UniProtKB - B3KPN2 (B3KPN2_HUMAN)
Protein
Submitted name:
cDNA FLJ31987 fis, clone NT2RP7008855, highly similar to Connector enhancer of kinase suppressor of ras 2
Gene
N/A
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- kinase activity Source: UniProtKB-KW
GO - Biological processi
- regulation of signal transduction Source: InterPro
Keywordsi
Molecular function | KinaseImported, Transferase |
Names & Taxonomyi
Protein namesi | Submitted name: cDNA FLJ31987 fis, clone NT2RP7008855, highly similar to Connector enhancer of kinase suppressor of ras 2Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 162 – 261 | PHInterPro annotationAdd BLAST | 100 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 73 – 102 | DisorderedSequence analysisAdd BLAST | 30 | |
Regioni | 131 – 151 | DisorderedSequence analysisAdd BLAST | 21 | |
Regioni | 274 – 358 | DisorderedSequence analysisAdd BLAST | 85 | |
Regioni | 454 – 490 | DisorderedSequence analysisAdd BLAST | 37 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 135 – 151 | BasicSequence analysisAdd BLAST | 17 | |
Compositional biasi | 274 – 288 | PolyampholyteSequence analysisAdd BLAST | 15 | |
Compositional biasi | 290 – 304 | Pro-richSequence analysisAdd BLAST | 15 | |
Compositional biasi | 318 – 358 | PolarSequence analysisAdd BLAST | 41 | |
Compositional biasi | 463 – 482 | AcidicSequence analysisAdd BLAST | 20 |
Family and domain databases
Gene3Di | 2.30.29.30, 1 hit |
InterProi | View protein in InterPro IPR010599, CNKSR2 IPR011993, PH-like_dom_sf IPR001849, PH_domain |
Pfami | View protein in Pfam PF06663, DUF1170, 2 hits PF00169, PH, 1 hit |
SMARTi | View protein in SMART SM00233, PH, 1 hit |
PROSITEi | View protein in PROSITE PS50003, PH_DOMAIN, 1 hit |
i Sequence
Sequence statusi: Complete.
B3KPN2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MVGKPVHKGS ESPNSFLDQE YRKRFNIVEE DTVLYCYEYE KGRSSSQGRR
60 70 80 90 100
ESTPTYENSL LRYMSNEKIA QEEYMFQRNS KKDTGKKSKK KGDKSNSPTH
110 120 130 140 150
YSLLPSLQMD ALRQDIMGTP VPETTLYHTF QQSSLQHKSK KKNKGPIAGK
160 170 180 190 200
SKRRISCKDL GRGDCEGWLW KKKDAKSYFS QKWKKYWFVL KDASLYWYIN
210 220 230 240 250
EEDEKAEGFI SLPEFKIDRA SECRKKYAFK ACHPKIKSFY FAAEHLDDMN
260 270 280 290 300
RWLNRINMLT AGYAERERIK QEQDYWSESD KEEADTPSTP KQDSPPPPYD
310 320 330 340 350
TYPRPPSMSC ASPYVEAKHS RLSSTETSQS QSSHEEFRQE VTGSSAVSPI
360 370 380 390 400
RKTASQRRSW QDLIETPLTS SGLHYLQTLP LEDSVFSDSA AISPEHRRQS
410 420 430 440 450
TLPTQKCHLQ DHYGPYPLAE SERMQVLNGN GGKPRSFTLP RDSGFNHCCL
460 470 480 490
NAPVSACDPQ DDVQPPEVEE EEEEEEEEGE AAGENIGEKS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK056549 mRNA Translation: BAG51744.1 |
RefSeqi | NP_001162119.1, NM_001168648.2 NP_001162120.1, NM_001168649.2 |
Genome annotation databases
GeneIDi | 22866 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK056549 mRNA Translation: BAG51744.1 |
RefSeqi | NP_001162119.1, NM_001168648.2 NP_001162120.1, NM_001168649.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | B3KPN2 |
Protocols and materials databases
DNASUi | 22866 |
Genome annotation databases
GeneIDi | 22866 |
Organism-specific databases
CTDi | 22866 |
PharmGKBi | PA134867759 |
Miscellaneous databases
BioGRID-ORCSi | 22866, 5 hits in 613 CRISPR screens |
GenomeRNAii | 22866 |
Gene expression databases
Genevisiblei | B3KPN2, HS |
Family and domain databases
Gene3Di | 2.30.29.30, 1 hit |
InterProi | View protein in InterPro IPR010599, CNKSR2 IPR011993, PH-like_dom_sf IPR001849, PH_domain |
Pfami | View protein in Pfam PF06663, DUF1170, 2 hits PF00169, PH, 1 hit |
SMARTi | View protein in SMART SM00233, PH, 1 hit |
PROSITEi | View protein in PROSITE PS50003, PH_DOMAIN, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B3KPN2_HUMAN | |
Accessioni | B3KPN2Primary (citable) accession number: B3KPN2 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 2, 2008 |
Last sequence update: | September 2, 2008 | |
Last modified: | April 7, 2021 | |
This is version 74 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |