UniProtKB - B3KRM8 (B3KRM8_HUMAN)
Protein
Component 3 of promoter of RISC
Gene
TSN
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- RNA binding Source: UniProtKB-KW
- sequence-specific DNA binding Source: InterPro
- single-stranded DNA binding Source: InterPro
GO - Biological processi
- RNA metabolic process Source: InterPro
Keywordsi
Molecular function | RNA-bindingARBA annotation |
Names & Taxonomyi
Protein namesi | Recommended name: Component 3 of promoter of RISCARBA annotationAlternative name(s): TranslinARBA annotation |
Gene namesi | Name:TSNImported ORF Names:hCG_37642Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Nucleus
- Nucleus ARBA annotation
Nucleus
- nucleus Source: UniProtKB-SubCell
Keywords - Cellular componenti
NucleusARBA annotationInteractioni
Subunit structurei
Ring-shaped heterooctamer of six TSN and two TSNAX subunits, DNA/RNA binding occurs inside the ring.
ARBA annotationFamily & Domainsi
Sequence similaritiesi
Belongs to the translin family.ARBA annotation
Family and domain databases
CDDi | cd14819, Translin, 1 hit |
Gene3Di | 1.20.58.190, 1 hit 1.20.58.200, 1 hit |
InterProi | View protein in InterPro IPR033956, Translin IPR016069, Translin_C IPR002848, Translin_fam IPR016068, Translin_N IPR036081, Translin_sf |
PANTHERi | PTHR10741, PTHR10741, 1 hit PTHR10741:SF2, PTHR10741:SF2, 1 hit |
Pfami | View protein in Pfam PF01997, Translin, 1 hit |
SUPFAMi | SSF74784, SSF74784, 1 hit |
i Sequence
Sequence statusi: Complete.
B3KRM8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAIMLYVPKR CLKAREHFGT VKTHLTSLKT KFPAEQYYRF HEHWRFVLQR
60 70 80 90 100
LVFLAAFVVY LETETLVTRE AVTEILGIEP DREKGFHLDV EDYLSGVLIL
110 120 130 140 150
ASELSRLSVN SVTAGDYSRP LHISTFINEL DSGFRLLNLK NDSLRKRYDG
160 170 180
LKYDVKKVEE VVYDLSIRGF NKETAAACVE K
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK091915 mRNA Translation: BAG52440.1 CH471103 Genomic DNA Translation: EAW95263.1 |
RefSeqi | NP_001248330.1, NM_001261401.1 |
Genome annotation databases
GeneIDi | 7247 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK091915 mRNA Translation: BAG52440.1 CH471103 Genomic DNA Translation: EAW95263.1 |
RefSeqi | NP_001248330.1, NM_001261401.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | B3KRM8 |
Protocols and materials databases
DNASUi | 7247 |
Genome annotation databases
GeneIDi | 7247 |
Organism-specific databases
CTDi | 7247 |
Miscellaneous databases
BioGRID-ORCSi | 7247, 5 hits in 997 CRISPR screens |
ChiTaRSi | TSN, human |
GenomeRNAii | 7247 |
Family and domain databases
CDDi | cd14819, Translin, 1 hit |
Gene3Di | 1.20.58.190, 1 hit 1.20.58.200, 1 hit |
InterProi | View protein in InterPro IPR033956, Translin IPR016069, Translin_C IPR002848, Translin_fam IPR016068, Translin_N IPR036081, Translin_sf |
PANTHERi | PTHR10741, PTHR10741, 1 hit PTHR10741:SF2, PTHR10741:SF2, 1 hit |
Pfami | View protein in Pfam PF01997, Translin, 1 hit |
SUPFAMi | SSF74784, SSF74784, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B3KRM8_HUMAN | |
Accessioni | B3KRM8Primary (citable) accession number: B3KRM8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 2, 2008 |
Last sequence update: | September 2, 2008 | |
Last modified: | April 7, 2021 | |
This is version 79 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |