UniProtKB - B3CLG2 (ATPL_WOLPP)
ATP synthase subunit c
atpE
Functioni
F1F0 ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F1 containing the extramembraneous catalytic core and F0 containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation.
UniRule annotationKey component of the F0 channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F1 delta and epsilon subunits.
UniRule annotationSites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sitei | 58 | Reversibly protonated during proton transportUniRule annotation | 1 |
GO - Molecular functioni
- lipid binding Source: UniProtKB-KW
- proton-transporting ATP synthase activity, rotational mechanism Source: UniProtKB-UniRule
Keywordsi
Biological process | ATP synthesis, Hydrogen ion transport, Ion transport, Transport |
Ligand | Lipid-binding |
Names & Taxonomyi
Protein namesi | Recommended name: ATP synthase subunit cUniRule annotationAlternative name(s): ATP synthase F(0) sector subunit cUniRule annotation F-type ATPase subunit cUniRule annotation Short name: F-ATPase subunit cUniRule annotation Lipid-binding proteinUniRule annotation |
Gene namesi | Name:atpEUniRule annotation Ordered Locus Names:WP0622 |
Organismi | Wolbachia pipientis subsp. Culex pipiens (strain wPip) |
Taxonomic identifieri | 570417 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Alphaproteobacteria › Rickettsiales › Anaplasmataceae › Wolbachieae › Wolbachia › unclassified Wolbachia › |
Proteomesi |
|
Subcellular locationi
Plasma membrane
- Cell membrane UniRule annotation; Multi-pass membrane protein UniRule annotation
Plasma Membrane
- plasma membrane Source: UniProtKB-SubCell
Other locations
- integral component of membrane Source: UniProtKB-KW
- proton-transporting ATP synthase complex, coupling factor F(o) Source: UniProtKB-KW
Topology
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Transmembranei | 8 – 28 | HelicalUniRule annotationAdd BLAST | 21 | |
Transmembranei | 52 – 72 | HelicalUniRule annotationAdd BLAST | 21 |
Keywords - Cellular componenti
Cell membrane, CF(0), MembranePTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_1000184535 | 1 – 75 | ATP synthase subunit cAdd BLAST | 75 |
Interactioni
Subunit structurei
F-type ATPases have 2 components, F1 - the catalytic core - and F0 - the membrane proton channel. F1 has five subunits: alpha3, beta3, gamma1, delta1, epsilon1. F0 has three main subunits: a1, b2 and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F1 is attached to F0 by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.
UniRule annotationProtein-protein interaction databases
STRINGi | 570417.WP0622 |
Family & Domainsi
Sequence similaritiesi
Keywords - Domaini
Transmembrane, Transmembrane helixPhylogenomic databases
eggNOGi | COG0636, Bacteria |
HOGENOMi | CLU_148047_4_0_5 |
OMAi | MDPQAAK |
OrthoDBi | 2078221at2 |
Family and domain databases
Gene3Di | 1.20.20.10, 1 hit |
HAMAPi | MF_01396, ATP_synth_c_bact, 1 hit |
InterProi | View protein in InterPro IPR005953, ATP_synth_csu_bac/chlpt IPR000454, ATP_synth_F0_csu IPR020537, ATP_synth_F0_csu_DDCD_BS IPR038662, ATP_synth_F0_csu_sf IPR002379, ATPase_proteolipid_c-like_dom IPR035921, F/V-ATP_Csub_sf |
PANTHERi | PTHR10031, PTHR10031, 1 hit |
Pfami | View protein in Pfam PF00137, ATP-synt_C, 1 hit |
PRINTSi | PR00124, ATPASEC |
SUPFAMi | SSF81333, SSF81333, 1 hit |
TIGRFAMsi | TIGR01260, ATP_synt_c, 1 hit |
PROSITEi | View protein in PROSITE PS00605, ATPASE_C, 1 hit |
i Sequence
Sequence statusi: Complete.
10 20 30 40 50
MDLVALKFIA IGLAVFGMLG AGLGIANIFS AMLNGIARNP ESEGKMKSYV
60 70
YIGAAMVEIM GLLAFVLAML LIFAA
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AM999887 Genomic DNA Translation: CAQ54730.1 |
RefSeqi | WP_006014985.1, NC_010981.1 |
Genome annotation databases
EnsemblBacteriai | CAQ54730; CAQ54730; WP0622 |
GeneIDi | 61803032 |
KEGGi | wpi:WP0622 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AM999887 Genomic DNA Translation: CAQ54730.1 |
RefSeqi | WP_006014985.1, NC_010981.1 |
3D structure databases
SMRi | B3CLG2 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 570417.WP0622 |
Genome annotation databases
EnsemblBacteriai | CAQ54730; CAQ54730; WP0622 |
GeneIDi | 61803032 |
KEGGi | wpi:WP0622 |
Phylogenomic databases
eggNOGi | COG0636, Bacteria |
HOGENOMi | CLU_148047_4_0_5 |
OMAi | MDPQAAK |
OrthoDBi | 2078221at2 |
Family and domain databases
Gene3Di | 1.20.20.10, 1 hit |
HAMAPi | MF_01396, ATP_synth_c_bact, 1 hit |
InterProi | View protein in InterPro IPR005953, ATP_synth_csu_bac/chlpt IPR000454, ATP_synth_F0_csu IPR020537, ATP_synth_F0_csu_DDCD_BS IPR038662, ATP_synth_F0_csu_sf IPR002379, ATPase_proteolipid_c-like_dom IPR035921, F/V-ATP_Csub_sf |
PANTHERi | PTHR10031, PTHR10031, 1 hit |
Pfami | View protein in Pfam PF00137, ATP-synt_C, 1 hit |
PRINTSi | PR00124, ATPASEC |
SUPFAMi | SSF81333, SSF81333, 1 hit |
TIGRFAMsi | TIGR01260, ATP_synt_c, 1 hit |
PROSITEi | View protein in PROSITE PS00605, ATPASE_C, 1 hit |
MobiDBi | Search... |
Entry informationi
Entry namei | ATPL_WOLPP | |
Accessioni | B3CLG2Primary (citable) accession number: B3CLG2 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 28, 2009 |
Last sequence update: | July 22, 2008 | |
Last modified: | September 29, 2021 | |
This is version 81 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |