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Protein

Histone H2A

Gene

Hist1h2ad

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionDNA-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Histone H2AUniRule annotation
Gene namesi
Name:Hist1h2adImported
ORF Names:mCG_1044806Imported, mCG_122950Imported, mCG_49394Imported, mCG_49890Imported, mCG_49891Imported, mCG_49925Imported, mCG_50406Imported, mCG_50828Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Chromosome, Nucleosome coreUniRule annotationSAAS annotation, NucleusUniRule annotationSAAS annotation

PTM / Processingi

Proteomic databases

TopDownProteomicsiB2RVF0

Expressioni

Gene expression databases

BgeeiENSMUSG00000061615

Interactioni

Subunit structurei

The nucleosome is a histone octamer containing two molecules each of H2A, H2B, H3 and H4 assembled in one H3-H4 heterotetramer and two H2A-H2B heterodimers. The octamer wraps approximately 147 bp of DNA.UniRule annotationSAAS annotation

GO - Molecular functioni

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini5 – 89HistoneInterPro annotationAdd BLAST85
Domaini92 – 126Histone_H2A_CInterPro annotationAdd BLAST35

Sequence similaritiesi

Belongs to the histone H2A family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG1756 Eukaryota
COG5262 LUCA
HOVERGENiHBG009342
KOiK11251
OMAiPRVSCRA
OrthoDBiEOG091G0XGD

Family and domain databases

CDDicd00074 H2A, 1 hit
Gene3Di1.10.20.10, 1 hit
InterProiView protein in InterPro
IPR009072 Histone-fold
IPR002119 Histone_H2A
IPR007125 Histone_H2A/H2B/H3
IPR032454 Histone_H2A_C
IPR032458 Histone_H2A_CS
PfamiView protein in Pfam
PF00125 Histone, 1 hit
PF16211 Histone_H2A_C, 1 hit
PRINTSiPR00620 HISTONEH2A
SMARTiView protein in SMART
SM00414 H2A, 1 hit
SUPFAMiSSF47113 SSF47113, 1 hit
PROSITEiView protein in PROSITE
PS00046 HISTONE_H2A, 1 hit

Sequencei

Sequence statusi: Complete.

B2RVF0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSGRGKQGGK ARAKAKTRSS RAGLQFPVGR VHRLLRKGNY SERVGAGAPV
60 70 80 90 100
YLAAVLEYLT AEILELAGNA ARDNKKTRII PRHLQLAIRN DEELNKLLGR
110 120 130
VTIAQGGVLP NIQAVLLPKK TESHHKAKGK
Length:130
Mass (Da):14,135
Last modified:July 1, 2008 - v1
Checksum:i9CFE6184B2CC89F5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC147161 mRNA Translation: AAI47162.1
BC147162 mRNA Translation: AAI47163.1
CH466561 Genomic DNA Translation: EDL32539.1
CH466561 Genomic DNA Translation: EDL32548.1
CH466561 Genomic DNA Translation: EDL32553.1
CH466561 Genomic DNA Translation: EDL32555.1
CH466561 Genomic DNA Translation: EDL32607.1
CH466561 Genomic DNA Translation: EDL32623.1
CH466561 Genomic DNA Translation: EDL32628.1
CH466561 Genomic DNA Translation: EDL32635.1
RefSeqiNP_001171015.1, NM_001177544.2
NP_783591.2, NM_175660.3
NP_835489.1, NM_178182.2
NP_835491.1, NM_178184.2
NP_835492.1, NM_178185.2
NP_835493.1, NM_178186.3
NP_835494.1, NM_178187.4
NP_835495.1, NM_178188.4
NP_835496.1, NM_178189.5
UniGeneiMm.14767
Mm.250564
Mm.261665
Mm.261973
Mm.263165
Mm.377876
Mm.390553
Mm.422826
Mm.423402

Genome annotation databases

GeneIDi319164
319165
319166
319167
319170
319171
319172
319191
665433
KEGGimmu:319164
mmu:319165
mmu:319166
mmu:319167
mmu:319170
mmu:319171
mmu:319172
mmu:319191
mmu:665433

Similar proteinsi

Entry informationi

Entry nameiB2RVF0_MOUSE
AccessioniPrimary (citable) accession number: B2RVF0
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: March 28, 2018
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

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