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Protein
Submitted name:

Cytochrome P450, family 26, subfamily c, polypeptide 1

Gene

Cyp26c1

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • anterior/posterior pattern specification Source: MGI
  • central nervous system development Source: MGI
  • neural crest cell development Source: MGI
  • organelle fusion Source: MGI
  • oxidation-reduction process Source: MGI
  • retinoic acid catabolic process Source: MGI
  • sterol metabolic process Source: GO_Central

Keywordsi

Molecular functionMonooxygenaseUniRule annotation, Oxidoreductase
LigandHemeUniRule annotation, Iron, Metal-binding

Enzyme and pathway databases

ReactomeiR-MMU-211916 Vitamins
R-MMU-5365859 RA biosynthesis pathway

Names & Taxonomyi

Protein namesi
Submitted name:
Cytochrome P450, family 26, subfamily c, polypeptide 1Imported
Gene namesi
Name:Cyp26c1Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:2679699 Cyp26c1

Expressioni

Gene expression databases

BgeeiENSMUSG00000062432 Expressed in 32 organ(s), highest expression level in embryo

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000073105

Family & Domainsi

Sequence similaritiesi

Belongs to the cytochrome P450 family.UniRule annotation

Phylogenomic databases

eggNOGiKOG0157 Eukaryota
COG2124 LUCA
GeneTreeiENSGT00800000124060
HOGENOMiHOG000220829
HOVERGENiHBG051099
KOiK12665
OMAiRYVDCVV
OrthoDBiEOG091G0K6Z
TreeFamiTF105093

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR002401 Cyt_P450_E_grp-I
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
PR00385 P450
SUPFAMiSSF48264 SSF48264, 1 hit
PROSITEiView protein in PROSITE
PS00086 CYTOCHROME_P450, 1 hit

Sequencei

Sequence statusi: Complete.

B2RXA7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MISWGLSCLS VLGAAGTTLL CAGLLLGLAQ QLWTLRWTLS RDWASTLPLP
60 70 80 90 100
KGSMGWPFFG ETLHWLVQGS RFHSSRRERY GTVFKTHLLG RPVIRVSGAE
110 120 130 140 150
NVRTILLGEH RLVRSQWPQS AHILLGSHTL LGAVGEPHRQ RRKVLARVFS
160 170 180 190 200
RSSLEQFVPR LQGALRREVR SWCAAQRPVA VYQAAKALTF RMAARILLGL
210 220 230 240 250
QLDEARCTEL AHTFEQLVEN LFSLPLDVPF SGLRKGIRAR DQLYEHLDEA
260 270 280 290 300
VAEKLQEKQT AEPGDALLLI INSARELGHE PSVQELKELA VELLFAAFFT
310 320 330 340 350
TASASTSLIL LLLQHPAAIT KIQQELSAQG LGRACTCTPR ASGSPPDCGC
360 370 380 390 400
EPDLSLAMLG RLRYVDCVVK EVLRLLPPVS GGYRTALRTF ELDGYQIPKG
410 420 430 440 450
WSVMYSIRDT HETAAVYRSP PEGFDPERFG VESGDARGSG GRFHYIPFGG
460 470 480 490 500
GARSCLGQEL AQAVLQLLAV ELVRTARWEL ATPAFPVMQT VPIVHPVDGL
510
LLFFHPLPTS GAGDGLPF
Length:518
Mass (Da):57,026
Last modified:July 1, 2008 - v1
Checksum:i0A78D11F556AF618
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC110212 Genomic DNA No translation available.
BC151098 mRNA Translation: AAI51099.1
BC151106 mRNA Translation: AAI51107.1
RefSeqiNP_001098671.1, NM_001105201.1
XP_017173748.1, XM_017318259.1
UniGeneiMm.457750

Genome annotation databases

EnsembliENSMUST00000073391; ENSMUSP00000073105; ENSMUSG00000062432
GeneIDi546726
KEGGimmu:546726
UCSCiuc012ble.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC110212 Genomic DNA No translation available.
BC151098 mRNA Translation: AAI51099.1
BC151106 mRNA Translation: AAI51107.1
RefSeqiNP_001098671.1, NM_001105201.1
XP_017173748.1, XM_017318259.1
UniGeneiMm.457750

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000073105

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000073391; ENSMUSP00000073105; ENSMUSG00000062432
GeneIDi546726
KEGGimmu:546726
UCSCiuc012ble.1 mouse

Organism-specific databases

CTDi340665
MGIiMGI:2679699 Cyp26c1

Phylogenomic databases

eggNOGiKOG0157 Eukaryota
COG2124 LUCA
GeneTreeiENSGT00800000124060
HOGENOMiHOG000220829
HOVERGENiHBG051099
KOiK12665
OMAiRYVDCVV
OrthoDBiEOG091G0K6Z
TreeFamiTF105093

Enzyme and pathway databases

ReactomeiR-MMU-211916 Vitamins
R-MMU-5365859 RA biosynthesis pathway

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000062432 Expressed in 32 organ(s), highest expression level in embryo

Family and domain databases

Gene3Di1.10.630.10, 1 hit
InterProiView protein in InterPro
IPR001128 Cyt_P450
IPR017972 Cyt_P450_CS
IPR002401 Cyt_P450_E_grp-I
IPR036396 Cyt_P450_sf
PfamiView protein in Pfam
PF00067 p450, 1 hit
PRINTSiPR00463 EP450I
PR00385 P450
SUPFAMiSSF48264 SSF48264, 1 hit
PROSITEiView protein in PROSITE
PS00086 CYTOCHROME_P450, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB2RXA7_MOUSE
AccessioniPrimary (citable) accession number: B2RXA7
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: November 7, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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