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UniProtKB - B3DH72 (B3DH72_DANRE)
Protein
Submitted name:
Opioid receptor, delta 1b
Gene
oprd1b
Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Functioni
GO - Molecular functioni
- G protein-coupled enkephalin receptor activity Source: ZFIN
- G protein-coupled receptor activity Source: GO_Central
- morphine receptor activity Source: ZFIN
- neuropeptide binding Source: GO_Central
- peptide binding Source: GO_Central
GO - Biological processi
- G protein-coupled opioid receptor signaling pathway Source: ZFIN
- neuropeptide signaling pathway Source: GO_Central
Keywordsi
Molecular function | G-protein coupled receptorUniRule annotation, Receptor, Transducer |
Names & Taxonomyi
Protein namesi | Submitted name: Opioid receptor, delta 1bImportedSubmitted name: Oprd1b proteinImported |
Gene namesi | Name:oprd1bImported |
Organismi | Danio rerio (Zebrafish) (Brachydanio rerio)Imported |
Taxonomic identifieri | 7955 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Actinopterygii › Neopterygii › Teleostei › Ostariophysi › Cypriniformes › Danionidae › Danioninae › Danio |
Proteomesi |
|
Organism-specific databases
ZFINi | ZDB-GENE-030131-8473, oprd1b |
Subcellular locationi
Plasma membrane
- Cell membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Other locations
- Membrane ARBA annotation; Multi-pass membrane protein ARBA annotation
Plasma Membrane
- integral component of plasma membrane Source: ZFIN
Other locations
- neuron projection Source: GO_Central
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 50 – 79 | HelicalSequence analysisAdd BLAST | 30 | |
Transmembranei | 91 – 109 | HelicalSequence analysisAdd BLAST | 19 | |
Transmembranei | 129 – 149 | HelicalSequence analysisAdd BLAST | 21 | |
Transmembranei | 170 – 193 | HelicalSequence analysisAdd BLAST | 24 | |
Transmembranei | 213 – 244 | HelicalSequence analysisAdd BLAST | 32 | |
Transmembranei | 265 – 289 | HelicalSequence analysisAdd BLAST | 25 | |
Transmembranei | 301 – 327 | HelicalSequence analysisAdd BLAST | 27 |
Keywords - Cellular componenti
MembraneExpressioni
Gene expression databases
Bgeei | ENSDARG00000037159, Expressed in brain and 27 other tissues |
Structurei
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 71 – 324 | G_PROTEIN_RECEP_F1_2InterPro annotationAdd BLAST | 254 |
Sequence similaritiesi
Belongs to the G-protein coupled receptor 1 family.UniRule annotation
Keywords - Domaini
Transmembrane, Transmembrane helixSequence analysisARBA annotationPhylogenomic databases
eggNOGi | KOG3656, Eukaryota |
GeneTreei | ENSGT00940000157669 |
HOGENOMi | CLU_009579_8_1_1 |
OMAi | RVEQNSF |
OrthoDBi | 1011272at2759 |
TreeFami | TF315737 |
Family and domain databases
InterProi | View protein in InterPro IPR000276, GPCR_Rhodpsn IPR017452, GPCR_Rhodpsn_7TM IPR001418, Opioid_rcpt |
Pfami | View protein in Pfam PF00001, 7tm_1, 1 hit |
PRINTSi | PR00237, GPCRRHODOPSN PR00384, OPIOIDR |
PROSITEi | View protein in PROSITE PS00237, G_PROTEIN_RECEP_F1_1, 1 hit PS50262, G_PROTEIN_RECEP_F1_2, 1 hit |
i Sequence
Sequence statusi: Complete.
B3DH72-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEPPTVTVSD FSERYPLFLH NSSFLEEPAG LLSNWSGGSS ELKAVRGSSA
60 70 80 90 100
VAIAVSITAL YSVICVVGLV GNVLVMYGVV RYTKMKTATN IYIFNLALAD
110 120 130 140 150
ALATSTLPFQ SAKYLMGTWP FGELLCKVVI AIDYYNMFTS IFTLTMMSVD
160 170 180 190 200
RYIAVCHPVR ALDFRTPVKA KIINICVWIL SSAVGFPVMV MAVTKELDSG
210 220 230 240 250
KTICMLKFPD PEWYWDTVTK ICVFIFAFVF PVLVITVCYG LMILRLKSVR
260 270 280 290 300
LLSGSKEKDR NLRRITRMVL VVVAAFIICW TPIHIFIIVK TVVEIDQKNL
310 320 330 340 350
LVVACWHLCI ALGYMNSSLN PVLYAFLDEN FKRCFREFCL PFRTRIEQNS
360 370
FSKARSVIRE PISVCAKSES IKQPT
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CR855299 Genomic DNA No translation available. BC162661 mRNA Translation: AAI62661.1 |
RefSeqi | NP_997920.2, NM_212755.2 |
Genome annotation databases
Ensembli | ENSDART00000054037; ENSDARP00000054036; ENSDARG00000037159 |
GeneIDi | 336529 |
KEGGi | dre:336529 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CR855299 Genomic DNA No translation available. BC162661 mRNA Translation: AAI62661.1 |
RefSeqi | NP_997920.2, NM_212755.2 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 7955.ENSDARP00000054036 |
Chemistry databases
ChEMBLi | CHEMBL4105711 |
Protein family/group databases
GPCRDBi | Search... |
Genome annotation databases
Ensembli | ENSDART00000054037; ENSDARP00000054036; ENSDARG00000037159 |
GeneIDi | 336529 |
KEGGi | dre:336529 |
Organism-specific databases
CTDi | 336529 |
ZFINi | ZDB-GENE-030131-8473, oprd1b |
Phylogenomic databases
eggNOGi | KOG3656, Eukaryota |
GeneTreei | ENSGT00940000157669 |
HOGENOMi | CLU_009579_8_1_1 |
OMAi | RVEQNSF |
OrthoDBi | 1011272at2759 |
TreeFami | TF315737 |
Gene expression databases
Bgeei | ENSDARG00000037159, Expressed in brain and 27 other tissues |
Family and domain databases
InterProi | View protein in InterPro IPR000276, GPCR_Rhodpsn IPR017452, GPCR_Rhodpsn_7TM IPR001418, Opioid_rcpt |
Pfami | View protein in Pfam PF00001, 7tm_1, 1 hit |
PRINTSi | PR00237, GPCRRHODOPSN PR00384, OPIOIDR |
PROSITEi | View protein in PROSITE PS00237, G_PROTEIN_RECEP_F1_1, 1 hit PS50262, G_PROTEIN_RECEP_F1_2, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | B3DH72_DANRE | |
Accessioni | B3DH72Primary (citable) accession number: B3DH72 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 22, 2008 |
Last sequence update: | July 22, 2008 | |
Last modified: | January 19, 2022 | |
This is version 97 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |