Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
1 to 0 of 0  Show
  1. 1
    "Erroneous class switching and false VDJ recombination: Molecular dissection of t(8;14)/MYC-IGH translocations in Burkitt-type lymphoblastic leukemia/B-cell lymphoma."
    Burmeister T., Molkentin M., Schwartz S., Gokbuget N., Hoelzer D., Thiel E., Reinhardt R.
    Mol. Oncol. 7:850-858(2013) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Category: Sequences.
    Source: UniProtKB/TrEMBL (unreviewed).

    This publication is cited by 49 other entries.

  2. 2
    "c-myc gene mutation in gastric mucosa-associated lymphoid tissue (MALT) lymphoma and diffuse large B-cell lymphoma."
    Hiyama T., Haruma K., Kitadai Y., Ito M., Masuda H., Miyamoto M., Tanaka S., Yoshihara M., Sumii K., Shimamoto F., Chayama K.
    Oncol Rep 8:289-292(2001) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Observational study of gene-disease association. (HuGE Navigator).
    Source: GeneRIF:4609.

    This publication is mapped to 60 other entries.

  3. 3
    Category: Function.
    Annotation: Review: EBV regulates c-MYC apoptosis and tumorigenicity in Burkitt's lymphoma.
    Source: GeneRIF:4609.

    This publication is mapped to 60 other entries.

  4. 4
    "A Myc-associated zinc finger protein-related factor binding site is required for the deregulation of c-myc expression by the immunoglobulin heavy chain gene enhancers in Burkitt's lymphoma."
    Hu H.M., Arcinas M., Boxer L.M.
    J Biol Chem 277:9819-9824(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: We have located a region in the c-myc promoter that is required for the complete activation by the immunoglobulin heavy chain gene enhancer.
    Source: GeneRIF:4609.

    This publication is mapped to 60 other entries.

  5. 5
    "Expression of the proto-oncogene c-myc in human stenotic aortocoronary bypass grafts."
    Hilker M., Tellmann G., Buerke M., Moersig W., Oelert H., Lehr H.A., Hake U.
    Pathol Res Pract 197:811-816(2001) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Expression.
    Annotation: In Situ studies demonstrate enhanced mRNA expression of the proto-oncogene c-myc in stenotic venous bypass grafts.
    Source: GeneRIF:4609.

    This publication is mapped to 60 other entries.

  6. 6
    "Direct interaction of c-Myc with Smad2 and Smad3 to inhibit TGF-beta-mediated induction of the CDK inhibitor p15(Ink4B)."
    Feng X.H., Liang Y.Y., Liang M., Zhai W., Lin X.
    Mol Cell 9:133-143(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: c-Myc physically interacts with Smad2 and Smad3 involved in TGF-beta signaling.c-Myc promotes cell growth and cancer development partly by inhibiting the growth inhibitory functions of Smads.
    Source: GeneRIF:4609.

    This publication is mapped to 60 other entries.

  7. 7
    "Uteroglobin promoter-targeted c-MYC expression in transgenic mice cause hyperplasia of Clara cells and malignant transformation of T-lymphoblasts and tubular epithelial cells."
    Geick A., Redecker P., Ehrhardt A., Klocke R., Paul D., Halter R.
    Transgenic Res 10:501-511(2001) [PubMed] [Europe PMC] [Abstract]
    Category: Expression, Sequences.
    Annotation: Uteroglobin promoter-targeted c-MYC expression in transgenic mice cause hyperplasia of Clara cells and malignant transformation of T-lymphoblasts and tubular epithelial cells.
    Source: GeneRIF:4609.

    This publication is mapped to 69 other entries.

  8. 8
    "c-Myc initiates illegitimate replication of the ribonucleotide reductase R2 gene."
    Kuschak T.I., Kuschak B.C., Taylor C.L., Wright J.A., Wiener F., Mai S.
    Oncogene 21:909-920(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: initiates illegitimate recombination of ribonucleotide reductase 2 gene.
    Source: GeneRIF:4609.

    This publication is mapped to 62 other entries.

  9. 9
    "Acute hyperglycaemia induces changes in the transcription levels of 4 major genes in human endothelial cells: macroarrays-based expression analysis."
    Chettab K., Zibara K., Belaiba S.R., McGregor J.L.
    Thromb Haemost 87:141-148(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Expression, Sequences.
    Annotation: Acute hyperglycaemia induces an up-regulation of seven major genes four of which were not previously reported in the literature. Northern blot analyses performed on these 4 genes confirm macroarrays results for alphav beta4 c-myc and MUC18.
    Source: GeneRIF:4609.

    This publication is mapped to 79 other entries.

  10. 10
    "Activation of c-MYC and c-MYB proto-oncogenes is associated with decreased apoptosis in tumor colon progression."
    Greco C., Alvino S., Buglioni S., Assisi D., Lapenta R., Grassi A., Stigliano V., Mottolese M., Casale V.
    Anticancer Res 21:3185-3192(2001) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Activation of c-MYC and c-MYB proto-oncogenes is associated with decreased apoptosis in tumor colon progression.
    Source: GeneRIF:4609.

    This publication is mapped to 73 other entries.

  11. 11
    "A new case of acute nonlymphocytic leukemia (French-American-British subtype M1) with double minutes and c-MYC amplification."
    Rodon N., Sole F., Espinet B., Salido M., Zamora L., Cigudosa J.C., Woessner S., Florensa L.
    Cancer Genet Cytogenet 132:161-164(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: amplification in acute nonlymphocytic leukemia.
    Source: GeneRIF:4609.

    This publication is mapped to 60 other entries.

  12. 12
    "Repression of alpha-fetoprotein gene expression under hypoxic conditions in human hepatoma cells: characterization of a negative hypoxia response element that mediates opposite effects of hypoxia inducible factor-1 and c-Myc."
    Mazure N.M., Chauvet C., Bois-Joyeux B., Bernard M.A., Nacer-Cherif H., Danan J.L.
    Cancer Res 62:1158-1165(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: Repression of alpha-fetoprotein gene expression under hypoxic conditions in human hepatoma cells: characterization of a negative hypoxia response element that mediates opposite effects of hypoxia inducible factor-1 and c-Myc.
    Source: GeneRIF:4609.

    This publication is mapped to 72 other entries.

  13. 13
    "Regulation of c-myc expression in leukemic cell line Meg-01 by the death domain of Fas gene."
    Liu H., Shan J., Tang S., Liu S.
    Zhonghua Xue Ye Xue Za Zhi 22:9-12(2001) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: The cytoplasmic domain of gp130 is involve the induction of c-myc expression and the cell proliferation in Meg-01 cell.
    Source: GeneRIF:4609.

    This publication is mapped to 71 other entries.

  14. 14
    "Retinoic acid-induced cell cycle arrest of human myeloid cell lines is associated with sequential down-regulation of c-Myc and cyclin E and posttranscriptional up-regulation of p27(Kip1)."
    Dimberg A., Bahram F., Karlberg I., Larsson L.G., Nilsson K., Oberg F.
    Blood 99:2199-2206(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Retinoic acid-induced cell cycle arrest of human myeloid cell lines is associated with sequential down-regulation of c-Myc and cyclin E.
    Source: GeneRIF:4609.

    This publication is mapped to 74 other entries.

  15. 15
    "Scatter factor/hepatocyte growth factor stimulation of glioblastoma cell cycle progression through G(1) is c-Myc dependent and independent of p27 suppression, Cdk2 activation, or E2F1-dependent transcription."
    Walter K.A., Hossain M.A., Luddy C., Goel N., Reznik T.E., Laterra J.
    Mol Cell Biol 22:2703-2715(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: Scatter factor/hepatocyte growth factor stimulation of glioblastoma cell cycle progression through G(1) is c-Myc dependent and independent of p27 suppression Cdk2 activation or E2F1-dependent transcription.
    Source: GeneRIF:4609.

    This publication is mapped to 65 other entries.

  16. 16
    "A novel tricomplex of BRCA1, Nmi, and c-Myc inhibits c-Myc-induced human telomerase reverse transcriptase gene (hTERT) promoter activity in breast cancer."
    Li H., Lee T.H., Avraham H.
    J Biol Chem 277:20965-20973(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: complex with Nmi and BRCA1 inhibits c-Myc-induced human telomerase reverse transcriptase gene promoter activity in breast cancer.
    Source: GeneRIF:4609.

    This publication is mapped to 64 other entries.

  17. 17
    "c-myc-induced apoptosis in polycystic kidney disease is independent of FasL/Fas interaction."
    Couillard M., Guillaume R., Tanji N., D'Agati V., Trudel M.
    Cancer Res 62:2210-2214(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Interaction.
    Annotation: c-myc-induced apoptosis in polycystic kidney disease is independent of FasL/Fas interaction.
    Source: GeneRIF:4609.

    This publication is mapped to 71 other entries.

  18. 18
    "The N-myc and c-myc downstream pathways include the chromosome 17q genes nm23-H1 and nm23-H2."
    Godfried M.B., Veenstra M., v Sluis P., Boon K., v Asperen R., Hermus M.C., v Schaik B.D., Voute T.P., Schwab M., Versteeg R., Caron H.N.
    Oncogene 21:2097-2101(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: The N-myc and c-myc downstream pathways include the chromosome 17q genes nm23-H1 and nm23-H2.
    Source: GeneRIF:4609.

    This publication is mapped to 65 other entries.

  19. 19
    "Estrogen and Myc negatively regulate expression of the EphA2 tyrosine kinase."
    Zelinski D.P., Zantek N.D., Walker-Daniels J., Peters M.A., Taparowsky E.J., Kinch M.S.
    J Cell Biochem 85:714-720(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function, Interaction.
    Annotation: estrogen and Myc negatively regulate EphA2 expression in mammary epithelial cells.
    Source: GeneRIF:4609.

    This publication is mapped to 65 other entries.

  20. 20
    "A novel form of the RelA nuclear factor kappaB subunit is induced by and forms a complex with the proto-oncogene c-Myc."
    Chapman N.R., Webster G.A., Gillespie P.J., Wilson B.J., Crouch D.H., Perkins N.D.
    Biochem J 366:459-469(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Interaction.
    Annotation: A novel form of the RelA nuclear factor kappaB subunit is induced by and forms a complex with this proto-oncogene protein.
    Source: GeneRIF:4609.

    This publication is mapped to 69 other entries.

  21. 21
    "Overexpression of translocation-associated fusion genes of FGFRI, MYC, NPMI, and DEK, but absence of the translocations in acute myeloid leukemia. A microarray analysis."
    Larramendy M.L., Niini T., Elonen E., Nagy B., Ollila J., Vihinen M., Knuutila S.
    Haematologica 87:569-577(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Expression.
    Annotation: overexpressed in acute myeloid leukemia while translocations associated with this gene are absent.
    Source: GeneRIF:4609.

    This publication is mapped to 97 other entries.

  22. 22
    "The proto-oncogene c-myc in hematopoietic development and leukemogenesis."
    Hoffman B., Amanullah A., Shafarenko M., Liebermann D.A.
    Oncogene 21:3414-3421(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: The proto-oncogene c-myc in hematopoietic development and leukemogenesis.
    Source: GeneRIF:4609.

    This publication is mapped to 60 other entries.

  23. 23
    "c-Myc can induce DNA damage, increase reactive oxygen species, and mitigate p53 function: a mechanism for oncogene-induced genetic instability."
    Vafa O., Wade M., Kern S., Beeche M., Pandita T.K., Hampton G.M., Wahl G.M.
    Mol Cell 9:1031-1044(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: c-Myc can induce DNA damage increase reactive oxygen species and mitigate p53 function.
    Source: GeneRIF:4609.

    This publication is mapped to 244 other entries.

  24. 24
    "Newly established clear cell sarcoma (malignant melanoma of soft parts) cell line expressing melanoma-associated Melan-A antigen and overexpressing C-MYC oncogene."
    Moritake H., Sugimoto T., Asada Y., Yoshida M.A., Maehara Y., Epstein A.L., Kuroda H.
    Cancer Genet Cytogenet 135:48-56(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Sequences.
    Annotation: Overexpression of c-myc mRNA was found in an Achilles tendon clear cell sarcoma and may have a role in its malignant progression.
    Source: GeneRIF:4609.

    This publication is mapped to 62 other entries.

  25. 25
    "TRRAP-dependent and TRRAP-independent transcriptional activation by Myc family oncoproteins."
    Nikiforov M.A., Chandriani S., Park J., Kotenko I., Matheos D., Johnsson A., McMahon S.B., Cole M.D.
    Mol Cell Biol 22:5054-5063(2002) [PubMed] [Europe PMC] [Abstract]
    Category: Function.
    Annotation: TRRAP binding and the recruitment of histone H3 and H4 acetyltransferase activities are required for the transactivation of a silent TERT gene in exponentially growing human fibroblasts by c-Myc or N-Myc protein.
    Source: GeneRIF:4609.

    This publication is mapped to 63 other entries.

1 to 0 of 0  Show
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

We'd like to inform you that we have updated our Privacy Notice to comply with Europe’s new General Data Protection Regulation (GDPR) that applies since 25 May 2018.

Do not show this banner again