UniProtKB - B2VG76 (NUDC_ERWT9)
Protein
NADH pyrophosphatase
Gene
nudC
Organism
Erwinia tasmaniensis (strain DSM 17950 / CIP 109463 / Et1/99)
Status
Functioni
Catalytic activityi
Cofactori
Protein has several cofactor binding sites:- Mg2+UniRule annotation, Mn2+UniRule annotationNote: Divalent metal cations. Mg2+ or Mn2+.UniRule annotation
- Zn2+UniRule annotationNote: Binds 1 zinc ion per subunit.UniRule annotation
Sites
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Metal bindingi | 98 | ZincUniRule annotation | 1 | |
Metal bindingi | 101 | ZincUniRule annotation | 1 | |
Metal bindingi | 116 | ZincUniRule annotation | 1 | |
Metal bindingi | 119 | ZincUniRule annotation | 1 | |
Metal bindingi | 174 | Divalent metal cationUniRule annotation | 1 | |
Metal bindingi | 178 | Divalent metal cationUniRule annotation | 1 |
GO - Molecular functioni
- magnesium ion binding Source: UniProtKB-UniRule
- manganese ion binding Source: UniProtKB-UniRule
- NAD+ diphosphatase activity Source: UniProtKB-UniRule
- zinc ion binding Source: UniProtKB-UniRule
Keywordsi
Molecular function | Hydrolase |
Ligand | Magnesium, Manganese, Metal-binding, NAD, Zinc |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:nudCUniRule annotation Ordered Locus Names:ETA_01730 |
Organismi | Erwinia tasmaniensis (strain DSM 17950 / CIP 109463 / Et1/99) |
Taxonomic identifieri | 465817 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Gammaproteobacteria › Enterobacterales › Erwiniaceae › Erwinia › |
Proteomesi |
|
PTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_1000115243 | 1 – 261 | NADH pyrophosphataseAdd BLAST | 261 |
Interactioni
Subunit structurei
Homodimer.
UniRule annotationProtein-protein interaction databases
STRINGi | 465817.ETA_01730 |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 125 – 248 | Nudix hydrolaseUniRule annotationAdd BLAST | 124 |
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 159 – 180 | Nudix boxAdd BLAST | 22 |
Sequence similaritiesi
Phylogenomic databases
eggNOGi | ENOG4105E09 Bacteria COG2816 LUCA |
HOGENOMi | HOG000247937 |
KOi | K03426 |
OMAi | FHAEYAG |
OrthoDBi | 1435118at2 |
Family and domain databases
HAMAPi | MF_00297 Nudix_NudC, 1 hit |
InterProi | View protein in InterPro IPR022925 NADH_pyroPase_NudC IPR015797 NUDIX_hydrolase-like_dom_sf IPR000086 NUDIX_hydrolase_dom IPR015376 Znr_NADH_PPase |
Pfami | View protein in Pfam PF00293 NUDIX, 1 hit PF09297 zf-NADH-PPase, 1 hit |
SUPFAMi | SSF55811 SSF55811, 2 hits |
PROSITEi | View protein in PROSITE PS51462 NUDIX, 1 hit |
i Sequence
Sequence statusi: Complete.
B2VG76-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MEREIVSIDA GWWVVSEEHK IWLPAGELPH GDAASLGLAG SSGSRIGEWQ
60 70 80 90 100
GEAVWLIRGS RPDDMGSLRQ LLDRDSALFR LAGRGIQLAE FFRSHQWCGY
110 120 130 140 150
CGHKMHNSRT EWACLCHHCR QRYYPQIAPC IIVAIRRGAE ILLAQHTRHR
160 170 180 190 200
NGIYTVLAGF VEVGETLEQT VAREVMEESS IKVKNLRYVT SQPWPFPQSL
210 220 230 240 250
MVAFMADYDD GEISIDRKEL IDAGWYRYDA LPLLPPAGTV ARRLIEDTVA
260
LCRAQEENGE R
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU468135 Genomic DNA Translation: CAO95219.1 |
RefSeqi | WP_012439940.1, NC_010694.1 |
Genome annotation databases
EnsemblBacteriai | CAO95219; CAO95219; ETA_01730 |
KEGGi | eta:ETA_01730 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CU468135 Genomic DNA Translation: CAO95219.1 |
RefSeqi | WP_012439940.1, NC_010694.1 |
3D structure databases
SMRi | B2VG76 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 465817.ETA_01730 |
Genome annotation databases
EnsemblBacteriai | CAO95219; CAO95219; ETA_01730 |
KEGGi | eta:ETA_01730 |
Phylogenomic databases
eggNOGi | ENOG4105E09 Bacteria COG2816 LUCA |
HOGENOMi | HOG000247937 |
KOi | K03426 |
OMAi | FHAEYAG |
OrthoDBi | 1435118at2 |
Family and domain databases
HAMAPi | MF_00297 Nudix_NudC, 1 hit |
InterProi | View protein in InterPro IPR022925 NADH_pyroPase_NudC IPR015797 NUDIX_hydrolase-like_dom_sf IPR000086 NUDIX_hydrolase_dom IPR015376 Znr_NADH_PPase |
Pfami | View protein in Pfam PF00293 NUDIX, 1 hit PF09297 zf-NADH-PPase, 1 hit |
SUPFAMi | SSF55811 SSF55811, 2 hits |
PROSITEi | View protein in PROSITE PS51462 NUDIX, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | NUDC_ERWT9 | |
Accessioni | B2VG76Primary (citable) accession number: B2VG76 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | March 24, 2009 |
Last sequence update: | July 1, 2008 | |
Last modified: | May 8, 2019 | |
This is version 64 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Complete proteome, Reference proteomeDocuments
- SIMILARITY comments
Index of protein domains and families