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Protein
Submitted name:

cDNA FLJ14679 fis, clone NT2RP2004232, highly similar to Serine/threonine-protein kinase D3

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.SAAS annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseSAAS annotation, Transferase
LigandATP-bindingSAAS annotation, Metal-binding, Nucleotide-binding, Zinc

Enzyme and pathway databases

SignaLinkiB3KNJ2

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ14679 fis, clone NT2RP2004232, highly similar to Serine/threonine-protein kinase D3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

PTM / Processingi

Proteomic databases

PeptideAtlasiB3KNJ2
PRIDEiB3KNJ2

Structurei

3D structure databases

ProteinModelPortaliB3KNJ2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini12 – 62Phorbol-ester/DAG-typeInterPro annotationAdd BLAST51
Domaini157 – 273PHInterPro annotationAdd BLAST117
Domaini317 – 573Protein kinaseInterPro annotationAdd BLAST257

Keywords - Domaini

Zinc-fingerSAAS annotation

Phylogenomic databases

eggNOGiKOG4236 Eukaryota
ENOG410XQZ3 LUCA
HOVERGENiHBG003564

Family and domain databases

CDDicd00029 C1, 1 hit
Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR020454 DAG/PE-bd
IPR011009 Kinase-like_dom_sf
IPR002219 PE/DAG-bd
IPR011993 PH-like_dom_sf
IPR001849 PH_domain
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR015727 Protein_Kinase_C_mu-related
IPR008271 Ser/Thr_kinase_AS
PANTHERiPTHR22968 PTHR22968, 1 hit
PfamiView protein in Pfam
PF00130 C1_1, 1 hit
PF00169 PH, 1 hit
PF00069 Pkinase, 1 hit
PRINTSiPR00008 DAGPEDOMAIN
SMARTiView protein in SMART
SM00109 C1, 1 hit
SM00233 PH, 1 hit
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50003 PH_DOMAIN, 1 hit
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit
PS00479 ZF_DAG_PE_1, 1 hit
PS50081 ZF_DAG_PE_2, 1 hit

Sequencei

Sequence statusi: Complete.

B3KNJ2-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MEKMVMCRVK VPHTFAVHSY TRPTICQYCK RLLKGLFRQG MQCKDCKFNC
60 70 80 90 100
HKRCASKVPR DCLGEVTFNG EPSSLGTDTD IPMDIDNNDI NSDSSRGLDD
110 120 130 140 150
TEEPSPPEDK MFFLDPSDLD VERDEEAVKT ISPSTSNNIP LMRVVQSIKH
160 170 180 190 200
TKRKSSTMVK EGWMVHYTSR DNLRKRHYWR LDSKCLTLFQ NESGSKYYKE
210 220 230 240 250
IPLSEILRIS SPRDFTNISQ GSNPHCFEII TDTMVYFVGE NNGDSSHNPV
260 270 280 290 300
LAATGVGLDV AQSWEKAIRQ ALMPVTPQAS VCTSPGQGKD HKDLSTSISV
310 320 330 340 350
SNCQIQENVD ISTVYQIFAD EVLGSGQFGI VYGGKHRKTG RDVAIKVIDK
360 370 380 390 400
MRFPTKQESQ LRNEVAILQN LHHPGIVNLE CMFETPERVF VVMEKLHGDM
410 420 430 440 450
LEMILSSEKS RLPERITKFM VTQILVALRN LHFKNIVHCD LKPENVLLAS
460 470 480 490 500
AEPFPQVKLC DFGFARIIGE KSFRRSVVGT PAYLAPEVLR SKGYNRSLDM
510 520 530 540 550
WSVGVIIYVS LSGTFPFNED EDINDQIQNA AFMYPPNPWR EISGEAIDLI
560 570 580 590 600
NNLLQVKMRK RYSVDKSLSH PWLQDYQTWL DLREFETRIG ERYITHESDD
610 620 630
ARWEIHAYTH NLVYPRHFIM APNPDDMEED P
Length:631
Mass (Da):72,149
Last modified:September 2, 2008 - v1
Checksum:i3CB35272EA4686A8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK027585 mRNA Translation: BAG51354.1
UniGeneiHs.660757
Hs.716034

Similar proteinsi

Entry informationi

Entry nameiB3KNJ2_HUMAN
AccessioniPrimary (citable) accession number: B3KNJ2
Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: September 12, 2018
This is version 77 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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