Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Cbl protein

Gene

cbl

Organism
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
Cbl proteinImported
Gene namesi
Name:cblImported
OrganismiXenopus tropicalis (Western clawed frog) (Silurana tropicalis)Imported
Taxonomic identifieri8364 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiAmphibiaBatrachiaAnuraPipoideaPipidaeXenopodinaeXenopusSilurana

Organism-specific databases

XenbaseiXB-GENE-6258452 cbl

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

ProteinModelPortaliB3DLI0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini29 – 333Cbl-PTBInterPro annotationAdd BLAST305
Domaini363 – 402RING-typeInterPro annotationAdd BLAST40
Domaini838 – 877UBAInterPro annotationAdd BLAST40

Keywords - Domaini

Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG1785 Eukaryota
ENOG410YDNH LUCA
HOVERGENiHBG005255
KOiK04707
OrthoDBiEOG091G0GPE

Family and domain databases

CDDicd16709 RING-HC_Cbl-b, 1 hit
cd09920 SH2_Cbl-b_TKB, 1 hit
Gene3Di1.20.930.20, 1 hit
3.30.40.10, 1 hit
3.30.505.10, 1 hit
InterProiView protein in InterPro
IPR024162 Adaptor_Cbl
IPR014741 Adaptor_Cbl_EF_hand-like
IPR036537 Adaptor_Cbl_N_dom_sf
IPR003153 Adaptor_Cbl_N_hlx
IPR014742 Adaptor_Cbl_SH2-like
IPR039520 CBL-B_RING-HC
IPR024159 Cbl_PTB
IPR011992 EF-hand-dom_pair
IPR036860 SH2_dom_sf
IPR015940 UBA
IPR009060 UBA-like_sf
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS
PANTHERiPTHR23007 PTHR23007, 1 hit
PfamiView protein in Pfam
PF02262 Cbl_N, 1 hit
PF02761 Cbl_N2, 1 hit
PF02762 Cbl_N3, 1 hit
PF00627 UBA, 1 hit
SMARTiView protein in SMART
SM00184 RING, 1 hit
SM00165 UBA, 1 hit
SUPFAMiSSF46934 SSF46934, 1 hit
SSF47473 SSF47473, 1 hit
SSF47668 SSF47668, 1 hit
SSF55550 SSF55550, 1 hit
PROSITEiView protein in PROSITE
PS51506 CBL_PTB, 1 hit
PS50030 UBA, 1 hit
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit

Sequencei

Sequence statusi: Complete.

B3DLI0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATNLRKGGG LIGLVKDAFQ PHHHHPTAQP GAVDRKTVEK CWKLMDKVVR
60 70 80 90 100
LCQNQRLALK NSPPYILDLL PDTYQHLRTI MSRYEGKMEI LGENEYFRVF
110 120 130 140 150
MENLLKKTKQ TISLFKEGKE RMYEENSQPR RNLTKLSLIF SHMLAELKAI
160 170 180 190 200
FPNGQFQGDS FRITKADAAE FWRKAFGEKT IVPWKIFRLA LHDVHPISSG
210 220 230 240 250
LEAMALKSTI DLTCNDYISV FEFDIFTRLF QPWSSLLRNW NSLAVTHPGY
260 270 280 290 300
MAFLTYDEVK ARLQKFIHKP GSYIFRLSCT RLGQWAIGYV TGDGNILQTI
310 320 330 340 350
PHNKPLFQAL IDGFREGFYL FPDGRNQNPD LTGLCEPTPQ DHIKVTQEQY
360 370 380 390 400
ELYCEMGSTF QLCKICAEND KDVKIEPCGH LMCTSCLTSW QESEGQGCPF
410 420 430 440 450
CRCEIKGTEP IVVDPFDPRG GGMAELLRHC MDGTPSPCYD DDDDDSGNDS
460 470 480 490 500
IFVMKELAGA KVERPPSPLS ATPQASLPPV PPRLDLLPQR APNQSGACSP
510 520 530 540 550
ATSSKASSSS HHKDKPLPVP PTLRDLPPPP PPDRPHSMPC ESRPQRRPLP
560 570 580 590 600
STPAEKPLPL PTNRPGETWH PRAVPKAPAS NLTPGDPWTG GRELTNRHSL
610 620 630 640 650
PFTLPSHIDE RRDRHGSTQS LDNTGISATT ELFGGLDNDD AKMKPSSSAN
660 670 680 690 700
AIYSLATRPF PVSKPPTGDH VDSGDESEYM CPSSRPLIPA AVPKSEARRP
710 720 730 740 750
LETLPGLRPP DQQTERESYE TMYNIQCQAT NPVVVEPSRE EETNSAIANN
760 770 780 790 800
GPENDDNEED GYDIPKPHLP MAPARRTMSD APNATPAFCS GAIGRDSGAG
810 820 830 840 850
LLESSQVPER PPKPFPRRMN SERRSVVGGG SGDAPPAPLS SEIESLLSQG
860 870 880
YSQQDVNKAL LIAHNNIEMA RNILREFVSI PSPAHVAT
Length:888
Mass (Da):98,562
Last modified:July 22, 2008 - v1
Checksum:iFEE51C20A0F5847E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC167455 mRNA Translation: AAI67455.1
RefSeqiNP_001122110.1, NM_001128638.1
UniGeneiStr.1437

Genome annotation databases

GeneIDi594900
KEGGixtr:594900

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC167455 mRNA Translation: AAI67455.1
RefSeqiNP_001122110.1, NM_001128638.1
UniGeneiStr.1437

3D structure databases

ProteinModelPortaliB3DLI0
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi594900
KEGGixtr:594900

Organism-specific databases

CTDi867
XenbaseiXB-GENE-6258452 cbl

Phylogenomic databases

eggNOGiKOG1785 Eukaryota
ENOG410YDNH LUCA
HOVERGENiHBG005255
KOiK04707
OrthoDBiEOG091G0GPE

Family and domain databases

CDDicd16709 RING-HC_Cbl-b, 1 hit
cd09920 SH2_Cbl-b_TKB, 1 hit
Gene3Di1.20.930.20, 1 hit
3.30.40.10, 1 hit
3.30.505.10, 1 hit
InterProiView protein in InterPro
IPR024162 Adaptor_Cbl
IPR014741 Adaptor_Cbl_EF_hand-like
IPR036537 Adaptor_Cbl_N_dom_sf
IPR003153 Adaptor_Cbl_N_hlx
IPR014742 Adaptor_Cbl_SH2-like
IPR039520 CBL-B_RING-HC
IPR024159 Cbl_PTB
IPR011992 EF-hand-dom_pair
IPR036860 SH2_dom_sf
IPR015940 UBA
IPR009060 UBA-like_sf
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS
PANTHERiPTHR23007 PTHR23007, 1 hit
PfamiView protein in Pfam
PF02262 Cbl_N, 1 hit
PF02761 Cbl_N2, 1 hit
PF02762 Cbl_N3, 1 hit
PF00627 UBA, 1 hit
SMARTiView protein in SMART
SM00184 RING, 1 hit
SM00165 UBA, 1 hit
SUPFAMiSSF46934 SSF46934, 1 hit
SSF47473 SSF47473, 1 hit
SSF47668 SSF47668, 1 hit
SSF55550 SSF55550, 1 hit
PROSITEiView protein in PROSITE
PS51506 CBL_PTB, 1 hit
PS50030 UBA, 1 hit
PS00518 ZF_RING_1, 1 hit
PS50089 ZF_RING_2, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB3DLI0_XENTR
AccessioniPrimary (citable) accession number: B3DLI0
Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: November 7, 2018
This is version 68 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again