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Entry version 51 (10 Feb 2021)
Sequence version 1 (22 Jul 2008)
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Protein

ULP_PROTEASE domain-containing protein

Gene

OTT_1962

Organism
Orientia tsutsugamushi (strain Ikeda) (Rickettsia tsutsugamushi)
Status
Unreviewed-Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

Enzyme and pathway databases

BioCyc Collection of Pathway/Genome Databases

More...
BioCyci
OTSU334380:G1G2K-2144-MONOMER

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
ULP_PROTEASE domain-containing proteinInterPro annotation
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Ordered Locus Names:OTT_1962Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiOrientia tsutsugamushi (strain Ikeda) (Rickettsia tsutsugamushi)Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri334380 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRickettsialesRickettsiaceaeRickettsieaeOrientia
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000001033 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

SWISS-MODEL Repository - a database of annotated 3D protein structure models

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SMRi
B3CVM3

Database of comparative protein structure models

More...
ModBasei
Search...

Protein Data Bank in Europe - Knowledge Base

More...
PDBe-KBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini1 – 146ULP_PROTEASEInterPro annotationAdd BLAST146

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and domains' section denotes the positions of regions of coiled coil within the protein.<p><a href='/help/coiled' target='_top'>More...</a></p>Coiled coili218 – 238Sequence analysisAdd BLAST21
Coiled coili529 – 549Sequence analysisAdd BLAST21

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_256494_0_0_5

Identification of Orthologs from Complete Genome Data

More...
OMAi
YINEHIA

Database of Orthologous Groups

More...
OrthoDBi
282337at2

Family and domain databases

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR038765, Papain-like_cys_pep_sf
IPR003653, Peptidase_C48_C

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF02902, Peptidase_C48, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF54001, SSF54001, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50600, ULP_PROTEASE, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequencei

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

B3CVM3-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MANDQDLSNP EYLYTEDDIN QLLKHYLGLD DRISIIQHVA LNESLLLKQT
60 70 80 90 100
LHQVLSDIFS GMQEKAVIPL HTGNNHWVAM AIKKGMNDDI VISYNDPMGV
110 120 130 140 150
SIDDKVTLIN CIKELCPGAK INDLQTVQQT NVYDCGPFVV DNLIKMSQGQ
160 170 180 190 200
PILSTEEAKQ QAQNIRQSQV NFLSENRMIT SAAAALADTL LKNNNRITEG
210 220 230 240 250
VLVDRIFDNK ILSVQEKQQL LNNLLDNHIK ENKSLTKESL TRMLASTHFV
260 270 280 290 300
QQQANVLLNE KFNKSTANLQ ASNASAEVSS KEELYVPKIN QVEESLEAQL
310 320 330 340 350
KYINEHIASQ LMQIVKNSNG EIDCNSSNFQ EEVSSLLNSR SKETTSLATI
360 370 380 390 400
EQNFNEIIQQ LRKEKVNEER VSAIELQLKA NRAVLEAKLS NTEDVKSLVN
410 420 430 440 450
QKIKEETLQA IPFFGNAAER ANFKKHLAHF VKLPDNSYSL LKQKEKRHPF
460 470 480 490 500
CNIIGANAVK FFSPQSNAVY LNTSAYNQIT SGNLKAFEAA VTTDINNLML
510 520 530 540 550
KEAAVTIDAV SPNKEAVESG KDLSKTDELA ELKEVKSNLE TELKILKERL
560 570 580 590 600
VKKVTSNLET ELKFFKGRLV QELMQIVKNE NGRIDHTSKN WQESASVLLN
610 620 630 640 650
SQEKGAVSLA EVERAVSKMT QKLRDQKVSE EEVVNIESKL KFERASLEAK
660 670 680 690 700
LFDDNEIKEL INKRIKEDAL RAIPFLGSDS ESFMEKISPF VKLPDDSYSL
710 720 730 740 750
LKANDKHHPF QNILYSNALK FFADSSDIGY LNDDSLKNLT PENLNAFEQA
760 770 780 790 800
VAADIDKLMS RDVTLNVSDL KSYVANSPNP DLIADYLALE WQIHTPGLKG
810 820 830 840 850
LYDDLQASHQ LQLNELENKH AKQLLSDLAN LSKLPSMRGI LPEFKDEFYN
860 870 880 890 900
EIDKKPEERS VEYKNFINKC SELPDAMLQP AKCSAQALLE FNKYERDLNS
910 920 930 940 950
FKQGVFCAID NYKNSGTAQS KRDFDRAEIL YKGPDGVVKE ITLQELQESQ
960 970 980 990 1000
DLALSNEQKE FLVTSWQQGN FRSGSTAIYG GSKFSSNSTG MIFDGGGRCD
1010 1020 1030 1040 1050
ILIDASNGTK VHSRYFSTFA ESQNIDEKRV PCFDSTISVD ISNMTGDKFI
1060 1070 1080 1090 1100
PGCSSAPQIL INMHKFDPAV SVLDIPEGLK ITRSYAREEI DNVKKDFVSG
1110 1120 1130 1140 1150
ALNMICSQYA EKDISTQLSQ ETLDTKFDRG WRNITETLGL DNALDSIIKE
1160 1170 1180 1190 1200
VYSQNSDNKS LKTEPDIQSR ANEVIMEDIL DIVKRARSGV DSSSLHESQS
1210 1220 1230 1240 1250
LTLQKAVDRF CKVEVDPILR EKFAGKCLDT FFSEQHGNIY DKDVQKAVEE
1260 1270 1280 1290 1300
EVTSILSPLC NEKEKGTLKK NTSAMVKKLV SKYNNKKGWH GAWESFKNTV
1310 1320 1330 1340 1350
SNVVGYLTGQ NRKVEKLISS HPEITRSLKR HLSDSALSEC RASSESISEN
1360
LSTAITSKAR SNSTGNIR
Length:1,368
Mass (Da):153,611
Last modified:July 22, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i84702DF9EB311D1C
GO

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AP008981 Genomic DNA Translation: BAG41420.1

NCBI Reference Sequences

More...
RefSeqi
WP_012462337.1, NC_010793.1

Genome annotation databases

Ensembl bacterial and archaeal genome annotation project

More...
EnsemblBacteriai
BAG41420; BAG41420; OTT_1962

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
ott:OTT_1962

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AP008981 Genomic DNA Translation: BAG41420.1
RefSeqiWP_012462337.1, NC_010793.1

3D structure databases

Select the link destinations:

Protein Data Bank Europe

More...
PDBei

Protein Data Bank RCSB

More...
RCSB PDBi

Protein Data Bank Japan

More...
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
6UPSX-ray2.00A1-259[»]
6UPUX-ray2.20A/E/I/M1-259[»]
SMRiB3CVM3
ModBaseiSearch...
PDBe-KBiSearch...

Genome annotation databases

EnsemblBacteriaiBAG41420; BAG41420; OTT_1962
KEGGiott:OTT_1962

Phylogenomic databases

HOGENOMiCLU_256494_0_0_5
OMAiYINEHIA
OrthoDBi282337at2

Enzyme and pathway databases

BioCyciOTSU334380:G1G2K-2144-MONOMER

Family and domain databases

InterProiView protein in InterPro
IPR038765, Papain-like_cys_pep_sf
IPR003653, Peptidase_C48_C
PfamiView protein in Pfam
PF02902, Peptidase_C48, 1 hit
SUPFAMiSSF54001, SSF54001, 1 hit
PROSITEiView protein in PROSITE
PS50600, ULP_PROTEASE, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

More...
ProtoNeti
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiB3CVM3_ORITI
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B3CVM3
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/TrEMBL: July 22, 2008
Last sequence update: July 22, 2008
Last modified: February 10, 2021
This is version 51 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiUnreviewed (UniProtKB/TrEMBL)

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources
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