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Protein
Submitted name:

Interleukin-1 receptor-associated kinase 3

Gene

Irak3

Organism
Rattus norvegicus (Rat)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseImported, ReceptorImported, Transferase

Enzyme and pathway databases

ReactomeiR-RNO-9020702 Interleukin-1 signaling

Names & Taxonomyi

Protein namesi
Submitted name:
Interleukin-1 receptor-associated kinase 3Imported
Submitted name:
Interleukin-1 receptor-associated kinase 3 (Predicted)Imported
Gene namesi
Name:Irak3Imported
Synonyms:Irak3_predictedImported
ORF Names:rCG_49175Imported
OrganismiRattus norvegicus (Rat)Imported
Taxonomic identifieri10116 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeRattus
Proteomesi
  • UP000002494 Componenti: Chromosome 7

Organism-specific databases

RGDi1308846 Irak3

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Expressioni

Gene expression databases

BgeeiENSRNOG00000004226

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10116.ENSRNOP00000005686

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini41 – 106DeathInterPro annotationAdd BLAST66
Domaini179 – 464Protein kinaseInterPro annotationAdd BLAST286

Phylogenomic databases

eggNOGiKOG1187 Eukaryota
COG0515 LUCA
GeneTreeiENSGT00530000063073
HOGENOMiHOG000060319
HOVERGENiHBG052146
KOiK04732
OMAiYMPEEYI
OrthoDBiEOG091G0YKT
TreeFamiTF328924

Family and domain databases

InterProiView protein in InterPro
IPR011029 DEATH-like_dom_sf
IPR000488 Death_domain
IPR033610 IRAK3
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
PANTHERiPTHR24419:SF7 PTHR24419:SF7, 1 hit
PfamiView protein in Pfam
PF00531 Death, 1 hit
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00005 DEATH, 1 hit
SUPFAMiSSF47986 SSF47986, 1 hit
SSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS50017 DEATH_DOMAIN, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit

Sequencei

Sequence statusi: Complete.

B2RYC8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAGPCGARGT LSPHSLLFDL PPALLGELCT ILDSCDGPLG WRGLAERLSN
60 70 80 90 100
SWLDVRHIEK YVHQGKSGTR ELLWSWAQKN KTIGDLLQVL HEMGHQRAIH
110 120 130 140 150
LIMNYGVNWT PPVQTHHELR FPNLPPNSKP VCRESDPGPL ELANVTVDNV
160 170 180 190 200
LVPEHNERGV VLHKTPISFQ SILEGTKHFH KDFLIGEGEI FEVYRVEIRN
210 220 230 240 250
QTYAVKLFKQ EKTMQLKKHW KRFLSELEVL LLFNHPHILE LAAYFTEMEK
260 270 280 290 300
LCLVYPYMSN GTLFDRLQCT NGTTPLSWHV RISVLIGIAK AIQCLHNTRP
310 320 330 340 350
CAVICGNISS ANILLDDQFQ PKLTDFAAAH FRPHLEQQSS TINMTGSGRK
360 370 380 390 400
HLWYMPEEYI RQGRLTIKTD VYSFGIVIME VLTGCKVVLD DPKHVQLRDL
410 420 430 440 450
LMELVEKRGL DSCLSFLDRK IPPCPRNFSA KLFSLAGQCV ATRAKLRPTM
460 470 480 490 500
DEVLNTLEST QPSLYFAEDP PTSLKSFRCP SPLFLDNVPS IPVEDDENQN
510 520 530 540 550
NYPVPPKEAL RTDRVTQKTP FECSQSEVTF LGLDRNKGNR GSEAACNMPS
560 570 580 590 600
SSCEECWCPE LAEASQDLRP TVISLGSSWE VPGYSYGSKP MEKRCSSGLF
610
CSEHEQSKRQ
Length:610
Mass (Da):68,977
Last modified:July 1, 2008 - v1
Checksum:i109536C8B35DC3B5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AABR07057296 Genomic DNA No translation available.
AABR07057297 Genomic DNA No translation available.
BC166731 mRNA Translation: AAI66731.1
CH473960 Genomic DNA Translation: EDM16573.1
RefSeqiNP_001101571.1, NM_001108101.1
UniGeneiRn.126158
Rn.147737

Genome annotation databases

EnsembliENSRNOT00000005686; ENSRNOP00000005686; ENSRNOG00000004226
GeneIDi314870
KEGGirno:314870

Similar proteinsi

Entry informationi

Entry nameiB2RYC8_RAT
AccessioniPrimary (citable) accession number: B2RYC8
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: July 18, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

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