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Protein

Protein Wnt

Gene

wnt1

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Ligand for members of the frizzled family of seven transmembrane receptors.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionDevelopmental proteinUniRule annotationSAAS annotation
Biological processWnt signaling pathwayUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Protein WntUniRule annotation
Gene namesi
Name:wnt1Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-980526-526 wnt1

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Extracellular matrixSAAS annotation, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 20Sequence analysisAdd BLAST20
ChainiPRO_501010514021 – 370Protein WntSequence analysisAdd BLAST350

Keywords - PTMi

Disulfide bondSAAS annotation

Expressioni

Gene expression databases

BgeeiENSDARG00000055554
ExpressionAtlasiB3DI55 baseline

Interactioni

GO - Molecular functioni

Structurei

3D structure databases

SMRiB3DI55
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the Wnt family.UniRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiKOG3913 Eukaryota
ENOG410XQZ1 LUCA
HOVERGENiHBG001595
KOiK03209

Family and domain databases

InterProiView protein in InterPro
IPR005817 Wnt
IPR009139 Wnt1
IPR018161 Wnt_CS
PANTHERiPTHR12027 PTHR12027, 2 hits
PfamiView protein in Pfam
PF00110 wnt, 1 hit
PRINTSiPR01841 WNT1PROTEIN
PR01349 WNTPROTEIN
SMARTiView protein in SMART
SM00097 WNT1, 1 hit
PROSITEiView protein in PROSITE
PS00246 WNT1, 1 hit

Sequencei

Sequence statusi: Complete.

B3DI55-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRVLALLLAV KAACVLLVSS LTGTGAVNNS GRWWGIVNVA SSGNLLTNSK
60 70 80 90 100
NVQLVLDPSL ALLSRRQRKL IRQNPGILHA IAAGLHTAIK ECKWQFRNRR
110 120 130 140 150
WNCPTTHSPN VFGKIVNRGC RETAFVFAIT SAGVTHAVAR SCSEGAIESC
160 170 180 190 200
TCDYRRRGPG GPDWHWGGCS DNVEFGRMFG REFVDSSERG RDLRYLTNLH
210 220 230 240 250
NNEAGRMTVA SEMQQECKCH GMSGSCTVRT CWMRLPSFRL VGDYLKDRFD
260 270 280 290 300
GASRVVYANK GSNRASHRAD PRHLEPENPA HKLPSSRDLV YFEKSPNFCS
310 320 330 340 350
YNGKTGTHGT SGRTCNSSSP ALDGCELLCC GRGYKTRMEQ VTERCHCTFH
360 370
WCCHVSCLNC TSTQTVHQCL
Length:370
Mass (Da):41,011
Last modified:July 22, 2008 - v1
Checksum:iF2AB0A82DB031D3E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC163003 mRNA Translation: AAI63003.1
BC163014 mRNA Translation: AAI63014.1
RefSeqiNP_001188327.1, NM_001201398.1
UniGeneiDr.85371

Genome annotation databases

GeneIDi30128
KEGGidre:30128

Similar proteinsi

Entry informationi

Entry nameiB3DI55_DANRE
AccessioniPrimary (citable) accession number: B3DI55
Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: June 20, 2018
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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