UniProtKB - B2ZPG7 (B2ZPG7_FORTA)
Protein
Eukaryotic translation initiation factor 3 subunit I
Gene
N/A
Organism
Forcipomyia taiwana (Bloodsucking midge) (Lasiohelea taiwana)
Status
Functioni
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.UniRule annotation
GO - Molecular functioni
- translation initiation factor activity Source: UniProtKB-UniRule
GO - Biological processi
- formation of cytoplasmic translation initiation complex Source: UniProtKB-UniRule
Keywordsi
Molecular function | Initiation factorUniRule annotationImportedARBA annotation |
Biological process | Protein biosynthesis |
Names & Taxonomyi
Protein namesi | Recommended name: Eukaryotic translation initiation factor 3 subunit IUniRule annotationShort name: eIF3iUniRule annotation |
Organismi | Forcipomyia taiwana (Bloodsucking midge) (Lasiohelea taiwana)Imported |
Taxonomic identifieri | 515531 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Ecdysozoa › Arthropoda › Hexapoda › Insecta › Pterygota › Neoptera › Holometabola › Diptera › Nematocera › Chironomoidea › Ceratopogonidae › Forcipomyiinae › Forcipomyia › Lasiohelea |
Subcellular locationi
Other locations
- Cytoplasm UniRule annotation
Other locations
- eukaryotic 43S preinitiation complex Source: UniProtKB-UniRule
- eukaryotic 48S preinitiation complex Source: UniProtKB-UniRule
- eukaryotic translation initiation factor 3 complex Source: UniProtKB-UniRule
Keywords - Cellular componenti
CytoplasmUniRule annotationInteractioni
Subunit structurei
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex.
UniRule annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 6 – 226 | WD_REPEATS_REGIONInterPro annotationAdd BLAST | 221 | |
Repeati | 6 – 37 | WDPROSITE-ProRule annotationAdd BLAST | 32 | |
Repeati | 48 – 89 | WDPROSITE-ProRule annotationAdd BLAST | 42 | |
Repeati | 143 – 184 | WDPROSITE-ProRule annotationAdd BLAST | 42 | |
Repeati | 185 – 226 | WDPROSITE-ProRule annotationAdd BLAST | 42 | |
Domaini | 282 – 325 | WD_REPEATS_REGIONInterPro annotationAdd BLAST | 44 | |
Repeati | 282 – 312 | WDPROSITE-ProRule annotationAdd BLAST | 31 |
Sequence similaritiesi
Belongs to the eIF-3 subunit I family.UniRule annotation
Keywords - Domaini
RepeatARBA annotation, WD repeatPROSITE-ProRule annotationARBA annotationFamily and domain databases
Gene3Di | 2.130.10.10, 1 hit |
HAMAPi | MF_03008, eIF3i, 1 hit |
InterProi | View protein in InterPro IPR027525, eIF3i IPR015943, WD40/YVTN_repeat-like_dom_sf IPR001680, WD40_repeat IPR019775, WD40_repeat_CS IPR017986, WD40_repeat_dom IPR036322, WD40_repeat_dom_sf |
Pfami | View protein in Pfam PF00400, WD40, 4 hits |
SMARTi | View protein in SMART SM00320, WD40, 6 hits |
SUPFAMi | SSF50978, SSF50978, 1 hit |
PROSITEi | View protein in PROSITE PS00678, WD_REPEATS_1, 2 hits PS50082, WD_REPEATS_2, 5 hits PS50294, WD_REPEATS_REGION, 2 hits |
i Sequence
Sequence statusi: Complete.
B2ZPG7-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MKPLMMQGHE RAITQIKYNR EGDLLFSCAK DHKPNVWFSL NGERLGTFNG
60 70 80 90 100
HAGAVWCVDV DWTTTKLITG SGDMSVRLWD VETGTSVACI PCKSSARTVG
110 120 130 140 150
FSFSGNQAAY STDRAMGHIC ELFVIDSREP DSSLNDGDAI LKIPISQSKI
160 170 180 190 200
TAMIWGTLDE TIITGHENGQ ITLWDLRIGR EINSVNDHMG AINDLQLSKD
210 220 230 240 250
GTMFVSSSRD TTAKLFDSDS LMCLKTYKTE RPVNSAAISP LLEHVVLGGG
260 270 280 290 300
QDAMEVTTTS ARQGKFDSRF FHLIYEEEFA RVKGHFGPIN SLAFHPDGRS
310 320
YATGGEDGFV RLQTFDSSYY EYIFD
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | EU678971 mRNA Translation: ACD65081.1 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | EU678971 mRNA Translation: ACD65081.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein family/group databases
Allergomei | 5775, For t 2 5776, For t 2.0101 |
Family and domain databases
Gene3Di | 2.130.10.10, 1 hit |
HAMAPi | MF_03008, eIF3i, 1 hit |
InterProi | View protein in InterPro IPR027525, eIF3i IPR015943, WD40/YVTN_repeat-like_dom_sf IPR001680, WD40_repeat IPR019775, WD40_repeat_CS IPR017986, WD40_repeat_dom IPR036322, WD40_repeat_dom_sf |
Pfami | View protein in Pfam PF00400, WD40, 4 hits |
SMARTi | View protein in SMART SM00320, WD40, 6 hits |
SUPFAMi | SSF50978, SSF50978, 1 hit |
PROSITEi | View protein in PROSITE PS00678, WD_REPEATS_1, 2 hits PS50082, WD_REPEATS_2, 5 hits PS50294, WD_REPEATS_REGION, 2 hits |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B2ZPG7_FORTA | |
Accessioni | B2ZPG7Primary (citable) accession number: B2ZPG7 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 1, 2008 |
Last sequence update: | July 1, 2008 | |
Last modified: | August 12, 2020 | |
This is version 56 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |