UniProtKB - B3KNX9 (B3KNX9_HUMAN)
Protein
Alpha/beta hydrolase domain-containing protein 16A
Gene
BAT5
Organism
Homo sapiens (Human)
Status
Functioni
Catalytic activityi
- Hydrolyzes glycerol monoesters of long-chain fatty acids.ARBA annotation EC:3.1.1.23
GO - Molecular functioni
- acylglycerol lipase activity Source: UniProtKB-EC
Keywordsi
Molecular function | HydrolaseARBA annotation |
Protein family/group databases
ESTHERi | human-ABHD16A, ABHD16 |
Names & Taxonomyi
Protein namesi | Recommended name: Alpha/beta hydrolase domain-containing protein 16AARBA annotation (EC:3.1.1.23ARBA annotation)Alternative name(s): Monoacylglycerol lipase ABHD16AARBA annotation Phosphatidylserine lipase ABHD16AARBA annotation |
Gene namesi | Name:BAT5Imported ORF Names:hCG_43724Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Other locations
- integral component of membrane Source: UniProtKB-KW
Keywords - Cellular componenti
MembraneFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 62 – 188 | AB hydrolase-1InterPro annotationAdd BLAST | 127 |
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixARBA annotationFamily and domain databases
Gene3Di | 3.40.50.1820, 1 hit |
InterProi | View protein in InterPro IPR029058, AB_hydrolase IPR000073, AB_hydrolase_1 IPR026604, ABHD16A |
PANTHERi | PTHR12277:SF54, PTHR12277:SF54, 1 hit |
Pfami | View protein in Pfam PF00561, Abhydrolase_1, 1 hit |
SUPFAMi | SSF53474, SSF53474, 1 hit |
i Sequence
Sequence statusi: Complete.
B3KNX9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLYPGSVYLL QKALMPVLLQ GQARLVEECN GRRAKLLACD GNEIDTMFVD
60 70 80 90 100
RRGTAEPQGQ KLVICCEGNA GFYEVGCVST PLEAGYSVLG WNHPGFAGST
110 120 130 140 150
GVPFPQNEAN AMDVVVQFAI HRLGFQPQDI IIYAWSIGGF TATWAAMSYP
160 170 180 190 200
DVSAMILDAS FDDLVPLALK VMPDSWRGLV TRTVRQHLNL NNAEQLCRYQ
210 220 230 240 250
GPVLLIRRTK DEIITTTVPE DIMSNRGNDL LLKLLQHRYP RVMAEEGLRV
260 270 280 290 300
VRQWLEASSQ LEEASIYSRW EVEEDWCLSV LRSYQAEHGP DFPWSVGEDM
310 320 330
SADGRRQLAL FLARKHLHNF EATHCTPLPA QNFQMPWHL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK055255 mRNA Translation: BAG51491.1 AK297235 mRNA Translation: BAH12526.1 CH471081 Genomic DNA Translation: EAX03482.1 CH471081 Genomic DNA Translation: EAX03484.1 |
RefSeqi | NP_001170986.1, NM_001177515.1 |
Genome annotation databases
GeneIDi | 7920 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK055255 mRNA Translation: BAG51491.1 AK297235 mRNA Translation: BAH12526.1 CH471081 Genomic DNA Translation: EAX03482.1 CH471081 Genomic DNA Translation: EAX03484.1 |
RefSeqi | NP_001170986.1, NM_001177515.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein family/group databases
ESTHERi | human-ABHD16A, ABHD16 |
Proteomic databases
MaxQBi | B3KNX9 |
PeptideAtlasi | B3KNX9 |
PRIDEi | B3KNX9 |
Protocols and materials databases
DNASUi | 7920 |
Genome annotation databases
GeneIDi | 7920 |
Organism-specific databases
CTDi | 7920 |
PharmGKBi | PA25266 |
Miscellaneous databases
BioGRID-ORCSi | 7920, 13 hits in 983 CRISPR screens |
ChiTaRSi | ABHD16A, human |
GenomeRNAii | 7920 |
Family and domain databases
Gene3Di | 3.40.50.1820, 1 hit |
InterProi | View protein in InterPro IPR029058, AB_hydrolase IPR000073, AB_hydrolase_1 IPR026604, ABHD16A |
PANTHERi | PTHR12277:SF54, PTHR12277:SF54, 1 hit |
Pfami | View protein in Pfam PF00561, Abhydrolase_1, 1 hit |
SUPFAMi | SSF53474, SSF53474, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B3KNX9_HUMAN | |
Accessioni | B3KNX9Primary (citable) accession number: B3KNX9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 2, 2008 |
Last sequence update: | September 2, 2008 | |
Last modified: | April 7, 2021 | |
This is version 91 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |