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Protein
Submitted name:

cDNA FLJ12784 fis, clone NT2RP2001898, highly similar to Type II inositol-1,4,5-trisphosphate 5-phosphatase (EC 3.1.3.36)

Gene
N/A
Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionHydrolaseSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
cDNA FLJ12784 fis, clone NT2RP2001898, highly similar to Type II inositol-1,4,5-trisphosphate 5-phosphatase (EC 3.1.3.36)Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

PTM / Processingi

Proteomic databases

PeptideAtlasiB3KMW4
PRIDEiB3KMW4

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini577 – 749Rho-GAPInterPro annotationAdd BLAST173

Phylogenomic databases

eggNOGiKOG0565 Eukaryota
KOG4270 Eukaryota
COG5411 LUCA
HOGENOMiHOG000008071
HOVERGENiHBG000070

Family and domain databases

CDDicd09093 INPP5c_INPP5B, 1 hit
Gene3Di1.10.555.10, 1 hit
2.60.40.10, 1 hit
3.60.10.10, 1 hit
InterProiView protein in InterPro
IPR036691 Endo/exonu/phosph_ase_sf
IPR005135 Endo/exonuclease/phosphatase
IPR013783 Ig-like_fold
IPR000300 IPPc
IPR037793 OCRL1/INPP5B_INPP5c
IPR008936 Rho_GTPase_activation_prot
IPR000198 RhoGAP_dom
PfamiView protein in Pfam
PF03372 Exo_endo_phos, 1 hit
PF00620 RhoGAP, 1 hit
SMARTiView protein in SMART
SM00128 IPPc, 1 hit
SM00324 RhoGAP, 1 hit
SUPFAMiSSF48350 SSF48350, 2 hits
SSF56219 SSF56219, 1 hit
PROSITEiView protein in PROSITE
PS50238 RHOGAP, 1 hit

Sequencei

Sequence statusi: Complete.

B3KMW4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSAAASSRER NTAGGSNFDG LRPNGKGVPM DQSSRGQDKP ESLQPRQNKS
60 70 80 90 100
KSEITDMVRS STITVSDKAH ILSMQKFGLR DTIVKSHLLQ KEEDYTYIQN
110 120 130 140 150
FRFFAGTYNV NGQSPKECLR LWLSNGIQAP DVYCVGFQEL DLSKEAFFFH
160 170 180 190 200
DTPKEEEWFK AVSEGLHPDA KYAKVKLIRL VGIMLLLYVK QEHAAYISEV
210 220 230 240 250
EAETVGTGIM GRMGNKGGVA IRFQFHNTSI CVVNSHLAAH IEEYERRNQD
260 270 280 290 300
YKDICSRMQF CQPDPSLPPL TISNHDVILW LGDLNYRIEE LDVEKVKKLI
310 320 330 340 350
EEKDFQMLYA YDQLKIQVAA KTVFEGFTEG ELTFQPTYKY DTGSDDWDTS
360 370 380 390 400
EKCRAPAWCD RILWKGKNIT QLSYQSHMAL KTSDHKPVSS VFDIGVRVVN
410 420 430 440 450
DELYRKTLEE IVRSLDKMEN ANIPSVSLSK REFCFQNVKY MQLKVESFTI
460 470 480 490 500
HNGQVPCHFE FINKPDEESY CKQWLNANPS RGFLLPDSDV EIDLELFVNK
510 520 530 540 550
TTATKLNSGE DKIEDILVLH LDRGKDYFLS VSGNYLPSCF GSPIHTLCYM
560 570 580 590 600
REPILDLPLE TISELTLMPV WTGDDGSQLD SPMEIPKELW MMVDYLYRNA
610 620 630 640 650
VQQEDLFQQP GLRSEFEHIR DCLDTGMIDN LSASNHSVAE ALLLFLESLP
660 670 680 690 700
EPVICYSTYH NCLECSGNYT ASKQVISTLP IFHKNVFHYL MAFLRELLKN
710 720 730 740
SAKNHLHENI LASIFGSLLL RNPAGHQKLD MTEKKKAQEF IHQFLCNPL
Length:749
Mass (Da):85,642
Last modified:September 2, 2008 - v1
Checksum:i083F0027A2664F7D
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK022846 mRNA Translation: BAG51126.1
RefSeqiNP_001284363.1, NM_001297434.1
UniGeneiHs.449942

Genome annotation databases

GeneIDi3633

Similar proteinsi

Entry informationi

Entry nameiB3KMW4_HUMAN
AccessioniPrimary (citable) accession number: B3KMW4
Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: March 28, 2018
This is version 63 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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Main funding by: National Institutes of Health