SMARTi | View protein in SMART SM00105, ArfGap, 1 hit SM00233, PH, 1 hit |
SUPFAMi | SSF48403, SSF48403, 1 hit SSF52540, SSF52540, 1 hit SSF57863, SSF57863, 1 hit |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 1 hit PS50088, ANK_REPEAT, 1 hit PS50115, ARFGAP, 1 hit PS50003, PH_DOMAIN, 1 hit |
i Sequence
Sequence statusi: Complete.
B3KVD5-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLKFISGIFT KSTGGPPGSG PLPGPPSLSS GSGSRELLGA ELRASPKAVI
60 70 80 90 100
NSQEWTLSRS IPELRLGVLG DARSGKSSLI HRFLTGSYQV LEKTESEQYK
110 120 130 140 150
KEMLVDGQTH LVLIREEAGA PDAKFSGWAD AVIFVFSLED ENSFQAVSRL
160 170 180 190 200
HGQLSSLRGE GRGGLALALV GTQDRISASS PRVVGDARAR ALCADMKRCS
210 220 230 240 250
YYETCATYGL NVDRVFQEVA QKVVTLRKQQ QLLAACKSLP SSPSHSAAST
260 270 280 290 300
PVAGQASNGG HTSDYSSSLP SSPNVGHREL RAEAAAVAGL STPGSLHRAA
310 320 330 340 350
KRRTSLFANR RGSDSEKRSL DSRGETTGSG RAIPIKQSFL LKRSGNSLNK
360 370 380 390 400
EWKKKYVTLS SNGFLLYHPS INDYIHSTHG KEMDLLRTTV KVPGKRPPRA
410 420 430 440 450
ISAFGPSASI NGLVKDMSTV QMGEGLATTP MPSPSPSPSS LQPPPDQTSK
460 470 480 490 500
HLLKPDRNLA RALSTDCTPS GDLSPLSREP PPSPMVKKQR RKKLTTPSKT
510 520 530 540 550
EGSAGQAEAK RKMWKLKSFG SLRNIYKAEE NFEFLIVSST GQTWHFEAAS
560 570 580 590 600
FEERDAWVQA IESQILASLQ CCESSKVKLR TDSQSEAVAI QAIRNAKGNS
610 620 630 640 650
ICVDCGAPNP TWASLNLGAL ICIECSGIHR NLGTHLSRVR SLDLDDWPRE
660 670 680 690 700
LTLVLTAIGN DTANRVWESD TRGRAKPSRD SSREERESWI RAKYEQLLFL
710 720 730 740 750
APLSTSEEPL GRQLWAAVQA QDVATVLLLL AHARHGPLDT SVEDPQLRSP
760 770 780 790 800
LHLAAELAHV VITQLLLWYG ADVAARDAQG RTALFYARQA GSQLCADILL
810 820 830 840
QHGCPGEGGS AATTPSAATT PSITATPSPR RRSSAASVGR ADAPVALV
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK122827 mRNA Translation: BAG53747.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK122827 mRNA Translation: BAG53747.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | B3KVD5 |
Family and domain databases
Gene3Di | 1.25.40.20, 1 hit 2.30.29.30, 2 hits 3.30.40.160, 1 hit |
InterProi | View protein in InterPro IPR002110, Ankyrin_rpt IPR020683, Ankyrin_rpt-contain_dom IPR036770, Ankyrin_rpt-contain_sf IPR037278, ARFGAP/RecO IPR001164, ArfGAP_dom IPR038508, ArfGAP_dom_sf IPR027417, P-loop_NTPase IPR011993, PH-like_dom_sf IPR001849, PH_domain IPR001806, Small_GTPase |
Pfami | View protein in Pfam PF12796, Ank_2, 1 hit PF01412, ArfGap, 1 hit PF00071, Ras, 1 hit |
PRINTSi | PR00405, REVINTRACTNG |
SMARTi | View protein in SMART SM00105, ArfGap, 1 hit SM00233, PH, 1 hit |
SUPFAMi | SSF48403, SSF48403, 1 hit SSF52540, SSF52540, 1 hit SSF57863, SSF57863, 1 hit |
PROSITEi | View protein in PROSITE PS50297, ANK_REP_REGION, 1 hit PS50088, ANK_REPEAT, 1 hit PS50115, ARFGAP, 1 hit PS50003, PH_DOMAIN, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B3KVD5_HUMAN | |
Accessioni | B3KVD5Primary (citable) accession number: B3KVD5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 2, 2008 |
Last sequence update: | September 2, 2008 | |
Last modified: | October 7, 2020 | |
This is version 85 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |