UniProtKB - B3KNK9 (B3KNK9_HUMAN)
Protein
Submitted name:
Epididymis luminal protein 46
Gene
HEL46
Organism
Homo sapiens (Human)
Status
Functioni
GO - Biological processi
- nucleus organization Source: Ensembl
- regulation of lipid metabolic process Source: Ensembl
Names & Taxonomyi
Protein namesi | Submitted name: Epididymis luminal protein 46ImportedSubmitted name: Golgi phosphoprotein 2, isoform CRA_aImportedSubmitted name: cDNA FLJ14811 fis, clone NT2RP4001975, highly similar to Golgi phosphoprotein 2ImportedSubmitted name: cDNA PSEC0257 fis, clone NT2RP3003642, highly similar to golgi phosphoprotein 2Imported |
Gene namesi | Name:HEL46Imported Synonyms:GOLPH2Imported ORF Names:hCG_29469Imported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Organism-specific databases
VEuPathDBi | HostDB:ENSG00000135052.16 |
Subcellular locationi
Other locations
- Membrane ARBA annotation; Single-pass type II membrane protein ARBA annotation
Golgi apparatus
- Golgi apparatus Source: HPA
Other locations
- integral component of membrane Source: UniProtKB-KW
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSG00000135052, Expressed in prostate gland and 221 other tissues |
ExpressionAtlasi | B3KNK9, baseline and differential |
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 178 – 401 | DisorderedSequence analysisAdd BLAST | 224 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 39 – 59 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 67 – 87 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 110 – 144 | Sequence analysisAdd BLAST | 35 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 187 – 206 | PolarSequence analysisAdd BLAST | 20 | |
Compositional biasi | 224 – 242 | PolarSequence analysisAdd BLAST | 19 | |
Compositional biasi | 245 – 283 | PolyampholyteSequence analysisAdd BLAST | 39 | |
Compositional biasi | 314 – 351 | PolyampholyteSequence analysisAdd BLAST | 38 | |
Compositional biasi | 377 – 401 | PolyampholyteSequence analysisAdd BLAST | 25 |
Sequence similaritiesi
Belongs to the GOLM family.ARBA annotation
Keywords - Domaini
Coiled coilSequence analysisARBA annotation, Transmembrane, Transmembrane helixARBA annotationPhylogenomic databases
HOGENOMi | CLU_055640_0_0_1 |
OMAi | QREKRNH |
OrthoDBi | 1073183at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR026143, GOLM1 IPR026139, GOLM1/CASC4 |
PANTHERi | PTHR15896, PTHR15896, 1 hit PTHR15896:SF8, PTHR15896:SF8, 1 hit |
PRINTSi | PR02084, GOLM1CASC4 |
i Sequence
Sequence statusi: Complete.
B3KNK9-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MMGLGNGRRS MKSPPLVLAA LVACIIVLGF NYWIASSRSV DLQTRIMELE
60 70 80 90 100
GRVRRAAAER GAVELKKNEF QGELEKQREQ LDKIQSSHNF QLESVNKLYQ
110 120 130 140 150
DEKAVLVNNI TTGERLIRVL QDQLKTLQRN YGRLQQDVLQ FQKNQTNLER
160 170 180 190 200
KFSYDLSQCI NQMKEVKEQC EERIEEVTKK GNEAVASRDL SENNDQRQQL
210 220 230 240 250
QALSEPQPRL QAAGLPHTEV PQGKGNVLGN SKSQTPAPSS EVVLDSKRQV
260 270 280 290 300
EKEETNEIQV VNEEPQRDRL PQEPGREQVV EDRPVGGRGF GGAGELGQTP
310 320 330 340 350
QVQAALSVSQ ENPEMEGPER DQLVIPDGQE EEQEAAGEGR NQQKLRGEDD
360 370 380 390 400
YNMDENEAES ETDKQAALAG NDRNIDVFNV EDQKRDTINL LDQREKRNHT
L
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | EU794616 mRNA Translation: ACJ13670.1 AK027717 mRNA Translation: BAG51371.1 AK075557 mRNA Translation: BAG52167.1 CH471089 Genomic DNA Translation: EAW62705.1 CH471089 Genomic DNA Translation: EAW62706.1 |
RefSeqi | NP_057632.2, NM_016548.3 NP_808800.1, NM_177937.2 |
Genome annotation databases
GeneIDi | 51280 |
KEGGi | hsa:51280 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | EU794616 mRNA Translation: ACJ13670.1 AK027717 mRNA Translation: BAG51371.1 AK075557 mRNA Translation: BAG52167.1 CH471089 Genomic DNA Translation: EAW62705.1 CH471089 Genomic DNA Translation: EAW62706.1 |
RefSeqi | NP_057632.2, NM_016548.3 NP_808800.1, NM_177937.2 |
3D structure databases
SMRi | B3KNK9 |
ModBasei | Search... |
Protein-protein interaction databases
IntActi | B3KNK9, 2 interactors |
Proteomic databases
PRIDEi | B3KNK9 |
Protocols and materials databases
Antibodypediai | 2449, 694 antibodies |
DNASUi | 51280 |
Genome annotation databases
GeneIDi | 51280 |
KEGGi | hsa:51280 |
Organism-specific databases
CTDi | 51280 |
PharmGKBi | PA28811 |
VEuPathDBi | HostDB:ENSG00000135052.16 |
Phylogenomic databases
HOGENOMi | CLU_055640_0_0_1 |
OMAi | QREKRNH |
OrthoDBi | 1073183at2759 |
Miscellaneous databases
BioGRID-ORCSi | 51280, 4 hits in 872 CRISPR screens |
ChiTaRSi | GOLM1, human |
GenomeRNAii | 51280 |
Gene expression databases
Bgeei | ENSG00000135052, Expressed in prostate gland and 221 other tissues |
ExpressionAtlasi | B3KNK9, baseline and differential |
Family and domain databases
InterProi | View protein in InterPro IPR026143, GOLM1 IPR026139, GOLM1/CASC4 |
PANTHERi | PTHR15896, PTHR15896, 1 hit PTHR15896:SF8, PTHR15896:SF8, 1 hit |
PRINTSi | PR02084, GOLM1CASC4 |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B3KNK9_HUMAN | |
Accessioni | B3KNK9Primary (citable) accession number: B3KNK9 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | September 2, 2008 |
Last sequence update: | September 2, 2008 | |
Last modified: | February 10, 2021 | |
This is version 106 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |