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Entry version 25 (29 Sep 2021)
Sequence version 1 (22 Jul 2008)
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Protein
Submitted name:

Trimeric autotransporter adhesin

Gene

cha

Organism
Haemophilus sp. 1595
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Protein inferred from homologyi <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transportARBA annotation, Transport

Protein family/group databases

Transport Classification Database

More...
TCDBi
1.B.40.1.5, the autotransporter-2 (at-2) family

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Trimeric autotransporter adhesinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:chaImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiHaemophilus sp. 1595Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri502960 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaGammaproteobacteriaPasteurellalesPasteurellaceaeHaemophilus

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Keywords - Cellular componenti

Cell outer membraneARBA annotation, Membrane

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 24ESPRInterPro annotationAdd BLAST24
Domaini420 – 464YadA_stalkInterPro annotationAdd BLAST45
Domaini474 – 500YadA_headInterPro annotationAdd BLAST27
Domaini698 – 740YadA_stalkInterPro annotationAdd BLAST43
Domaini804 – 830YadA_headInterPro annotationAdd BLAST27
Domaini1100 – 1140YadA_stalkInterPro annotationAdd BLAST41
Domaini1455 – 1481YadA_headInterPro annotationAdd BLAST27
Domaini1499 – 1535YadA_stalkInterPro annotationAdd BLAST37
Domaini1550 – 1610YadA_anchorInterPro annotationAdd BLAST61

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni463 – 485DisorderedSequence analysisAdd BLAST23

<p>This subsection of the 'Family and domains' section provides information about the sequence similarity with other proteins.<p><a href='/help/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesi

Belongs to the autotransporter-2 (AT-2) (TC 1.B.40) family. [View classification]ARBA annotation

Keywords - Domaini

SignalARBA annotation, TransmembraneARBA annotation

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.150.10.10, 6 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR008640, Adhesin_Head_dom
IPR008635, Coiled_stalk_dom
IPR024973, ESPR
IPR011049, Serralysin-like_metalloprot_C
IPR005594, YadA_C

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF13018, ESPR, 1 hit
PF03895, YadA_anchor, 1 hit
PF05658, YadA_head, 3 hits
PF05662, YadA_stalk, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF101967, SSF101967, 6 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B3FNS7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MNKIFKIIWN KTTQRLEVVS ELAKSQGKAT VSTDKRAEVT SAVDFKKSTL
60 70 80 90 100
FRAISLALGL SAISLPAGAA SFTDNYTEGW STAWGAGNKY GERISAKDFP
110 120 130 140 150
IVVGRNNNLA PKNSRAEGNP ASATVMGRDN NITSGLAFTV FGDRNQLNTG
160 170 180 190 200
NVSTVVGIYN RITGGKTNKY LTVLGNNIYA QNPTESGLYI GNNLEANASP
210 220 230 240 250
IAIGNNVYSE IGGSVIGHNA SVRARHANGG GFLTQDSGFA VGDNIKGYGN
260 270 280 290 300
HVFFGRGINL EGGKIANVAT ADNKKGVYVG QDITSKGAKE GVLLGTNLTS
310 320 330 340 350
NDNVAHYSVG VGSNINMTGN AENATAVGQH ITLNGKKSVA VGHNITVSAE
360 370 380 390 400
DSVSLGSGSR AAKQGDVVLG AGSATTANTN SNLSGWTVSG TNLTASYATS
410 420 430 440 450
VKQTAGKGVV SVGSDSVKRQ IKNVATGDVS ATSTDAVNGA QLYALSTKIG
460 470 480 490 500
ESSSEYFHVN SNKTGNKGKT ATGATGSNSV AVGPNAKASS ESGIAIGDES
510 520 530 540 550
KAAGSQGALA VGQNANAAHN NATAIGRNSV ANGTDSVAVG LNAIASGSSA
560 570 580 590 600
IAMGKSANSK NNSTVALGQE ANATGIAGTA LGYRSQSTGD WTVAAGPDAR
610 620 630 640 650
ALKNFAVAVG NNANATEVNA VAVGKSSTAG KDSSLALGNN ATANAASGDI
660 670 680 690 700
ALGASSVTAT ANNITDFTIG TTKVSDSFVK AKGNQGVVSV GSTTVKRQIQ
710 720 730 740 750
NVGAGDVSAI STDAINGSQL YHVATALNTL ATDAKTAAVA ADEKAGAAST
760 770 780 790 800
AASTAASKAD AAQTTANKAK TAADGAAAAV NNSYLHVNSS KTGNRAALNE
810 820 830 840 850
TANATGENSI ALGPNATASG TSSIAIGDEA SSTASGTVSI GQNAINRANN
860 870 880 890 900
STVIGRNAQV TKDSTDSVAI GLGSIVTSTS ATAIGKNANA SGASSISIGQ
910 920 930 940 950
NTLTKNSATI AVGYNITAVA NNATAVGSYT NATGEASVAL GYKIEAGSWA
960 970 980 990 1000
TAVGSNTKAT GSTSAAFGNN VIASGESSLA LGYQSKATAN WAVSVGGGSQ
1010 1020 1030 1040 1050
ANGVNSTSVG RGALAAGEQA TAIGAVANAG KDKSLALGRG ATANTAEGDV
1060 1070 1080 1090 1100
AIGDSSLTAE VNPISELTIG NTKVSDSFQK ATKNGVVSVG RNDKTRIKRQ
1110 1120 1130 1140 1150
IQNVGAGDVS ATSTDAINGS QLYHVATALN TLATDAKTAA AVADSKATVA
1160 1170 1180 1190 1200
STAASTADSK ATVASTAAAV ADSKATVAST AASTADSKAT VASTAAAVAD
1210 1220 1230 1240 1250
SKATVASTAA STADSKATVA STAAAVADSK ATVASTAAST ADSKATVAST
1260 1270 1280 1290 1300
AAAVADSKAT VASTAASTAD SKATVASTAA AVADSKATVA STAASTADSK
1310 1320 1330 1340 1350
ATVASTAAAV ADSKATVAST AASTADSKAT VASTAAAVAD SKATVASTAA
1360 1370 1380 1390 1400
STADSKATVA STAAAVADSK ATVASTAAST ADSKATVAST AAAVADSKAE
1410 1420 1430 1440 1450
AVKETINRSG LEIDGQNTKI GSGSTYAGGS NATAIGGSAK ATAENTTAVG
1460 1470 1480 1490 1500
QGSEATAKGA TAIGQGAKAT AENAVAIGTG SVAAEANTVS IGSQGNERRI
1510 1520 1530 1540 1550
TNVAAGVNPT DAANVGQVNA VENRINNKLG KFDKKLRSGV ASAVAVANIP
1560 1570 1580 1590 1600
QVTIPGANMV ALGVGNYKGQ SAVAVGYSRA SDSNRVIIKM TAGASTQRDY
1610
TFGAGIGYQW
Length:1,610
Mass (Da):157,035
Last modified:July 22, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iB575B3B9BFE0839E
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
EU309721 Genomic DNA Translation: ACA04477.1

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
EU309721 Genomic DNA Translation: ACA04477.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein family/group databases

TCDBi1.B.40.1.5, the autotransporter-2 (at-2) family

Family and domain databases

Gene3Di2.150.10.10, 6 hits
InterProiView protein in InterPro
IPR008640, Adhesin_Head_dom
IPR008635, Coiled_stalk_dom
IPR024973, ESPR
IPR011049, Serralysin-like_metalloprot_C
IPR005594, YadA_C
PfamiView protein in Pfam
PF13018, ESPR, 1 hit
PF03895, YadA_anchor, 1 hit
PF05658, YadA_head, 3 hits
PF05662, YadA_stalk, 4 hits
SUPFAMiSSF101967, SSF101967, 6 hits

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB3FNS7_9PAST
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B3FNS7
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: September 29, 2021
This is version 25 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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