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UniProtKB - B3KUJ0 (B3KUJ0_HUMAN)
Protein
Submitted name:
cDNA FLJ39996 fis, clone STOMA2002166, highly similar to Splicing factor 3B subunit 4
Gene
N/A
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- RNA binding Source: UniProtKB-UniRule
Keywordsi
Molecular function | RNA-bindingPROSITE-ProRule annotationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: cDNA FLJ39996 fis, clone STOMA2002166, highly similar to Splicing factor 3B subunit 4Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Nucleus
- nucleus Source: UniProtKB-SubCell
Keywords - Cellular componenti
NucleusARBA annotationStructurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 13 – 91 | RRMInterPro annotationAdd BLAST | 79 | |
Domaini | 100 – 179 | RRMInterPro annotationAdd BLAST | 80 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 207 – 424 | DisorderedSequence analysisAdd BLAST | 218 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 232 – 274 | Pro residuesSequence analysisAdd BLAST | 43 | |
Compositional biasi | 327 – 424 | Pro residuesSequence analysisAdd BLAST | 98 |
Sequence similaritiesi
Belongs to the SF3B4 family.ARBA annotation
Keywords - Domaini
RepeatARBA annotationPhylogenomic databases
OrthoDBi | 1479417at2759 |
Family and domain databases
CDDi | cd12334, RRM1_SF3B4, 1 hit cd12335, RRM2_SF3B4, 1 hit |
Gene3Di | 3.30.70.330, 2 hits |
InterProi | View protein in InterPro IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR000504, RRM_dom IPR034158, SF3B4_RRM1 IPR034159, SF3B4_RRM2 |
Pfami | View protein in Pfam PF00076, RRM_1, 2 hits |
SMARTi | View protein in SMART SM00360, RRM, 2 hits |
SUPFAMi | SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50102, RRM, 2 hits |
i Sequence
Sequence statusi: Complete.
B3KUJ0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAAGPISERN QDATVYVGGL DEKVSEPLLW ELFLQAGPVV NTHMPKDRVT
60 70 80 90 100
GQHQGYGFVE FLSEEDADYA IKIMNMIKLY GKPIRVNKAL AHNKNLDVGA
110 120 130 140 150
NIFIENLDPE IDEKLLYDTF SAFGVILQTP KIMRDPDTGN SKGYAFINFA
160 170 180 190 200
SFDASDAAIE AMNGQYLCNR PITVSYAFKK DSKGERHGSA AERLLAAQNP
210 220 230 240 250
LSQADRPHQL FADAPPPPSA PNPVVSSLGS GLPPPGMPPP GSFPPPVPPP
260 270 280 290 300
GALPPGIPPA MPPPPMPPGA AGHGPPSAGT PGAGHPGHGH SHPHPFPPGG
310 320 330 340 350
MPHPGMSQMQ LAHHGPHGLG HPHAGPPGSG GQPPPRPPPG MPHPGPPPMG
360 370 380 390 400
MPPRGPPFGS PMGHPGPMPP HGMRGPPPLM PPHGYTGPPR PPPYGYQRGP
410 420
LPPPRPTPRP PVPPRGPLRG PLPQ
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK097315 mRNA Translation: BAG53452.1 |
RefSeqi | NP_005841.1, NM_005850.4 |
Genome annotation databases
GeneIDi | 10262 |
KEGGi | hsa:10262 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK097315 mRNA Translation: BAG53452.1 |
RefSeqi | NP_005841.1, NM_005850.4 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
IntActi | B3KUJ0, 1 interactor |
Proteomic databases
PeptideAtlasi | B3KUJ0 |
PRIDEi | B3KUJ0 |
Protocols and materials databases
DNASUi | 10262 |
Genome annotation databases
GeneIDi | 10262 |
KEGGi | hsa:10262 |
Organism-specific databases
CTDi | 10262 |
Phylogenomic databases
OrthoDBi | 1479417at2759 |
Miscellaneous databases
BioGRID-ORCSi | 10262, 781 hits in 1081 CRISPR screens |
GenomeRNAii | 10262 |
Gene expression databases
Genevisiblei | B3KUJ0, HS |
Family and domain databases
CDDi | cd12334, RRM1_SF3B4, 1 hit cd12335, RRM2_SF3B4, 1 hit |
Gene3Di | 3.30.70.330, 2 hits |
InterProi | View protein in InterPro IPR012677, Nucleotide-bd_a/b_plait_sf IPR035979, RBD_domain_sf IPR000504, RRM_dom IPR034158, SF3B4_RRM1 IPR034159, SF3B4_RRM2 |
Pfami | View protein in Pfam PF00076, RRM_1, 2 hits |
SMARTi | View protein in SMART SM00360, RRM, 2 hits |
SUPFAMi | SSF54928, SSF54928, 1 hit |
PROSITEi | View protein in PROSITE PS50102, RRM, 2 hits |
MobiDBi | Search... |
Entry informationi
Entry namei | B3KUJ0_HUMAN | |
Accessioni | B3KUJ0Primary (citable) accession number: B3KUJ0 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 2, 2008 |
Last sequence update: | September 2, 2008 | |
Last modified: | May 25, 2022 | |
This is version 63 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |