UniProtKB - B3KR28 (B3KR28_HUMAN)
Protein
Submitted name:
cDNA FLJ33531 fis, clone BRAMY2007255, highly similar to Toll-interacting protein
Gene
N/A
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- ubiquitin binding Source: InterPro
GO - Biological processi
- autophagy Source: UniProtKB-KW
- inflammatory response Source: UniProtKB-KW
- innate immune response Source: UniProtKB-KW
Keywordsi
Biological process | AutophagyARBA annotation, Immunity, Inflammatory responseARBA annotation, Innate immunityARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: cDNA FLJ33531 fis, clone BRAMY2007255, highly similar to Toll-interacting proteinImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
PTM / Processingi
Proteomic databases
MaxQBi | B3KR28 |
PeptideAtlasi | B3KR28 |
PRIDEi | B3KR28 |
ProteomicsDBi | 3577 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 179 – 222 | CUEInterPro annotationAdd BLAST | 44 |
Sequence similaritiesi
Belongs to the tollip family.ARBA annotation
Family and domain databases
CDDi | cd04016, C2_Tollip, 1 hit cd14363, CUE_TOLIP, 1 hit |
Gene3Di | 2.60.40.150, 1 hit |
InterProi | View protein in InterPro IPR000008, C2_dom IPR035892, C2_domain_sf IPR003892, CUE IPR041799, TOLIP_CUE IPR037301, Tollip_C2 IPR009060, UBA-like_sf |
Pfami | View protein in Pfam PF00168, C2, 1 hit PF02845, CUE, 1 hit |
SMARTi | View protein in SMART SM00546, CUE, 1 hit |
SUPFAMi | SSF46934, SSF46934, 1 hit |
PROSITEi | View protein in PROSITE PS51140, CUE, 1 hit |
i Sequence
Sequence statusi: Complete.
B3KR28-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MATTVSTQRG PAKLAKNYGM TRMDPYCRLR LGYAVYETPT AHNGAKNPRW
60 70 80 90 100
NKVIHCTVPP GVDSFYLEIF DERAFSMDDR IAWTHITIPE SLRQGKVEDK
110 120 130 140 150
WYSLSGRQGD DKEGMINLVM SYALLPAAMV MPPQPVVLMP TVYQQGVGYV
160 170 180 190 200
PITGMPAVCS PGMVPVALPP AAVNAQPRCS EEDLKAIQDM FPNMDQEVIR
210 220
SVLEAQRGNK DAAINSLLQM GEEP
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK090850 mRNA Translation: BAG52240.1 |
RefSeqi | NP_001305441.1, NM_001318512.1 NP_001305443.1, NM_001318514.1 NP_001305444.1, NM_001318515.1 NP_001305445.1, NM_001318516.1 |
Genome annotation databases
GeneIDi | 54472 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK090850 mRNA Translation: BAG52240.1 |
RefSeqi | NP_001305441.1, NM_001318512.1 NP_001305443.1, NM_001318514.1 NP_001305444.1, NM_001318515.1 NP_001305445.1, NM_001318516.1 |
3D structure databases
SMRi | B3KR28 |
ModBasei | Search... |
Proteomic databases
MaxQBi | B3KR28 |
PeptideAtlasi | B3KR28 |
PRIDEi | B3KR28 |
ProteomicsDBi | 3577 |
Genome annotation databases
GeneIDi | 54472 |
Organism-specific databases
CTDi | 54472 |
Miscellaneous databases
BioGRID-ORCSi | 54472, 9 hits in 879 CRISPR screens |
GenomeRNAii | 54472 |
Family and domain databases
CDDi | cd04016, C2_Tollip, 1 hit cd14363, CUE_TOLIP, 1 hit |
Gene3Di | 2.60.40.150, 1 hit |
InterProi | View protein in InterPro IPR000008, C2_dom IPR035892, C2_domain_sf IPR003892, CUE IPR041799, TOLIP_CUE IPR037301, Tollip_C2 IPR009060, UBA-like_sf |
Pfami | View protein in Pfam PF00168, C2, 1 hit PF02845, CUE, 1 hit |
SMARTi | View protein in SMART SM00546, CUE, 1 hit |
SUPFAMi | SSF46934, SSF46934, 1 hit |
PROSITEi | View protein in PROSITE PS51140, CUE, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B3KR28_HUMAN | |
Accessioni | B3KR28Primary (citable) accession number: B3KR28 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 2, 2008 |
Last sequence update: | September 2, 2008 | |
Last modified: | February 10, 2021 | |
This is version 82 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |