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Entry version 57 (10 Feb 2021)
Sequence version 1 (22 Jul 2008)
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Protein
Submitted name:

Prtga protein

Gene

prtga

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at transcript leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Submitted name:
Prtga proteinImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:prtgaImported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri7955 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesDanionidaeDanioninaeDanio

Organism-specific databases

Zebrafish Information Network genome database

More...
ZFINi
ZDB-GENE-061204-4, prtga

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/subcellular%5Flocation%5Fsection">'Subcellular location'</a> section describes the extent of a membrane-spanning region of the protein. It denotes the presence of both alpha-helical transmembrane regions and the membrane spanning regions of beta-barrel transmembrane proteins.<p><a href='/help/transmem' target='_top'>More...</a></p>Transmembranei935 – 955HelicalSequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Cellular componenti

Membrane

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini42 – 117Ig-likeInterPro annotationAdd BLAST76
Domaini122 – 209Ig-likeInterPro annotationAdd BLAST88
Domaini222 – 309Ig-likeInterPro annotationAdd BLAST88
Domaini314 – 399Ig-likeInterPro annotationAdd BLAST86
Domaini408 – 502Fibronectin type-IIIInterPro annotationAdd BLAST95
Domaini504 – 600Fibronectin type-IIIInterPro annotationAdd BLAST97
Domaini605 – 704Fibronectin type-IIIInterPro annotationAdd BLAST100
Domaini711 – 804Fibronectin type-IIIInterPro annotationAdd BLAST94
Domaini809 – 905Fibronectin type-IIIInterPro annotationAdd BLAST97

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni646 – 666DisorderedSequence analysisAdd BLAST21
Regioni1060 – 1149DisorderedSequence analysisAdd BLAST90

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi1060 – 1086PolarSequence analysisAdd BLAST27
Compositional biasi1087 – 1110PolyampholyteSequence analysisAdd BLAST24

Keywords - Domaini

Immunoglobulin domainARBA annotation, RepeatARBA annotation, Transmembrane, Transmembrane helixSequence analysis

Family and domain databases

Conserved Domains Database

More...
CDDi
cd00063, FN3, 5 hits

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.60.40.10, 9 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR013098, Ig_I-set
IPR003599, Ig_sub
IPR003598, Ig_sub2

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00041, fn3, 5 hits
PF07679, I-set, 3 hits

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00060, FN3, 5 hits
SM00409, IG, 4 hits
SM00408, IGc2, 4 hits

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF48726, SSF48726, 4 hits
SSF49265, SSF49265, 3 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50853, FN3, 5 hits
PS50835, IG_LIKE, 4 hits

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B3DH37-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MASFKRDLYL FLAVFLSISG VWSFSELFFI KEPHDVTAMR RDAVVLDCQA
60 70 80 90 100
HGEAPIGIRW LKNGVTITES ERVYSLSNGS LLISEVESRK DKSDEGFYQC
110 120 130 140 150
LAQNKYGSIL SQRARLTIAS LSTFTQQPAS IIVMEGSVAR FTCKITATPP
160 170 180 190 200
PIITWEFNRV TLPLATERIT VLPSGVLQIQ GVEQRDAGSY RCVAANIVSR
210 220 230 240 250
RRSAEATLTV TPAMSPRAPQ RPRIIAGPQN LTVPAHSTAL LECMASGNPR
260 270 280 290 300
PLISWSRADH KSIDVHKTKV LGNGNLIISD VNPQHAGIYF CRATTPGTRN
310 320 330 340 350
YTIAAANITV LAPPSLVEWP ESVTRPRAGT ARFVCTAEGF PTPQITWLKN
360 370 380 390 400
GEPVRSNGRI KMYNSKLVIN QIIPEDDGIY QCEAENIQGS VLAMARLIVV
410 420 430 440 450
MSDNRPSAPR NIRADTVSSS AILLAWDRPA YNSEKVIAYS VHYMKAEGLN
460 470 480 490 500
NEEYQIVIGN DTTRYIIDDL EAGRNYTFYI VAYMPMGASR MSDHVIQHTL
510 520 530 540 550
EDVPLRAPEL SLTSRSPSDI QVSWQPLSHK LSRGRVSAYR LSYRTSSDGT
560 570 580 590 600
LTQLELSAHK THQLLEGLQP DTTYLLRIAA ATAVGWGEPS AWSSHRTPKA
610 620 630 640 650
SSTKVPLAPE LQLESLNCTT VTLRWHLPAG SSSGLQGFKL SYHEEGQPEA
660 670 680 690 700
AQAQIPPHHR QHTIGGLDPR KKYHIKLLAF SFMGDGYQAD QTISTPGCVS
710 720 730 740 750
VRDRLVPPPP PPHHVYAHSN SSSSVFLHWA RPAFTSAQTL NYTVRCNPVG
760 770 780 790 800
LQNASLVLYL QTAAQSLLVT DLEPNTNYEF AVRLHVDLLS SPWSPVVYQT
810 820 830 840 850
TLPEAPSRAP VGVKVTLIEG DSALVSWKAP DDRSAAAVTH YTVLYATRRA
860 870 880 890 900
WAAGDWQMMQ REGSITMALL ENLQPGQVYL VQVSASNQMG DGPFSAAVEL
910 920 930 940 950
TIHTDGHAPR THGSSHSTVF SDGFYHLDQR SMTGIAVGVC IALTCIIICI
960 970 980 990 1000
LILACRSKTR KSCTTKSIRQ AGGQTPPTAV RLANESAAES VEVMMPMMRD
1010 1020 1030 1040 1050
HFIDAKGGTN LIINSYGPVK PTIEKKRRKR WSFFKKNEKE VKKISSPAYS
1060 1070 1080 1090 1100
YHPGTTLLCY TETSPENPPT TLQGLFGPSG GDSEGSHSSE GSHETSDSGR
1110 1120 1130 1140
YSHDDTEATN VSIRSRPASL QDDENQTPVH EKQLETTLQE QEMTDLHPV
Length:1,149
Mass (Da):126,327
Last modified:July 22, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i0A74465665AB8780
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
BC162624 mRNA Translation: AAI62624.1
BC162639 mRNA Translation: AAI62639.1

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC162624 mRNA Translation: AAI62624.1
BC162639 mRNA Translation: AAI62639.1

3D structure databases

Database of comparative protein structure models

More...
ModBasei
Search...

SWISS-MODEL Interactive Workspace

More...
SWISS-MODEL-Workspacei
Submit a new modelling project...

Organism-specific databases

ZFINiZDB-GENE-061204-4, prtga

Family and domain databases

CDDicd00063, FN3, 5 hits
Gene3Di2.60.40.10, 9 hits
InterProiView protein in InterPro
IPR003961, FN3_dom
IPR036116, FN3_sf
IPR007110, Ig-like_dom
IPR036179, Ig-like_dom_sf
IPR013783, Ig-like_fold
IPR013098, Ig_I-set
IPR003599, Ig_sub
IPR003598, Ig_sub2
PfamiView protein in Pfam
PF00041, fn3, 5 hits
PF07679, I-set, 3 hits
SMARTiView protein in SMART
SM00060, FN3, 5 hits
SM00409, IG, 4 hits
SM00408, IGc2, 4 hits
SUPFAMiSSF48726, SSF48726, 4 hits
SSF49265, SSF49265, 3 hits
PROSITEiView protein in PROSITE
PS50853, FN3, 5 hits
PS50835, IG_LIKE, 4 hits

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB3DH37_DANRE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B3DH37
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: February 10, 2021
This is version 57 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)
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