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Protein

Fibroblast growth factor

Gene

fgf2

Organism
Danio rerio (Zebrafish) (Brachydanio rerio)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • fibroblast growth factor receptor signaling pathway Source: InterPro
  • Kupffer's vesicle development Source: ZFIN

Keywordsi

Molecular functionGrowth factorSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Fibroblast growth factorUniRule annotation
Short name:
FGFUniRule annotation
Gene namesi
Name:fgf2Imported
OrganismiDanio rerio (Zebrafish) (Brachydanio rerio)Imported
Taxonomic identifieri7955 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiActinopterygiiNeopterygiiTeleosteiOstariophysiCypriniformesCyprinidaeDanio

Organism-specific databases

ZFINiZDB-GENE-040318-1 fgf2

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Interactioni

GO - Molecular functioni

Family & Domainsi

Sequence similaritiesi

Belongs to the heparin-binding growth factors family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG3885 Eukaryota
ENOG4111IPH LUCA
HOVERGENiHBG007580
KOiK18497

Family and domain databases

CDDicd00058 FGF, 1 hit
InterProiView protein in InterPro
IPR028223 FGF2
IPR002209 Fibroblast_GF_fam
IPR008996 IL1/FGF
PANTHERiPTHR11486 PTHR11486, 1 hit
PTHR11486:SF83 PTHR11486:SF83, 1 hit
PfamiView protein in Pfam
PF00167 FGF, 1 hit
PRINTSiPR00263 HBGFFGF
SMARTiView protein in SMART
SM00442 FGF, 1 hit
SUPFAMiSSF50353 SSF50353, 1 hit
PROSITEiView protein in PROSITE
PS00247 HBGF_FGF, 1 hit

Sequencei

Sequence statusi: Complete.

B3DGE3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MATGGITTLP AAPDAENSSF PAGSFRDPKR LYCKNGGFFL RINADGRVDG
60 70 80 90 100
ARDKSDPHIR LQLQATAVGE VLIKGICTNR FLAMNADGRL FGTKRTTDEC
110 120 130 140 150
YFLERLESNN YNTYRSRKYP DWYVALKRTG QYKSGSKTSP GQKAILFLPM

SAKC
Length:154
Mass (Da):17,114
Last modified:July 22, 2008 - v1
Checksum:i2B28A02B35E1B39B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC162367 mRNA Translation: AAI62367.1
AY269790 mRNA Translation: AAP32155.1
RefSeqiNP_997988.1, NM_212823.2
UniGeneiDr.88830

Genome annotation databases

GeneIDi404231
KEGGidre:404231

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC162367 mRNA Translation: AAI62367.1
AY269790 mRNA Translation: AAP32155.1
RefSeqiNP_997988.1, NM_212823.2
UniGeneiDr.88830

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi404231
KEGGidre:404231

Organism-specific databases

CTDi2247
ZFINiZDB-GENE-040318-1 fgf2

Phylogenomic databases

eggNOGiKOG3885 Eukaryota
ENOG4111IPH LUCA
HOVERGENiHBG007580
KOiK18497

Family and domain databases

CDDicd00058 FGF, 1 hit
InterProiView protein in InterPro
IPR028223 FGF2
IPR002209 Fibroblast_GF_fam
IPR008996 IL1/FGF
PANTHERiPTHR11486 PTHR11486, 1 hit
PTHR11486:SF83 PTHR11486:SF83, 1 hit
PfamiView protein in Pfam
PF00167 FGF, 1 hit
PRINTSiPR00263 HBGFFGF
SMARTiView protein in SMART
SM00442 FGF, 1 hit
SUPFAMiSSF50353 SSF50353, 1 hit
PROSITEiView protein in PROSITE
PS00247 HBGF_FGF, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB3DGE3_DANRE
AccessioniPrimary (citable) accession number: B3DGE3
Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: February 28, 2018
This is version 70 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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