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UniProtKB - B2RYE6 (B2RYE6_RAT)
Protein
Submitted name:
GRB10-interacting GYF protein 2
Gene
Gigyf2
Organism
Rattus norvegicus (Rat)
Status
Functioni
GO - Molecular functioni
- proline-rich region binding Source: RGD
GO - Biological processi
- adult locomotory behavior Source: RGD
- cellular protein metabolic process Source: RGD
- feeding behavior Source: RGD
- homeostasis of number of cells within a tissue Source: RGD
- insulin-like growth factor receptor signaling pathway Source: RGD
- mitotic G1 DNA damage checkpoint signaling Source: RGD
- mRNA destabilization Source: RGD
- multicellular organism growth Source: RGD
- musculoskeletal movement Source: RGD
- negative regulation of translation Source: RGD
- neuromuscular process controlling balance Source: RGD
- post-embryonic development Source: RGD
- posttranscriptional gene silencing Source: RGD
- spinal cord motor neuron differentiation Source: RGD
Names & Taxonomyi
Protein namesi | Submitted name: GRB10-interacting GYF protein 2Imported |
Gene namesi | Name:Gigyf2Imported |
Organismi | Rattus norvegicus (Rat)Imported |
Taxonomic identifieri | 10116 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Rattus |
Proteomesi |
|
Organism-specific databases
RGDi | 2318130, Gigyf2 |
Subcellular locationi
Cytosol
- cytosol Source: GO_Central
Endoplasmic reticulum
- endoplasmic reticulum Source: RGD
Endosome
- endosome Source: RGD
Golgi apparatus
- Golgi apparatus Source: RGD
Other locations
- cytoplasm Source: RGD
- cytoplasmic stress granule Source: RGD
- integral component of membrane Source: RGD
- membrane Source: GO_Central
- perikaryon Source: RGD
- protein-containing complex Source: RGD
- proximal dendrite Source: RGD
- vesicle Source: RGD
Expressioni
Gene expression databases
Bgeei | ENSRNOG00000023577, Expressed in testis and 21 other tissues |
Interactioni
GO - Molecular functioni
- proline-rich region binding Source: RGD
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000063708 |
Structurei
Family & Domainsi
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 112 – 132 | DisorderedSequence analysisAdd BLAST | 21 | |
Regioni | 148 – 185 | DisorderedSequence analysisAdd BLAST | 38 |
Phylogenomic databases
eggNOGi | KOG1862, Eukaryota |
GeneTreei | ENSGT00940000156108 |
HOGENOMi | CLU_1460877_0_0_1 |
(1+)i Sequence
Sequence statusi: Complete.
This entry has 1 described isoform and 2 potential isoforms that are computationally mapped.Show allAlign All
B2RYE6-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MAAETQTLNF GPEWLRALSS GGSITSPPLS PALPKYKLAD YRYGREEMLA
60 70 80 90 100
LFLKDYKIPF DLLEKEFLPI LQEEPLPPLA LVPFTEEEQR NFSMSVNSAA
110 120 130 140 150
VLRLTGRGGG GGTVVGAPRG RSSSRGRGRG RGECGFYQRS FDEVEGVFGR
160 170 180
GGGREMHRSQ SWEERGDRRF EKPGRKDVER RRTQL
Computationally mapped potential isoform sequencesi
There are 2 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basketA0A096MKC0 | A0A096MKC0_RAT | GRB10-interacting GYF protein 2 | Gigyf2 | 740 | Annotation score: | ||
A0A096MJI4 | A0A096MJI4_RAT | GRB10-interacting GYF protein 2 | Gigyf2 | 538 | Annotation score: |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07068270 Genomic DNA No translation available. AABR07068271 Genomic DNA No translation available. AABR07068272 Genomic DNA No translation available. BC166750 mRNA Translation: AAI66750.1 |
Genome annotation databases
Ensembli | ENSRNOT00000064965; ENSRNOP00000063708; ENSRNOG00000023577 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AABR07068270 Genomic DNA No translation available. AABR07068271 Genomic DNA No translation available. AABR07068272 Genomic DNA No translation available. BC166750 mRNA Translation: AAI66750.1 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Protein-protein interaction databases
STRINGi | 10116.ENSRNOP00000063708 |
Genome annotation databases
Ensembli | ENSRNOT00000064965; ENSRNOP00000063708; ENSRNOG00000023577 |
Organism-specific databases
RGDi | 2318130, Gigyf2 |
Phylogenomic databases
eggNOGi | KOG1862, Eukaryota |
GeneTreei | ENSGT00940000156108 |
HOGENOMi | CLU_1460877_0_0_1 |
Gene expression databases
Bgeei | ENSRNOG00000023577, Expressed in testis and 21 other tissues |
Family and domain databases
MobiDBi | Search... |
Entry informationi
Entry namei | B2RYE6_RAT | |
Accessioni | B2RYE6Primary (citable) accession number: B2RYE6 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 1, 2008 |
Last sequence update: | July 1, 2008 | |
Last modified: | January 19, 2022 | |
This is version 77 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |