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Protein
Submitted name:

WD repeat and SOCS box-containing 1

Gene

Wsb1

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.SAAS annotation
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-RNO-8951664 Neddylation
R-RNO-983168 Antigen processing: Ubiquitination & Proteasome degradation
UniPathwayiUPA00143

Names & Taxonomyi

Protein namesi
Submitted name:
WD repeat and SOCS box-containing 1Imported
Submitted name:
WD repeat and SOCS box-containing 1, isoform CRA_bImported
Gene namesi
Name:Wsb1Imported
ORF Names:rCG_32954Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 10

Organism-specific databases

RGDi1307835 Wsb1

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSRNOG00000012929

Interactioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000017949

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini136 – 388WD_REPEATS_REGIONInterPro annotationAdd BLAST253
Repeati136 – 165WDPROSITE-ProRule annotationAdd BLAST30
Repeati166 – 208WDPROSITE-ProRule annotationAdd BLAST43
Repeati210 – 251WDPROSITE-ProRule annotationAdd BLAST42
Repeati252 – 293WDPROSITE-ProRule annotationAdd BLAST42
Repeati314 – 340WDPROSITE-ProRule annotationAdd BLAST27
Repeati358 – 378WDPROSITE-ProRule annotationAdd BLAST21
Domaini377 – 421SOCS boxInterPro annotationAdd BLAST45

Keywords - Domaini

WD repeatPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiENOG410KD26 Eukaryota
ENOG411010D LUCA
GeneTreeiENSGT00890000139406
HOGENOMiHOG000063727
HOVERGENiHBG034543
KOiK10341
OMAiGHHNDVV
OrthoDBiEOG091G06GY
TreeFamiTF329216

Family and domain databases

Gene3Di2.130.10.10, 2 hits
InterProiView protein in InterPro
IPR020472 G-protein_beta_WD-40_rep
IPR001496 SOCS_box
IPR036036 SOCS_box-like_dom_sf
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf
PfamiView protein in Pfam
PF07525 SOCS_box, 1 hit
PF00400 WD40, 5 hits
PRINTSiPR00320 GPROTEINBRPT
SMARTiView protein in SMART
SM00253 SOCS, 1 hit
SM00969 SOCS_box, 1 hit
SM00320 WD40, 6 hits
SUPFAMiSSF158235 SSF158235, 1 hit
SSF50978 SSF50978, 1 hit
PROSITEiView protein in PROSITE
PS50225 SOCS, 1 hit
PS00678 WD_REPEATS_1, 2 hits
PS50082 WD_REPEATS_2, 6 hits
PS50294 WD_REPEATS_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

B3DM89-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MASFPPRVNE KEIVRSRTIG ELLAPAAPFD KKCGGENWTV AFAPDGSYFA
60 70 80 90 100
WSQGYRIVKL VPWSQCLKNF LLHGSKNVTN SSCLKLARQN SNGGQKNKPR
110 120 130 140 150
EHIIDCGDIV WSLAFGSSVP EKQSRCVNIE WHRFRFGQDQ LLLATGLNNG
160 170 180 190 200
RIKIWDVYTG KLLLNLVDHI EVVRDLTFAP DGSLLLVSAS RDKTLRVWDL
210 220 230 240 250
KDDGNMVKVL RGHQNWVYSC AFSPDCSMLC SVGASKAVFL WNMDKYTMIR
260 270 280 290 300
RLEGHHHDVV ACDFSPDGAL LATASYDTRV YVWDPHIGDT LMEFGHLFPP
310 320 330 340 350
PTPIFAGGAN DRWVRAVSFS HDGLHVASLA DDKMVRFWSI GDDCPVQVAP
360 370 380 390 400
LSNGLCCAFS TDGSVLAAGT HDGSVYFWAT PRQVSSLQHL CRMSIRRVMP
410 420
TQEVQKLPVP SKMLEFLSYR V
Length:421
Mass (Da):47,051
Last modified:July 22, 2008 - v1
Checksum:i6355E23FDDEEB56C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07030085 Genomic DNA No translation available.
BC167746 mRNA Translation: AAI67746.1
CH473948 Genomic DNA Translation: EDM05388.1
RefSeqiNP_001036026.1, NM_001042561.1
UniGeneiRn.18535

Genome annotation databases

EnsembliENSRNOT00000017949; ENSRNOP00000017949; ENSRNOG00000012929
GeneIDi303336
KEGGirno:303336

Similar proteinsi

Entry informationi

Entry nameiB3DM89_RAT
AccessioniPrimary (citable) accession number: B3DM89
Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: July 18, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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