Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Flocculin

Gene

Lg-FLO1

Organism
Saccharomyces pastorianus (Lager yeast) (Saccharomyces cerevisiae x Saccharomyces eubayanus)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section indicates at which position the protein binds a given metal ion. The nature of the metal is indicated in the ‘Description’ field.<p><a href='/help/metal' target='_top'>More...</a></p>Metal bindingi134CalciumCombined sources1
Metal bindingi199Calcium; via carbonyl oxygenCombined sources1
Metal bindingi201Calcium; via carbonyl oxygenCombined sources1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

LigandCalciumCombined sources, Metal-bindingCombined sources

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
FlocculinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Lg-FLO1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiSaccharomyces pastorianus (Lager yeast) (Saccharomyces cerevisiae x Saccharomyces eubayanus)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri27292 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeSaccharomyces

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section denotes the presence of an N-terminal signal peptide.<p><a href='/help/signal' target='_top'>More...</a></p>Signal peptidei1 – 24Sequence analysisAdd BLAST24
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_500278841625 – 1300Sequence analysisAdd BLAST1276

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the PTM / Processing":/help/ptm_processing_section section describes the positions of cysteine residues participating in disulfide bonds.<p><a href='/help/disulfid' target='_top'>More...</a></p>Disulfide bondi29 ↔ 148Combined sources
<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM / Processing</a> section specifies the position and type of each covalently attached glycan group (mono-, di-, or polysaccharide).<p><a href='/help/carbohyd' target='_top'>More...</a></p>Glycosylationi108N-linked (GlcNAc...) asparagineCombined sources1
Disulfide bondi149 ↔ 236Combined sources
Glycosylationi235N-linked (GlcNAc...) asparagineCombined sources1

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
B3IUA8

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
B3IUA8

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini54 – 222PA14InterPro annotationAdd BLAST169

Keywords - Domaini

SignalSequence analysis

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR001389 Flocculin
IPR025928 Flocculin_t3_rpt
IPR037524 PA14/GLEYA
IPR011658 PA14_dom

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00624 Flocculin, 8 hits
PF13928 Flocculin_t3, 3 hits
PF07691 PA14, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00758 PA14, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS51820 PA14, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B3IUA8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MTIAHHCIFL VILAFLELLN VASGSTQACL PVGSRKNGMN VNFYKYSLQD
60 70 80 90 100
STTYSDPQYM AYKYSDTKKL GSVSGQTHLS IYYGPNTAFW NTASWSSDLF
110 120 130 140 150
GFYTTPTNVT VEMTGYFLPP QTGSYTFKFA TVDDSAILSV GGSIAFECCA
160 170 180 190 200
QEQPPITSTD FTINGIKPWD AATPTDIKGS TYMYAGYYYP IKIVYSNAKA
210 220 230 240 250
LARLPVSVVL PDGTEVNDDF EGYVYSFDDD LSQSNCTIPD PSKHTTSIVT
260 270 280 290 300
TTTELWTGTF TSTSTEMTTI TGTNGVPTDE TIIVVKTPTI ASTAITTTEP
310 320 330 340 350
WTGTFTSTST EMTTVTGTNG LPTDETIIVI RTPTTASTAI TTTEPWTGTF
360 370 380 390 400
TSTSTEMTTV TGTNGLPTDE TIIVVKTPTI ASTAITTTEP WTGTSTSTST
410 420 430 440 450
ELTTVTGTNG LPTDETIIVV RTPTTASTII TTTEPWTGTF TSTSTEMTTV
460 470 480 490 500
TGTNGQPTDE TVIVVKTPTT ANTIVTTTKP WTGTFTSTST EMTTVTGTNG
510 520 530 540 550
QPTDETVIVI RTPTSEGLIS TTTEPWTGTF TSTSTEVTTI TGTNGQPTDE
560 570 580 590 600
TVIVIRTPTS EGLVTTTTEP WTGTFTSTST GMTTITGTNG LPTDETVIVV
610 620 630 640 650
KTPTTAISSS LSLSSSGQIT SSITSSRPII TPFYPSNGTS VISSSDTSSS
660 670 680 690 700
DTSSLVTSSL VTSSLVTSSV ISSSVTSSLV TSSVISSSVT SSLVTSSVIS
710 720 730 740 750
SSVTSSLFTS SPVISSSVIS SSTTTSTSIF FESSKSSVIP TSSSTSGSSE
760 770 780 790 800
SKTSSASSSS SSSSISSESP KSTYSSSSLP PVTSATTSQE TASSLPPVTS
810 820 830 840 850
VTTSQEITSS LPPVISTTTS QETASSLPPV TSATTSQETA SSLPPVTSVT
860 870 880 890 900
TSQEITSSLP PVTSVTTSQE ITSSLPPVTS ATTSQEITSS LPPVTSATTS
910 920 930 940 950
QETASSLPPV TSAATSQETA SSLPPVTSVT TSQEITSSLP PVTSVTTSQE
960 970 980 990 1000
ITSSLPPVTS VTTSQEITSS LPPVTSATTS QETASSLPPA TTTKTSEQTT
1010 1020 1030 1040 1050
LVTVTSCESH VCTESISSAI VSTATVTVSG VTTEYTTWCP ISTTEITKQT
1060 1070 1080 1090 1100
TETTKQTKGT TKQTKGTTEQ TTETTKQTTV VTISSCESDI CSKTASPAIV
1110 1120 1130 1140 1150
STSTATINDV TTEYTTWCPI STTESKQQTT LVTVTSCESG VCSETASPAI
1160 1170 1180 1190 1200
VSTATATVND VVTVYPTWRP QTTNEQSVSS KMNSATSETT TNTGAAETKT
1210 1220 1230 1240 1250
AVTSSLSRFN HAETQTASAT DVIGHSSSVV SVSETGNTKG LITSELSTMS
1260 1270 1280 1290 1300
QQPRSTPAST MVGSSTASLE ISTYVGIANG LLTNNGISVF ISTVLLAIVW
Length:1,300
Mass (Da):134,697
Last modified:September 2, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3345C5106C434DA0
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AB288349 Genomic DNA Translation: BAG49462.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AB288349 Genomic DNA Translation: BAG49462.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4GQ7X-ray2.53A26-245[»]
ProteinModelPortaliB3IUA8
SMRiB3IUA8
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

InterProiView protein in InterPro
IPR001389 Flocculin
IPR025928 Flocculin_t3_rpt
IPR037524 PA14/GLEYA
IPR011658 PA14_dom
PfamiView protein in Pfam
PF00624 Flocculin, 8 hits
PF13928 Flocculin_t3, 3 hits
PF07691 PA14, 1 hit
SMARTiView protein in SMART
SM00758 PA14, 1 hit
PROSITEiView protein in PROSITE
PS51820 PA14, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB3IUA8_SACPS
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B3IUA8
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: September 2, 2008
Last sequence update: September 2, 2008
Last modified: December 5, 2018
This is version 41 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again