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Protein
Submitted name:

Transient receptor potential cation channel, subfamily M, member 3

Gene

Trpm3

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionReceptorImported

Enzyme and pathway databases

ReactomeiR-MMU-3295583 TRP channels

Names & Taxonomyi

Protein namesi
Submitted name:
Transient receptor potential cation channel, subfamily M, member 3Imported
Gene namesi
Name:Trpm3Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 19

Organism-specific databases

MGIiMGI:2443101 Trpm3

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei885 – 904HelicalSequence analysisAdd BLAST20
Transmembranei952 – 970HelicalSequence analysisAdd BLAST19
Transmembranei982 – 1000HelicalSequence analysisAdd BLAST19
Transmembranei1021 – 1041HelicalSequence analysisAdd BLAST21
Transmembranei1099 – 1124HelicalSequence analysisAdd BLAST26

Keywords - Cellular componenti

Membrane

Expressioni

Gene expression databases

BgeeiENSMUSG00000052387 Expressed in 88 organ(s), highest expression level in pigmented layer of retina

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini891 – 1133Ion_transInterPro annotationAdd BLAST243
Domaini1227 – 1282TRPM_tetraInterPro annotationAdd BLAST56

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili1230 – 1250Sequence analysisAdd BLAST21
Coiled coili1268 – 1288Sequence analysisAdd BLAST21

Keywords - Domaini

Coiled coilSequence analysis, Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiKOG3614 Eukaryota
ENOG410XR5B LUCA
GeneTreeiENSGT00760000119127
HOGENOMiHOG000230920
HOVERGENiHBG055663

Family and domain databases

Gene3Di1.20.5.1010, 1 hit
InterProiView protein in InterPro
IPR005821 Ion_trans_dom
IPR029583 TRPM3
IPR032415 TRPM_tetra
IPR037162 TRPM_tetra_sf
PANTHERiPTHR13800:SF7 PTHR13800:SF7, 1 hit
PfamiView protein in Pfam
PF00520 Ion_trans, 1 hit
PF16519 TRPM_tetra, 1 hit

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 5 potential isoforms that are computationally mapped.Show allAlign All

B2RUS0-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MPGPWGTVYF LGTAQICSFL SSRWNLEGVM NQTDASRPLN WTIRKLCHAA
60 70 80 90 100
FLPSVRLLKA QKSWIERAFY KRECVHIIPS TKDPHRCCCG RLIGQHVGLT
110 120 130 140 150
PSISVLQNEK NESRLSRNDI QSEKWSISKH TQLSPTDAFG TIEFQGGGHS
160 170 180 190 200
NKAMYVRVSF DTKPDLLLHL MTKEWQLELP KLLISVHGGL QNFELQPKLK
210 220 230 240 250
QVFGKGLIKA AMTTGAWIFT GGVNTGVIRH VGDALKDHAS KSRGKICTIG
260 270 280 290 300
IAPWGIVENQ EDLIGRDVVR PYQTMSNPMS KLTVLNSMHS HFILADNGTT
310 320 330 340 350
GKYGAEVKLR RQLEKHISLQ KINTRIGQGV PVVALIVEGG PNVISIVLEY
360 370 380 390 400
LRDTPPVPVV VCDGSGRASD ILAFGHKYSE EGGLINESLR DQLLVTIQKT
410 420 430 440 450
FTYTRTQAQH LFIILMECMK KKELITVFRM GSEGHQDIDL AILTALLKGA
460 470 480 490 500
NASAPDQLSL ALAWNRVDIA RSQIFIYGQQ WPVGSLEQAM LDALVLDRVD
510 520 530 540 550
FVKLLIENGV SMHRFLTISR LEELYNTRHG PSNTLYHLVR DVKKREYPGF
560 570 580 590 600
GWIYFKGNLP PDYRISLIDI GLVIEYLMGG AYRCNYTRKR FRTLYHNLFG
610 620 630 640 650
PKRPKALKLL GMEDDIPLRR GRKTTKKREE EVDIDLDDPE INHFPFPFHE
660 670 680 690 700
LMVWAVLMKR QKMALFFWQH GEEAMAKALV ACKLCKAMAH EASENDMVDD
710 720 730 740 750
ISQELNHNSR DFGQLAVELL DQSYKQDEQL AMKLLTYELK NWSNATCLQL
760 770 780 790 800
AVAAKHRDFI AHTCSQMLLT DMWMGRLRMR KNSGLKVILG ILLPPSILSL
810 820 830 840 850
EFKNKDDMPY MTQAQEIHLQ EKEPEEPEKP TKEKDEEDME LTAMLGRSNG
860 870 880 890 900
ESSRKKDEEE VQSRHRLIPV GRKIYEFYNA PIVKFWFYTL AYIGYLMLFN
910 920 930 940 950
YIVLVKMERW PSTQEWIVIS YIFTLGIEKM REILMSEPGK LLQKVKVWLQ
960 970 980 990 1000
EYWNVTDLIA ILLFSVGMIL RLQDQPFRSD GRVIYCVNII YWYIRLLDIF
1010 1020 1030 1040 1050
GVNKYLGPYV MMIGKMMIDM MYFVIIMLVV LMSFGVARQA ILFPNEEPSW
1060 1070 1080 1090 1100
KLAKNIFYMP YWMIYGEVFA DQIDPPCGQN ETREDGKTIQ LPPCKTGAWI
1110 1120 1130 1140 1150
VPAIMACYLL VANILLVNLL IAVFNNTFFE VKSISNQVWK FQRYQLIMTF
1160 1170 1180 1190 1200
HERPVLPPPL IIFSHMTMIF QHVCCRWRKH ESDQDERDYG LKLFITDDEL
1210 1220 1230 1240 1250
KKVHDFEEQC IEEYFREKDD RFNSSNDERI RVTSERVENM SMRLEEVNER
1260 1270 1280 1290 1300
EHSMKASLQT VDIRLAQLED LIGRMATALE RLTGLERAES NKIRSRTSSD
1310 1320 1330
CTDAAYIVRQ SSFNSQEGNT FKLQESIDPA EHPFYSV
Length:1,337
Mass (Da):154,069
Last modified:July 1, 2008 - v1
Checksum:i1A164537E3885CEF
GO

Computationally mapped potential isoform sequencesi

There are 5 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q5F4T0Q5F4T0_MOUSE
Transient receptor potential cation...
Trpm3
1,721Annotation score:
Q5F4S9Q5F4S9_MOUSE
Transient receptor potential cation...
Trpm3
1,721Annotation score:
Q5F4S8Q5F4S8_MOUSE
Transient receptor potential cation...
Trpm3
1,711Annotation score:
E9PUC8E9PUC8_MOUSE
Transient receptor potential cation...
Trpm3
958Annotation score:
D3Z539D3Z539_MOUSE
Transient receptor potential cation...
Trpm3
234Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC123066 Genomic DNA No translation available.
AC124513 Genomic DNA No translation available.
AC132389 Genomic DNA No translation available.
AC132454 Genomic DNA No translation available.
AC140411 Genomic DNA No translation available.
AC164427 Genomic DNA No translation available.
BC141400 mRNA Translation: AAI41401.1
BC141412 mRNA Translation: AAI41413.1
RefSeqiNP_796315.2, NM_177341.4
UniGeneiMm.131943
Mm.397699
Mm.440339

Genome annotation databases

EnsembliENSMUST00000037901; ENSMUSP00000042184; ENSMUSG00000052387
GeneIDi226025
UCSCiuc008gzo.1 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC123066 Genomic DNA No translation available.
AC124513 Genomic DNA No translation available.
AC132389 Genomic DNA No translation available.
AC132454 Genomic DNA No translation available.
AC140411 Genomic DNA No translation available.
AC164427 Genomic DNA No translation available.
BC141400 mRNA Translation: AAI41401.1
BC141412 mRNA Translation: AAI41413.1
RefSeqiNP_796315.2, NM_177341.4
UniGeneiMm.131943
Mm.397699
Mm.440339

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000037901; ENSMUSP00000042184; ENSMUSG00000052387
GeneIDi226025
UCSCiuc008gzo.1 mouse

Organism-specific databases

CTDi80036
MGIiMGI:2443101 Trpm3

Phylogenomic databases

eggNOGiKOG3614 Eukaryota
ENOG410XR5B LUCA
GeneTreeiENSGT00760000119127
HOGENOMiHOG000230920
HOVERGENiHBG055663

Enzyme and pathway databases

ReactomeiR-MMU-3295583 TRP channels

Miscellaneous databases

ChiTaRSiTrpm3 mouse
SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000052387 Expressed in 88 organ(s), highest expression level in pigmented layer of retina

Family and domain databases

Gene3Di1.20.5.1010, 1 hit
InterProiView protein in InterPro
IPR005821 Ion_trans_dom
IPR029583 TRPM3
IPR032415 TRPM_tetra
IPR037162 TRPM_tetra_sf
PANTHERiPTHR13800:SF7 PTHR13800:SF7, 1 hit
PfamiView protein in Pfam
PF00520 Ion_trans, 1 hit
PF16519 TRPM_tetra, 1 hit
ProtoNetiSearch...

Entry informationi

Entry nameiB2RUS0_MOUSE
AccessioniPrimary (citable) accession number: B2RUS0
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: September 12, 2018
This is version 79 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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