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Protein
Submitted name:

Ntn1b protein

Gene

ntn1b

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

GO - Biological processi

  • anterior commissure morphogenesis Source: ZFIN
  • central nervous system projection neuron axonogenesis Source: ZFIN
  • dendrite development Source: ZFIN
  • olfactory bulb axon guidance Source: ZFIN
  • regulation of axon extension Source: ZFIN

Names & Taxonomyi

Protein namesi
Submitted name:
Ntn1b proteinImported
Gene namesi
Name:ntn1bImported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-990415-168 ntn1b

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

SecretedSAAS annotation

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_500278591021 – 602Sequence analysisAdd BLAST582

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi286 ↔ 303PROSITE-ProRule annotation
Disulfide bondi305 ↔ 314PROSITE-ProRule annotation
Disulfide bondi370 ↔ 379PROSITE-ProRule annotation
Disulfide bondi403 ↔ 415PROSITE-ProRule annotation
Disulfide bondi405 ↔ 422PROSITE-ProRule annotation
Disulfide bondi424 ↔ 433PROSITE-ProRule annotation
Disulfide bondi436 ↔ 450PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bondPROSITE-ProRule annotationSAAS annotation

Structurei

3D structure databases

ProteinModelPortaliB3DJ84
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini46 – 283Laminin N-terminalInterPro annotationAdd BLAST238
Domaini284 – 339Laminin EGF-likeInterPro annotationAdd BLAST56
Domaini340 – 402Laminin EGF-likeInterPro annotationAdd BLAST63
Domaini403 – 452Laminin EGF-likeInterPro annotationAdd BLAST50
Domaini471 – 602NTRInterPro annotationAdd BLAST132

Keywords - Domaini

Laminin EGF-like domainPROSITE-ProRule annotation, SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3512 Eukaryota
ENOG410XS7U LUCA
HOGENOMiHOG000286017
HOVERGENiHBG006464

Family and domain databases

Gene3Di2.60.120.1490, 1 hit
InterProiView protein in InterPro
IPR008979 Galactose-bd-like_sf
IPR002049 Laminin_EGF
IPR008211 Laminin_N
IPR038684 Laminin_N_sf
IPR001134 Netrin_domain
IPR018933 Netrin_module_non-TIMP
IPR008993 TIMP-like_OB-fold
PfamiView protein in Pfam
PF00053 Laminin_EGF, 3 hits
PF00055 Laminin_N, 1 hit
PF01759 NTR, 1 hit
SMARTiView protein in SMART
SM00643 C345C, 1 hit
SM00180 EGF_Lam, 3 hits
SM00136 LamNT, 1 hit
SUPFAMiSSF49785 SSF49785, 1 hit
SSF50242 SSF50242, 1 hit
PROSITEiView protein in PROSITE
PS01248 EGF_LAM_1, 1 hit
PS50027 EGF_LAM_2, 3 hits
PS51117 LAMININ_NTER, 1 hit
PS50189 NTR, 1 hit

Sequencei

Sequence statusi: Complete.

B3DJ84-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MIRILVTCVS MVSITSMVSG ARGGYGMSMF AAQSSPPDPC YDENGNPRRC
60 70 80 90 100
IPDFVNSAFG KDVRVSSTCG SPPSRYCVVT EKGEERSRDC NICDATDPKK
110 120 130 140 150
THPPAYLTDL NNPHNLTCWQ SENYVQYPQN VTLTLSLGKK FEVTYVSLQF
160 170 180 190 200
CSPRPESMAI FKSMDYGKTW VPFQFYSTQC KKMYNKPSKA AITKQNEQEA
210 220 230 240 250
ICTDSHTDMQ PLTGGLIAFS TLDGRPSAHD FDNSPVLQDW VTATDIKVTF
260 270 280 290 300
NRLHTFGDEN EDDSELARDS YFYAVSDLQV GGRCKCNGHA SKCVKDREGN
310 320 330 340 350
LVCECKHNTA GPECDRCKPF HYDRPWQRAT AREANECVAC HCNLHARRCR
360 370 380 390 400
FNMELYKLSG RRSGGVCLNC RHNTAGRHCH YCKEGYYRDM SKAISHRRAC
410 420 430 440 450
KACDCHPVGA AGKTCNQTTG QCPCKDGVTG ITCNRCAKGY QQSRSPIAPC
460 470 480 490 500
IKIPVAAPTS SYSSPDEPTD CDSHCKAPKG KMKVTMKKYC KKDFAVQVHV
510 520 530 540 550
LKGDKAGEWW KFTINIISVY KQGGHRIRRG DQLLWVRAKD VACKCPKIKP
560 570 580 590 600
GRKYLLMGSD EEEDSRGQSG VVADRGSLLI PWKDLWARRL RKFQQRDKRG

KC
Length:602
Mass (Da):67,520
Last modified:July 22, 2008 - v1
Checksum:iE39DCD6668F9B35F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC163393 mRNA Translation: AAI63393.1
UniGeneiDr.75773

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC163393 mRNA Translation: AAI63393.1
UniGeneiDr.75773

3D structure databases

ProteinModelPortaliB3DJ84
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Organism-specific databases

ZFINiZDB-GENE-990415-168 ntn1b

Phylogenomic databases

eggNOGiKOG3512 Eukaryota
ENOG410XS7U LUCA
HOGENOMiHOG000286017
HOVERGENiHBG006464

Family and domain databases

Gene3Di2.60.120.1490, 1 hit
InterProiView protein in InterPro
IPR008979 Galactose-bd-like_sf
IPR002049 Laminin_EGF
IPR008211 Laminin_N
IPR038684 Laminin_N_sf
IPR001134 Netrin_domain
IPR018933 Netrin_module_non-TIMP
IPR008993 TIMP-like_OB-fold
PfamiView protein in Pfam
PF00053 Laminin_EGF, 3 hits
PF00055 Laminin_N, 1 hit
PF01759 NTR, 1 hit
SMARTiView protein in SMART
SM00643 C345C, 1 hit
SM00180 EGF_Lam, 3 hits
SM00136 LamNT, 1 hit
SUPFAMiSSF49785 SSF49785, 1 hit
SSF50242 SSF50242, 1 hit
PROSITEiView protein in PROSITE
PS01248 EGF_LAM_1, 1 hit
PS50027 EGF_LAM_2, 3 hits
PS51117 LAMININ_NTER, 1 hit
PS50189 NTR, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB3DJ84_DANRE
AccessioniPrimary (citable) accession number: B3DJ84
Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: April 25, 2018
This is version 55 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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