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Entry version 99 (07 Apr 2021)
Sequence version 1 (22 Jul 2008)
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Protein
Submitted name:

Ketose-bisphosphate aldolase class-II family protein

Gene

At1g18270

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Unreviewed-Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionKinaseARBA annotation, OxidoreductaseARBA annotation, Transferase
Biological processCarbohydrate metabolismARBA annotation
LigandATP-bindingARBA annotation, Nucleotide-binding

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Ketose-bisphosphate aldolase class-II family proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:At1g18270Imported
ORF Names:T10O22.24Imported, T10O22_24Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiArabidopsis thaliana (Mouse-ear cress)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri3702 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliopsidaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000006548 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 1

Organism-specific databases

Arabidopsis Information Portal

More...
Araporti
AT1G18270

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Proteomic databases

PRoteomics IDEntifications database

More...
PRIDEi
B3H739

ProteomicsDB: a multi-organism proteome resource

More...
ProteomicsDBi
199770

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
B3H739, baseline and differential

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
B3H739

Database of comparative protein structure models

More...
ModBasei
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini5 – 163NAD_binding_2InterPro annotationAdd BLAST159
Domaini170 – 287NAD_binding_11InterPro annotationAdd BLAST118
Domaini324 – 482NAD_binding_2InterPro annotationAdd BLAST159
Domaini489 – 609NAD_binding_11InterPro annotationAdd BLAST121
Domaini656 – 894SBD_NInterPro annotationAdd BLAST239
Domaini918 – 1084NBD_CInterPro annotationAdd BLAST167

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the four-carbon acid sugar kinase family.ARBA annotation

Phylogenomic databases

Database for complete collections of gene phylogenies

More...
PhylomeDBi
B3H739

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00947, TBP_aldolase_IIB, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.10.1040.10, 2 hits
3.20.20.70, 1 hit
3.40.50.10840, 1 hit
3.40.980.20, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR002204, 3-OH-isobutyrate_DH-rel_CS
IPR037051, 4-carb_acid_sugar_kinase_N_sf
IPR008927, 6-PGluconate_DH-like_C_sf
IPR013328, 6PGD_dom2
IPR006115, 6PGDH_NADP-bd
IPR013785, Aldolase_TIM
IPR010737, DUF1537
IPR000771, FBA_II
IPR036291, NAD(P)-bd_dom_sf
IPR029154, NADP-bd
IPR031475, NBD_C
IPR042213, NBD_C_sf

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF01116, F_bP_aldolase, 1 hit
PF14833, NAD_binding_11, 2 hits
PF03446, NAD_binding_2, 2 hits
PF17042, NBD_C, 1 hit
PF07005, SBD_N, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48179, SSF48179, 2 hits
SSF51735, SSF51735, 2 hits

TIGRFAMs; a protein family database

More...
TIGRFAMsi
TIGR00167, cbbA, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00895, 3_HYDROXYISOBUT_DH, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 3 potential isoforms that are computationally mapped.Show allAlign All

B3H739-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSGVVGFVGL DSFSFELASS LLRSGFKVQA FEISTELVEK FIELGGHKCD
60 70 80 90 100
SPADVGKAAA AAVVVVLSHP DQIQDVIFGD EGVMKGLQKD AVLLLSSTIS
110 120 130 140 150
TLQLQKLEKQ LTEKREQIFV VDAYVLKGMS ELLDGKLMII ASGRSDSITR
160 170 180 190 200
AQPYLTAMCQ NLYTFEGEIG AGSKVKMVNE LLEGIHLVAA VEAISLGSQA
210 220 230 240 250
GVHPWILYDI ISNAAGNSWI YKNHIPLLLK DDIEGRFLDV LSQNLAIVED
260 270 280 290 300
KAKSLPFPVP LLAVARQQLI SGISQMQGDD TATSLAKISE KVLGVGILEA
310 320 330 340 350
ANRELYKPED LAKEITTQAK PVNRIGFIGL GAMGFGMAAH LLKSNFSVCG
360 370 380 390 400
YDVYKPTLVR FENAGGLAAN SPAEVTKDVD VLVIMVTNEV QAEDVLYGHL
410 420 430 440 450
GAVEAIPSGA TVVLASTVSP AFVSQLERRL ENEGKDLKLV DAPVSGGVKR
460 470 480 490 500
AAMGELTIMA SGTDEALKSA GLVLSALSEK LYVIKGGCGA GSGVKMVNQL
510 520 530 540 550
LAGVHIASAA EAMAFGARLG LNTRKLFNVI SNSGGTSWMF ENRVPHMLDN
560 570 580 590 600
DYTPYSALDI FVKDLGIVTR EGSSRKVPLH ISTVAHQLFL AGSAAGWGRI
610 620 630 640 650
DDAGVVKVYE TLAGIKVEGR LPVLKKQDLL KSLPAEWPSD PTTDIHRLNM
660 670 680 690 700
GNSKTLVVLD DDPTGTQTVH DVEVLTEWSV ESISEQFRKK PACFFILTNS
710 720 730 740 750
RSLSPEKASE LIKDICSNLC AASKEVGNAD YTIVLRGDST LRGHFPQEAD
760 770 780 790 800
AAVSILGEMD AWIICPFFLQ GGRYTIDDVH YVADSDRLVP AGETEFAKDA
810 820 830 840 850
SFGYKSSNLR EWVEEKTAGV IPANSVQSIS IQLLRKGGPD AVCEFLCSLK
860 870 880 890 900
KGSTCIVNAA SERDMAVFAA GMIQAELKGR SFLCRTAASF VSALIGIIPK
910 920 930 940 950
DPVLPKDFES NKESSGALIV VGSYVPKTTK QVEELQSQHN QNLRSIEISV
960 970 980 990 1000
EKVALKSSEV RDEEIRRAVE MADAFLRAGR ETLIMSSREL ITGKTSSESL
1010 1020 1030 1040 1050
DINSKVSSAL VEVVSQISTR PRYILAKGGI TSSDTATKAL KARRALVIGQ
1060 1070 1080 1090 1100
ALAGVPVWKL GPESRHPGVP YIVFPGNVGN STALAEVVKS WSVVAGRSTK
1110 1120 1130 1140 1150
ELLLNAEKGG YAVGAFNVYN LEGIEAVVAA AEEENSPAIL QVHPGAFKQG
1160 1170 1180 1190 1200
GIPLVSCCIS AAEQARVPIS VHFDHGTTKH ELLEALELGL DSVMVDGSHL
1210 1220 1230 1240 1250
SFTENLSYTK SITELARSKN IMVEAELGRL SGTEDGLTVE DYEAKLTNVN
1260 1270 1280 1290 1300
QAQEFMETGI DALAVCIGNV HGKYPKSGPN LKLDLLKELH ALSSKKGVFL
1310 1320 1330 1340 1350
VLHGASGLSE NLIKECIENG VRKFNVNTEV RTAYMEALSS GKKTDIVDVM
1360 1370
SATKAAMKAV IADKIRLFGS AGKA
Length:1,374
Mass (Da):147,114
Last modified:July 22, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i3B18BC3345D6DAF4
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 3 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
F4IAP5F4IAP5_ARATH
Ketose-bisphosphate aldolase class-...
At1g18270, T10O22.24, T10O22_24
1,393Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q8VYC5Q8VYC5_ARATH
Ketose-bisphosphate aldolase class-...
At1g18270, T10O22.24, T10O22_24
1,373Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A1P8AVD8A0A1P8AVD8_ARATH
Ketose-bisphosphate aldolase class-...
At1g18270, T10O22.24, T10O22_24
1,314Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CP002684 Genomic DNA Translation: AEE29695.1

NCBI Reference Sequences

More...
RefSeqi
NP_001117303.1, NM_001123831.1

Genome annotation databases

Ensembl plant genome annotation project

More...
EnsemblPlantsi
AT1G18270.2; AT1G18270.2; AT1G18270

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
838407

Gramene; a comparative resource for plants

More...
Gramenei
AT1G18270.2; AT1G18270.2; AT1G18270

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ath:AT1G18270

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP002684 Genomic DNA Translation: AEE29695.1
RefSeqiNP_001117303.1, NM_001123831.1

3D structure databases

SMRiB3H739
ModBaseiSearch...

Proteomic databases

PRIDEiB3H739
ProteomicsDBi199770

Genome annotation databases

EnsemblPlantsiAT1G18270.2; AT1G18270.2; AT1G18270
GeneIDi838407
GrameneiAT1G18270.2; AT1G18270.2; AT1G18270
KEGGiath:AT1G18270

Organism-specific databases

AraportiAT1G18270

Phylogenomic databases

PhylomeDBiB3H739

Gene expression databases

ExpressionAtlasiB3H739, baseline and differential

Family and domain databases

CDDicd00947, TBP_aldolase_IIB, 1 hit
Gene3Di1.10.1040.10, 2 hits
3.20.20.70, 1 hit
3.40.50.10840, 1 hit
3.40.980.20, 1 hit
InterProiView protein in InterPro
IPR002204, 3-OH-isobutyrate_DH-rel_CS
IPR037051, 4-carb_acid_sugar_kinase_N_sf
IPR008927, 6-PGluconate_DH-like_C_sf
IPR013328, 6PGD_dom2
IPR006115, 6PGDH_NADP-bd
IPR013785, Aldolase_TIM
IPR010737, DUF1537
IPR000771, FBA_II
IPR036291, NAD(P)-bd_dom_sf
IPR029154, NADP-bd
IPR031475, NBD_C
IPR042213, NBD_C_sf
PfamiView protein in Pfam
PF01116, F_bP_aldolase, 1 hit
PF14833, NAD_binding_11, 2 hits
PF03446, NAD_binding_2, 2 hits
PF17042, NBD_C, 1 hit
PF07005, SBD_N, 1 hit
SUPFAMiSSF48179, SSF48179, 2 hits
SSF51735, SSF51735, 2 hits
TIGRFAMsiTIGR00167, cbbA, 1 hit
PROSITEiView protein in PROSITE
PS00895, 3_HYDROXYISOBUT_DH, 1 hit

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB3H739_ARATH
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B3H739
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: April 7, 2021
This is version 99 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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