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Protein
Submitted name:

3222402P14Rik protein

Gene

Ppp2r3a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Calcium bindingi984 – 995PROSITE-ProRule annotationAdd BLAST12

GO - Molecular functioni

  • calcium ion binding Source: InterPro
  • protein binding, bridging Source: MGI
  • protein phosphatase regulator activity Source: GO_Central

GO - Biological processi

Keywordsi

LigandCalciumPROSITE-ProRule annotation

Names & Taxonomyi

Protein namesi
Submitted name:
3222402P14Rik proteinImported
Submitted name:
MCG15724, isoform CRA_bImported
Submitted name:
Protein phosphatase 2, regulatory subunit B'', alphaImported
Gene namesi
Name:Ppp2r3aImported
Synonyms:3222402P14RikImported
ORF Names:mCG_15724Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 9

Organism-specific databases

MGIiMGI:2442104 Ppp2r3a

Subcellular locationi

Expressioni

Gene expression databases

BgeeiENSMUSG00000043154 Expressed in 238 organ(s), highest expression level in quadriceps femoris

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000075327

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini765 – 792EF-handInterPro annotationAdd BLAST28
Domaini971 – 1006EF-handInterPro annotationAdd BLAST36

Phylogenomic databases

eggNOGiKOG2562 Eukaryota
ENOG410XRBK LUCA
GeneTreeiENSGT00530000063265
HOGENOMiHOG000013216
HOVERGENiHBG000013
KOiK11583
OrthoDBiEOG091G03UQ
TreeFamiTF105554

Family and domain databases

InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
PfamiView protein in Pfam
PF13499 EF-hand_7, 1 hit
SUPFAMiSSF47473 SSF47473, 2 hits
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 1 hit
PS50222 EF_HAND_2, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

B2RXC8-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MAATYRLVVS TVNHYSSVVI DRRFEQAIHY CTGTCHTFTH GIDCIVVHHS
60 70 80 90 100
VCADLVHIPV SQFKDVDLNS VFLSHENGLS SAEDYPHQAL TGLPRGKKAS
110 120 130 140 150
TFQNTCNLKD IAGEAISFAS GKIKEFSLEK LRNSNHAAYR KGRKVKSDSF
160 170 180 190 200
NRRSVDFDLL CGHYNNDGTS PPFGLLRSSS VEEKSLSHRN SLDTNLTSML
210 220 230 240 250
FQNLSEEDLV TQILEKHKID HFSSGTDIKM CLDILLKCSE DLKKCTDIIK
260 270 280 290 300
QCIKKKSGGS ISEGSGNEVI SNSETVYMNV MTRLAYYLRK LPFEFMQSGN
310 320 330 340 350
NETVDLTELI NNIPNLQLTP FSPLYGTEQP PKYEDIVHLS ALDSGQFQTV
360 370 380 390 400
ELQDDKHNFK QTDIVKTTPN NTDSLCSLEV NDPGTLKPVQ LQSPLLTINH
410 420 430 440 450
LENVSSGNLM ETLYIEEESD GKKSLLDKEQ KAENGQGQEP LQVNEHKEFS
460 470 480 490 500
DHDTYLKKCP VSMQNEIGKI FEKPIMVHPS KEDSKLEVPT TDLRDQRHFV
510 520 530 540 550
NPNSQEEIDK LLMDLESFSQ KMETSLGEPL AKGKSINSLN SHSHLTAQSH
560 570 580 590 600
KDLEPKPIAS SAMEKVSPSC LTRIIENNGH KMEEEDRALL LRIMESIEDF
610 620 630 640 650
AQELVECKSG RGSLSQEKEM MQILQETLTT SSQPTPSVCR SPVGEKPKDS
660 670 680 690 700
TSVVLIQQTP EVIKIQNKPE KKPATSFPPA ATLPSSPQPA SPVPCVSDVV
710 720 730 740 750
NTPLSINIPQ FYFPEGLPDT CSNHEQILSR IETAFKDIED QKADIHEMGR
760 770 780 790 800
IAKVCGCPLY WKAPMFRAAG GEKTGFVTAQ SFIAMWKKLL SNRHDDAAKF
810 820 830 840 850
IWLLAKPSCS YLEQEDFIPL LQDVVDTHPG LTFLKDAPEF HSRYITTVVQ
860 870 880 890 900
RIFYTVNRSW SGKITSTEIR KSNFLQTLAL LEEEEDINQI TDYFSYEHFY
910 920 930 940 950
VIYCKFWELD GDHDLYISQA DLSRYNDQAS SNRIIERIFS GAVTRGKTVQ
960 970 980 990 1000
KEGRMSYADF VWFLISEEDK RNPTSIEYWF RCMDVDGDGI LSMYELEYFY
1010 1020 1030 1040 1050
EEQCERMEAM GIEPLPFHDL LCQMLDLVKP ASDGRITLRD LKRCRMAHIF
1060 1070 1080 1090 1100
YDTFFNLEKY LDHEQRDPFA VQKDVENDGP EPSDWDRFAA EEYEALVTEE
1110 1120 1130 1140 1150
SAQVQLQEGS FEDYESDEPV SPSELGNKGN KIVTSSLSEK CGKLQSVDEE
Length:1,150
Mass (Da):130,257
Last modified:July 1, 2008 - v1
Checksum:i44BCE5CE2B4330BF
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
G3X9E8G3X9E8_MOUSE
MCG15724, isoform CRA_a
Ppp2r3a mCG_15724
530Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC120390 Genomic DNA No translation available.
AC138288 Genomic DNA No translation available.
AC242670 Genomic DNA No translation available.
BC151170 mRNA Translation: AAI51171.1
BC151171 mRNA Translation: AAI51172.1
CH466560 Genomic DNA Translation: EDL21039.1
RefSeqiNP_001154834.1, NM_001161362.3
XP_017168836.1, XM_017313347.1
UniGeneiMm.335386

Genome annotation databases

EnsembliENSMUST00000075941; ENSMUSP00000075327; ENSMUSG00000043154
GeneIDi235542
KEGGimmu:235542
UCSCiuc009rfh.3 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC120390 Genomic DNA No translation available.
AC138288 Genomic DNA No translation available.
AC242670 Genomic DNA No translation available.
BC151170 mRNA Translation: AAI51171.1
BC151171 mRNA Translation: AAI51172.1
CH466560 Genomic DNA Translation: EDL21039.1
RefSeqiNP_001154834.1, NM_001161362.3
XP_017168836.1, XM_017313347.1
UniGeneiMm.335386

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000075327

Protocols and materials databases

DNASUi235542
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000075941; ENSMUSP00000075327; ENSMUSG00000043154
GeneIDi235542
KEGGimmu:235542
UCSCiuc009rfh.3 mouse

Organism-specific databases

CTDi5523
MGIiMGI:2442104 Ppp2r3a

Phylogenomic databases

eggNOGiKOG2562 Eukaryota
ENOG410XRBK LUCA
GeneTreeiENSGT00530000063265
HOGENOMiHOG000013216
HOVERGENiHBG000013
KOiK11583
OrthoDBiEOG091G03UQ
TreeFamiTF105554

Miscellaneous databases

ChiTaRSiPpp2r3a mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000043154 Expressed in 238 organ(s), highest expression level in quadriceps femoris

Family and domain databases

InterProiView protein in InterPro
IPR011992 EF-hand-dom_pair
IPR018247 EF_Hand_1_Ca_BS
IPR002048 EF_hand_dom
PfamiView protein in Pfam
PF13499 EF-hand_7, 1 hit
SUPFAMiSSF47473 SSF47473, 2 hits
PROSITEiView protein in PROSITE
PS00018 EF_HAND_1, 1 hit
PS50222 EF_HAND_2, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiB2RXC8_MOUSE
AccessioniPrimary (citable) accession number: B2RXC8
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: November 7, 2018
This is version 84 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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