UniProtKB - B3KNS9 (B3KNS9_HUMAN)
Protein
Submitted name:
cDNA FLJ30326 fis, clone BRACE2007174, highly similar to Zinc finger protein 250
Gene
N/A
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- metal ion binding Source: UniProtKB-KW
GO - Biological processi
- regulation of transcription, DNA-templated Source: InterPro
Keywordsi
Ligand | Metal-binding, Zinc |
Names & Taxonomyi
Protein namesi | Submitted name: cDNA FLJ30326 fis, clone BRACE2007174, highly similar to Zinc finger protein 250Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 22 – 93 | KRABInterPro annotationAdd BLAST | 72 | |
Domaini | 199 – 226 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 227 – 254 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 255 – 282 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 283 – 310 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 311 – 338 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 339 – 366 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 367 – 394 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 395 – 422 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 423 – 450 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 451 – 478 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 479 – 506 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 507 – 534 | C2H2-typeInterPro annotationAdd BLAST | 28 | |
Domaini | 535 – 560 | C2H2-typeInterPro annotationAdd BLAST | 26 |
Keywords - Domaini
RepeatARBA annotation, Zinc-fingerPROSITE-ProRule annotationARBA annotationPhylogenomic databases
OMAi | CMQQDSL |
Family and domain databases
CDDi | cd07765, KRAB_A-box, 1 hit |
InterProi | View protein in InterPro IPR001909, KRAB IPR036051, KRAB_dom_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF01352, KRAB, 1 hit PF00096, zf-C2H2, 13 hits |
SMARTi | View protein in SMART SM00349, KRAB, 1 hit SM00355, ZnF_C2H2, 13 hits |
SUPFAMi | SSF109640, SSF109640, 1 hit SSF57667, SSF57667, 7 hits |
PROSITEi | View protein in PROSITE PS50805, KRAB, 1 hit PS00028, ZINC_FINGER_C2H2_1, 13 hits PS50157, ZINC_FINGER_C2H2_2, 13 hits |
i Sequence
Sequence statusi: Complete.
B3KNS9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAAARLLPVP AGPQPLSFQA KLTFEDVAVL LSQDEWDRLC PAQRGLYRNV
60 70 80 90 100
MMETYGNVVS LGLPGSKPDI ISQLERGEDP WVLDRKGAKK SQGLWSDYSD
110 120 130 140 150
NLKYDHTTAC TQQDSLSCPW ECETKGESQN TDLSPKPLIS EQTVILGKTP
160 170 180 190 200
LGRIDQENNE TKQSFCLSPN SVDHREVQVL SQSMPLTPHQ AVPSGERPYM
210 220 230 240 250
CVECGKCFGR SSHLLQHQRI HTGEKPYVCS VCGKAFSQSS VLSKHRRIHT
260 270 280 290 300
GEKPYECNEC GKAFRVSSDL AQHHKIHTGE KPHECLECRK AFTQLSHLIQ
310 320 330 340 350
HQRIHTGERP YVCPLCGKAF NHSTALRSHQ RVHTGEKPHR CNECGKTFSV
360 370 380 390 400
KRTLLQHQRI HTGEKPYTCS ECGKAFSDRS VLIQHHNVHT GEKPYECSEC
410 420 430 440 450
GKTFSHRSTL MNHERIHTEE KPYACYECGK AFVQHSHLIQ HQRVHTGEKP
460 470 480 490 500
YVCGECGHAF SARRSLIQHE RIHTGEKPFQ CTECGKAFSL KATLIVHLRT
510 520 530 540 550
HTGEKPYECN SCGKAFSQYS VLIQHQRIHT GEKPYECGEC GRAFNQHGHL
560
IQHQKVHRKL
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK054888 mRNA Translation: BAG51441.1 |
RefSeqi | NP_001103159.1, NM_001109689.3 NP_066405.1, NM_021061.4 |
Genome annotation databases
GeneIDi | 58500 |
KEGGi | hsa:58500 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK054888 mRNA Translation: BAG51441.1 |
RefSeqi | NP_001103159.1, NM_001109689.3 NP_066405.1, NM_021061.4 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | B3KNS9 |
Protocols and materials databases
DNASUi | 58500 |
Genome annotation databases
GeneIDi | 58500 |
KEGGi | hsa:58500 |
Organism-specific databases
CTDi | 58500 |
PharmGKBi | PA37622 |
Phylogenomic databases
OMAi | CMQQDSL |
Miscellaneous databases
BioGRID-ORCSi | 58500, 6 hits in 1018 CRISPR screens |
GenomeRNAii | 58500 |
Gene expression databases
Genevisiblei | B3KNS9, HS |
Family and domain databases
CDDi | cd07765, KRAB_A-box, 1 hit |
InterProi | View protein in InterPro IPR001909, KRAB IPR036051, KRAB_dom_sf IPR036236, Znf_C2H2_sf IPR013087, Znf_C2H2_type |
Pfami | View protein in Pfam PF01352, KRAB, 1 hit PF00096, zf-C2H2, 13 hits |
SMARTi | View protein in SMART SM00349, KRAB, 1 hit SM00355, ZnF_C2H2, 13 hits |
SUPFAMi | SSF109640, SSF109640, 1 hit SSF57667, SSF57667, 7 hits |
PROSITEi | View protein in PROSITE PS50805, KRAB, 1 hit PS00028, ZINC_FINGER_C2H2_1, 13 hits PS50157, ZINC_FINGER_C2H2_2, 13 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B3KNS9_HUMAN | |
Accessioni | B3KNS9Primary (citable) accession number: B3KNS9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 2, 2008 |
Last sequence update: | September 2, 2008 | |
Last modified: | April 7, 2021 | |
This is version 83 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |