UniProtKB - B3DJE0 (B3DJE0_DANRE)
Protein
Submitted name:
SRY-box containing gene 5
Gene
sox5
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 558 – 626 | HMG boxPROSITE-ProRule annotationAdd BLAST | 69 |
GO - Molecular functioni
- transcription regulatory region sequence-specific DNA binding Source: GO_Central
GO - Biological processi
- cell fate commitment Source: GO_Central
- negative regulation of transcription, DNA-templated Source: GO_Central
- positive regulation of chondrocyte differentiation Source: GO_Central
- positive regulation of transcription by RNA polymerase II Source: GO_Central
Keywordsi
Molecular function | DNA-bindingPROSITE-ProRule annotation |
Names & Taxonomyi
Protein namesi | Submitted name: SRY-box containing gene 5ImportedSubmitted name: SRY-box transcription factor 5Imported |
Gene namesi | Name:sox5Imported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-000607-13, sox5 |
Subcellular locationi
Nucleus
- nucleus Source: GO_Central
Keywords - Cellular componenti
NucleusPROSITE-ProRule annotationExpressioni
Gene expression databases
Bgeei | ENSDARG00000011582, Expressed in retina and 42 other tissues |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 558 – 626 | HMG boxInterPro annotationAdd BLAST | 69 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 1 – 29 | DisorderedSequence analysisAdd BLAST | 29 | |
Regioni | 53 – 134 | DisorderedSequence analysisAdd BLAST | 82 | |
Regioni | 354 – 436 | DisorderedSequence analysisAdd BLAST | 83 | |
Regioni | 688 – 759 | DisorderedSequence analysisAdd BLAST | 72 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 189 – 209 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 211 – 269 | Sequence analysisAdd BLAST | 59 | |
Coiled coili | 457 – 487 | Sequence analysisAdd BLAST | 31 | |
Coiled coili | 498 – 518 | Sequence analysisAdd BLAST | 21 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 90 – 116 | PolarSequence analysisAdd BLAST | 27 | |
Compositional biasi | 354 – 378 | PolarSequence analysisAdd BLAST | 25 | |
Compositional biasi | 394 – 412 | PolarSequence analysisAdd BLAST | 19 | |
Compositional biasi | 691 – 710 | PolarSequence analysisAdd BLAST | 20 | |
Compositional biasi | 718 – 735 | PolyampholyteSequence analysisAdd BLAST | 18 | |
Compositional biasi | 736 – 750 | AcidicSequence analysisAdd BLAST | 15 |
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
GeneTreei | ENSGT00940000156122 |
TreeFami | TF320471 |
Family and domain databases
Gene3Di | 1.10.30.10, 1 hit |
InterProi | View protein in InterPro IPR009071, HMG_box_dom IPR036910, HMG_box_dom_sf |
Pfami | View protein in Pfam PF00505, HMG_box, 1 hit |
SMARTi | View protein in SMART SM00398, HMG, 1 hit |
SUPFAMi | SSF47095, SSF47095, 1 hit |
PROSITEi | View protein in PROSITE PS50118, HMG_BOX_2, 1 hit |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All
B3DJE0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MLTEPELPQE FNRMSSKRPA SPYGGTDGEV VMATSRQRLE DEEVDGHAVI
60 70 80 90 100
HLPLSSYCSK VSPRSPRLLD SPPTLHANMD QDGSKGLALS PYAQHNSSTS
110 120 130 140 150
PSKQQQEDSS MRPGSEPGSA SALGTPERRK GSLADVVDTL KQRKMEELIK
160 170 180 190 200
NEPEEAPSIE RLLSKDWKDK LLAMGSGNFG EIKGTPDSLA EKERQLMGMI
210 220 230 240 250
TQLSSLREQL LAAHEEQKKL AASQIEKQRQ QMELAKQQQD QIARQQQQLL
260 270 280 290 300
QQQHKINLLQ QQIQQVQGQL PPLMIPVFPP DQRTLAAAAA QQGFLLPPGF
310 320 330 340 350
NYKPGCSEPY PLQLIPTTMA AAAAATPGLG PLQLQQLYAA QLAAMQVSPG
360 370 380 390 400
AKHSTVPQAN LATGTLSPTS GQSEKNRSTP PPKPKDEGAQ PLNLSSKPKA
410 420 430 440 450
SESKSPTSPA SPQVPALKLG PGSLKHSAPS SIGGPPSRLS SIDLLSSITS
460 470 480 490 500
AGYLNDHEAV TKAFQEARKM KEQLKREEQV LDAKVAAVNS LSLNNGRSEK
510 520 530 540 550
EKAALESLSQ QLKQSEESKF THAMMDFGIS GDSDGSPSVS DSRIFREARG
560 570 580 590 600
RGSSEPHIKR PMNAFMVWAK DERRKILQAF PDMHNSNISK ILGSRWKSMT
610 620 630 640 650
NLEKQPYYEE QARLSKQHLE KYPDYKYKPR PKRTCLVDGK KLRIGEYKAI
660 670 680 690 700
MRNRRQEMRQ YFTVGQQAQL PLSSAGVVYP GALSMAGMPS PQMPSEHSSM
710 720 730 740 750
SSSPEPVPPT SQASYFKEVE PRVKEELRMD DGNGDAYDDF DYEDDDGDYG
SDSENHITQ
Computationally mapped potential isoform sequencesi
There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basketQ5RH23 | Q5RH23_DANRE | SRY-box transcription factor 5 | sox5 | 757 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX649261 Genomic DNA No translation available. CR792413 Genomic DNA No translation available. BC163449 mRNA Translation: AAI63449.1 |
Genome annotation databases
Ensembli | ENSDART00000162945; ENSDARP00000137633; ENSDARG00000011582 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX649261 Genomic DNA No translation available. CR792413 Genomic DNA No translation available. BC163449 mRNA Translation: AAI63449.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PaxDbi | B3DJE0 |
Genome annotation databases
Ensembli | ENSDART00000162945; ENSDARP00000137633; ENSDARG00000011582 |
Organism-specific databases
ZFINi | ZDB-GENE-000607-13, sox5 |
Phylogenomic databases
GeneTreei | ENSGT00940000156122 |
TreeFami | TF320471 |
Gene expression databases
Bgeei | ENSDARG00000011582, Expressed in retina and 42 other tissues |
Family and domain databases
Gene3Di | 1.10.30.10, 1 hit |
InterProi | View protein in InterPro IPR009071, HMG_box_dom IPR036910, HMG_box_dom_sf |
Pfami | View protein in Pfam PF00505, HMG_box, 1 hit |
SMARTi | View protein in SMART SM00398, HMG, 1 hit |
SUPFAMi | SSF47095, SSF47095, 1 hit |
PROSITEi | View protein in PROSITE PS50118, HMG_BOX_2, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B3DJE0_DANRE | |
Accessioni | B3DJE0Primary (citable) accession number: B3DJE0 Secondary accession number(s): A0A0R4INR5 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 22, 2008 |
Last sequence update: | July 22, 2008 | |
Last modified: | February 10, 2021 | |
This is version 94 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |