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Entry version 75 (05 Jun 2019)
Sequence version 1 (22 Jul 2008)
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Protein
Submitted name:

Period circadian clock 1b

Gene

per1b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:4 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Period circadian clock 1bImported
Submitted name:
Period homolog 1b (Drosophila)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:per1bImported
Synonyms:per4Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000437 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 7

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-040419-1 per1b

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSDARG00000012499 Expressed in 16 organ(s), highest expression level in pharyngeal gill

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRING: functional protein association networks

More...
STRINGi
7955.ENSDARP00000007258

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini403 – 446PASInterPro annotationAdd BLAST44

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni1 – 164DisorderedSequence analysisAdd BLAST164
Regioni537 – 571DisorderedSequence analysisAdd BLAST35
Regioni594 – 614DisorderedSequence analysisAdd BLAST21
Regioni675 – 708DisorderedSequence analysisAdd BLAST34
Regioni774 – 804DisorderedSequence analysisAdd BLAST31
Regioni842 – 933DisorderedSequence analysisAdd BLAST92
Regioni1022 – 1061DisorderedSequence analysisAdd BLAST40
Regioni1078 – 1132DisorderedSequence analysisAdd BLAST55
Regioni1146 – 1217DisorderedSequence analysisAdd BLAST72
Regioni1339 – 1361DisorderedSequence analysisAdd BLAST23
Regioni1377 – 1398DisorderedSequence analysisAdd BLAST22

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi30 – 49PolarSequence analysisAdd BLAST20
Compositional biasi59 – 78PolarSequence analysisAdd BLAST20
Compositional biasi87 – 164PolarSequence analysisAdd BLAST78
Compositional biasi537 – 565PolarSequence analysisAdd BLAST29
Compositional biasi675 – 694PolarSequence analysisAdd BLAST20
Compositional biasi914 – 933PolarSequence analysisAdd BLAST20
Compositional biasi1022 – 1045PolarSequence analysisAdd BLAST24
Compositional biasi1146 – 1207PolarSequence analysisAdd BLAST62
Compositional biasi1340 – 1354PolyampholyteSequence analysisAdd BLAST15

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3753 Eukaryota
ENOG410Y118 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000159217

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
HOG000231111

Identification of Orthologs from Complete Genome Data

More...
OMAi
PGERGCH

TreeFam database of animal gene trees

More...
TreeFami
TF318445

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00130 PAS, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR000014 PAS
IPR035965 PAS-like_dom_sf
IPR013655 PAS_fold_3
IPR022728 Period_circadian-like_C

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF08447 PAS_3, 1 hit
PF12114 Period_C, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00091 PAS, 2 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF55785 SSF55785, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50112 PAS, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B3DK47-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MSDDNSDSAP SNDADSGAGG IEKKAGRSCG MSESSPSSNP ESSGSGGLSG
60 70 80 90 100
PKGSAGGNRG VNSDDTDGLS SGNDSGERES EGGMQRGSGS RGRQSNRSYQ
110 120 130 140 150
SSSSQNGKDS AMGMETTESN KSSNSHSPSP PSSSLAYSLL SASSEQDPPS
160 170 180 190 200
TSGCSSDQSA RVQTQKELMR ALNELKIRLP PERKMKGRSS TLNALKYALS
210 220 230 240 250
CVRQVRANQE YYHQWNVEEC HGCSLDLSTF TVEELDNITS EYTLKNTDTF
260 270 280 290 300
TMAVSFLSGK VVYISPQGSS LLRSKPERLH GVLFSELLAP QDVSTFYSNT
310 320 330 340 350
APCKLPAWAS CIGSVSPPME CTQEKSMFCR ISGDVSSSSD VRYYPFRLTP
360 370 380 390 400
YLLTLRDSDM AFPQPCCLLI AERVHSGYEA PRIPLDKRIF TTSHTPSCVF
410 420 430 440 450
QEVDERAVPL LGYLPQDLVG TPVLLCIHPD DRHIMVAIHK KILQFAGQPF
460 470 480 490 500
EHSPLRMCAR NGEYMTIDTS WSSFINPWSR KVAFIVGRHK VRTSPLNEDV
510 520 530 540 550
FTPPRGLEER ALTPDIVQLS EQIHRLLVQP VHCGSSQGYG SLPSNGSHEH
560 570 580 590 600
QPSAASSSDS SGPGVEDPSQ LHKPMTFQQI CKDVHMVKTS GQQVFIDSRN
610 620 630 640 650
RPPPKKHSTA GALKAGESAE VCRSLIPCAA PPSKSSAPSL IVQKEPPTTF
660 670 680 690 700
SYQQINCLDS IIRYLESCNV PNTVKRKCGS SSCTASSTSD DDKQQEAPGN
710 720 730 740 750
AKGPSVSLVD DSALLPPLAL HNKAESVASV TSQCSFSSTI VHVGDKKPPE
760 770 780 790 800
SDIVMEEAPP TPNIALPVTQ PQVPPMATPS LPLSPAPDRD AGRRGGPGAS
810 820 830 840 850
AGGERLGLTK EVLSAHTQQE EQNFMCRFGD LSKLRVFDPT SAVRRRPNAP
860 870 880 890 900
LSRGVRCSRD YPAAGSSGRR RGRGGKRLKH QESSEQTGSC SPAGPIRGLL
910 920 930 940 950
PGVPALGRPS NPSIPMGPTA SSSSWPTSGS QASVPNVQYP PTVLPFYPVY
960 970 980 990 1000
PPISHPVSDP SMQSGLRFPL QNSQMAPPMV PPMMALVLPN YMFPQPSVGM
1010 1020 1030 1040 1050
AQPFFSPNSA FPFAAANMGS PAPCQIQTPI QRAHSRSSTP HSYSQRENGA
1060 1070 1080 1090 1100
EREGAESPLF QSRCSSPLNL LQLEESPSNR FEVASGQQTT SPMVGQGGGA
1110 1120 1130 1140 1150
GGQASSNQRG SAVDSKTNEN GETNESNQDA MSTSSDLLDL LLQEDSRSGT
1160 1170 1180 1190 1200
GSAASGSGSS GTGSSGSGSG SSGSGSNGCS SSGSGTRSSQ SSNTSKYFGS
1210 1220 1230 1240 1250
VDSSENSHSR KQTAEGDGEA QFIKCVLQDP IWLLMANTDE KTMMTYQLPI
1260 1270 1280 1290 1300
RDRDSVLKED RAALRAMQKH QPRFTEEQKS ELSQVHPWIR TGRLPRAINI
1310 1320 1330 1340 1350
SACAGCRSPP SVPSATPFDV EIHEMEFCSV LAVAEEKQTP ADTVMEKSET
1360 1370 1380 1390
DGQNETCKEN NGTVTTAQIN DQEMLTEEQE MTSQIEEEMG ASHTQMTH
Length:1,398
Mass (Da):149,649
Last modified:July 22, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i40E6E5E86B2285D0
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
CU672227 Genomic DNA No translation available.
BC163718 mRNA Translation: AAI63718.1

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSDART00000011082; ENSDARP00000007258; ENSDARG00000012499
ENSDART00000182821; ENSDARP00000155485; ENSDARG00000012499

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CU672227 Genomic DNA No translation available.
BC163718 mRNA Translation: AAI63718.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

STRINGi7955.ENSDARP00000007258

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSDART00000011082; ENSDARP00000007258; ENSDARG00000012499
ENSDART00000182821; ENSDARP00000155485; ENSDARG00000012499

Organism-specific databases

ZFINiZDB-GENE-040419-1 per1b

Phylogenomic databases

eggNOGiKOG3753 Eukaryota
ENOG410Y118 LUCA
GeneTreeiENSGT00940000159217
HOGENOMiHOG000231111
OMAiPGERGCH
TreeFamiTF318445

Gene expression databases

BgeeiENSDARG00000012499 Expressed in 16 organ(s), highest expression level in pharyngeal gill

Family and domain databases

CDDicd00130 PAS, 1 hit
InterProiView protein in InterPro
IPR000014 PAS
IPR035965 PAS-like_dom_sf
IPR013655 PAS_fold_3
IPR022728 Period_circadian-like_C
PfamiView protein in Pfam
PF08447 PAS_3, 1 hit
PF12114 Period_C, 1 hit
SMARTiView protein in SMART
SM00091 PAS, 2 hits
SUPFAMiSSF55785 SSF55785, 1 hit
PROSITEiView protein in PROSITE
PS50112 PAS, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB3DK47_DANRE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B3DK47
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: June 5, 2019
This is version 75 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Technical termi

Complete proteome, Reference proteomeImported
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