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Entry version 90 (22 Apr 2020)
Sequence version 2 (16 May 2012)
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Protein

Amyloid-beta A4 precursor protein-binding family A member 1

Gene

Apba1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the 'correct annotation' for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the 'protein existence' evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of AAP-beta (By similarity).By similarity

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Biological processProtein transport, Transport

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-212676 Dopamine Neurotransmitter Release Cycle

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
Amyloid-beta A4 precursor protein-binding family A member 1
Alternative name(s):
Adapter protein X11alpha
Neuron-specific X11 protein
Neuronal Munc18-1-interacting protein 1
Short name:
Mint-1
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: 'Name', 'Synonyms', 'Ordered locus names' and 'ORF names'.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Apba1
Synonyms:Mint1, X11
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the 'taxonomic identifier' or 'taxid'.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names%5Fand%5Ftaxonomy%5Fsection">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes%5Fmanual">proteome</a> can consist of several components.<br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 19

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1860297 Apba1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte & Seán O’Donoghue; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Golgi apparatus, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section describes the extent of a polypeptide chain in the mature protein following processing or proteolytic cleavage.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004175011 – 842Amyloid-beta A4 precursor protein-binding family A member 1Add BLAST842

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'PTM / Processing' section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei82PhosphoserineCombined sources1
Modified residuei246PhosphoserineCombined sources1
Modified residuei250PhosphoserineCombined sources1
Modified residuei252PhosphoserineCombined sources1
Modified residuei267PhosphoserineCombined sources1
Modified residuei284PhosphoserineCombined sources1
Modified residuei289PhosphoserineBy similarity1
Modified residuei309PhosphothreonineCombined sources1
Modified residuei317PhosphoserineCombined sources1
Modified residuei372PhosphoserineCombined sources1
Modified residuei375PhosphothreonineCombined sources1
Modified residuei406PhosphoserineCombined sources1
Modified residuei408PhosphoserineCombined sources1
Modified residuei413PhosphoserineCombined sources1
Modified residuei573PhosphoserineBy similarity1

Keywords - PTMi

Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
B2RUJ5

PaxDb, a database of protein abundance averages across all three domains of life

More...
PaxDbi
B2RUJ5

PeptideAtlas

More...
PeptideAtlasi
B2RUJ5

PRoteomics IDEntifications database

More...
PRIDEi
B2RUJ5

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
B2RUJ5

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
B2RUJ5

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

<p>This subsection of the 'Expression' section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms. By default, the information is derived from experiments at the mRNA level, unless specified 'at protein level'.<br></br>Examples: <a href="http://www.uniprot.org/uniprot/P92958#expression">P92958</a>, <a href="http://www.uniprot.org/uniprot/Q8TDN4#expression">Q8TDN4</a>, <a href="http://www.uniprot.org/uniprot/O14734#expression">O14734</a><p><a href='/help/tissue_specificity' target='_top'>More...</a></p>Tissue specificityi

Isoform 3 is expressed in brain.1 Publication

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000024897 Expressed in brain and 169 other tissues

Genevisible search portal to normalized and curated expression data from Genevestigator

More...
Genevisiblei
B2RUJ5 MM

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction%5Fsection">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function%5Fsection">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Part of a multimeric complex containing Munc18-1 and syntaxin-1. Also part of the brain-specific heterotrimeric complex LIN-10/X11-alpha, LIN-2/CASK, and LIN7. Binds to the cytoplasmic domain of amyloid protein (APP) (By similarity).

Interacts (via PDZ 1 and 2 domains) with FSPB (By similarity). Isoform 3 interacts (via its truncated PID domain) with active, GTP-bound RAB6A.

Also interacts with GTP-bound RAB6B (By similarity).

By similarity

GO - Molecular functioni

Protein-protein interaction databases

The Biological General Repository for Interaction Datasets (BioGrid)

More...
BioGridi
235626, 3 interactors

CORUM comprehensive resource of mammalian protein complexes

More...
CORUMi
B2RUJ5

The Eukaryotic Linear Motif resource for Functional Sites in Proteins

More...
ELMi
B2RUJ5

Protein interaction database and analysis system

More...
IntActi
B2RUJ5, 2 interactors

STRING: functional protein association networks

More...
STRINGi
10090.ENSMUSP00000025830

Miscellaneous databases

RNAct, Protein-RNA interaction predictions for model organisms.

More...
RNActi
B2RUJ5 protein

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family%5Fand%5Fdomains%5Fsection">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini460 – 648PIDPROSITE-ProRule annotationAdd BLAST189
Domaini661 – 746PDZ 1PROSITE-ProRule annotationAdd BLAST86
Domaini752 – 828PDZ 2PROSITE-ProRule annotationAdd BLAST77

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni631 – 648Autoinhibitory helix linkerBy similarityAdd BLAST18

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Family and Domains' section describes the position of regions of compositional bias within the protein and the particular amino acids that are over-represented within those regions.<p><a href='/help/compbias' target='_top'>More...</a></p>Compositional biasi40 – 67Pro-richAdd BLAST28
Compositional biasi298 – 334Pro-richAdd BLAST37
Compositional biasi373 – 457Pro-richAdd BLAST85

<p>This subsection of the 'Family and domains' section provides general information on the biological role of a domain. The term 'domain' is intended here in its wide acceptation, it may be a structural domain, a transmembrane region or a functional domain. Several domains are described in this subsection.<p><a href='/help/domain_cc' target='_top'>More...</a></p>Domaini

Composed of an N-terminal domain that binds Munc18-1 and LIN-2/CASK, a middle phosphotyrosine-binding domain (PID/PTB) that mediates binding with the cytoplasmic domain of the amyloid-beta precursor protein, and two C-terminal PDZ domains thought to attach proteins to the plasma membrane.By similarity
The autoinhibitory helix linker occludes the APP binding site.By similarity
The PID domain, truncated by 11 amino acids, as observed in isoform 3, but not full-length, mediates the interaction with RAB6A.By similarity

Keywords - Domaini

Repeat

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG3605 Eukaryota
ENOG410XSBD LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000156820

The HOGENOM Database of Homologous Genes from Fully Sequenced Organisms

More...
HOGENOMi
CLU_013563_1_0_1

InParanoid: Eukaryotic Ortholog Groups

More...
InParanoidi
B2RUJ5

KEGG Orthology (KO)

More...
KOi
K04531

Identification of Orthologs from Complete Genome Data

More...
OMAi
MNHLVGP

Database of Orthologous Groups

More...
OrthoDBi
436779at2759

Database for complete collections of gene phylogenies

More...
PhylomeDBi
B2RUJ5

TreeFam database of animal gene trees

More...
TreeFami
TF315245

Family and domain databases

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
2.30.29.30, 1 hit

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR030530 Apba1
IPR001478 PDZ
IPR036034 PDZ_sf
IPR011993 PH-like_dom_sf
IPR006020 PTB/PI_dom

The PANTHER Classification System

More...
PANTHERi
PTHR12345:SF14 PTHR12345:SF14, 1 hit

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00595 PDZ, 2 hits
PF00640 PID, 1 hit

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00228 PDZ, 2 hits
SM00462 PTB, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF50156 SSF50156, 2 hits

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS50106 PDZ, 2 hits
PS01179 PID, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence%5Flength">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>. The information is filed in different subsections. The current subsections and their content are listed below:<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequences (3)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences%5Fsection">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry describes 3 <p>This subsection of the 'Sequence' section lists the alternative protein sequences (isoforms) that can be generated from the same gene by a single or by the combination of up to four biological events (alternative promoter usage, alternative splicing, alternative initiation and ribosomal frameshifting). Additionally, this section gives relevant information on each alternative protein isoform. This section is only present in reviewed entries, i.e. in UniProtKB/Swiss-Prot.<p><a href='/help/alternative_products' target='_top'>More...</a></p> isoformsi produced by alternative splicing. AlignAdd to basket
Isoform 1 (identifier: B2RUJ5-1) [UniParc]FASTAAdd to basket

This isoform has been chosen as the <div> <p><b>What is the canonical sequence?</b><p><a href='/help/canonical_and_isoforms' target='_top'>More...</a></p>canonicali sequence. All positional information in this entry refers to it. This is also the sequence that appears in the downloadable versions of the entry.

« Hide
        10         20         30         40         50
MNHLEGSAEV EVADEAPGGE VNESVEADLE HPEVVEGQQP SPSPPPPAGH
60 70 80 90 100
EPEDHRGHPA PPPPPPPQEE EEEERGECLA RSASTESGFH NHTDTAEGDV
110 120 130 140 150
LAAARDGYEA ERAQDADDES AYAVQYRPEA EEYTEQAEAE HVEAAQRRAL
160 170 180 190 200
PNHLHFHSLE HEEAMNAAYS GYVYTHRLFH RAEDEPYAEP YADYGGLQEH
210 220 230 240 250
VYEEIGDAPE LEARDGLRLY ERERDEAAAY RQEALGARLH HYDERSDGES
260 270 280 290 300
DSPEKEAEFA PYPRMDSYEQ EEDIDQIVAE VKQSMSSQSL DKAAEDMPEA
310 320 330 340 350
EQDLERAPTP GGGHPDSPGL PAPAGQQQRV VGTPGGSEVG QRYSKEKRDA
360 370 380 390 400
ISLAIKDIKE AIEEVKTRTI RSPYTPDEPK EPIWVMRQDI SPTRDCDDQR
410 420 430 440 450
PVDGDSPSPG SSSPLGAESS SIPLHPGDPT EASTNKESRK SLASFPTYVE
460 470 480 490 500
VPGPCDPEDL IDGIIFAANY LGSTQLLSDK TPSKNVRMMQ AQEAVSRIKT
510 520 530 540 550
AQKLAKSRKK APEGESQPMT EVDLFISTQR IKVLNADTQE PMMDHPLRTI
560 570 580 590 600
SYIADIGNIV VLMARRRMPR SNSQENVEAS HPSQDGKRQY KMICHVFESE
610 620 630 640 650
DAQLIAQSIG QAFSVAYQEF LRANGINPED LSQKEYSDLL NTQDMYNDDL
660 670 680 690 700
IHFSKSENCK DVFIEKQKGE ILGVVIVESG WGSILPTVII ANMMHGGPAE
710 720 730 740 750
KSGKLNIGDQ IMSINGTSLV GLPLSTCQSI IKGLKNQSRV KLNIVRCPPV
760 770 780 790 800
TTVLIRRPDL RYQLGFSVQN GIICSLMRGG IAERGGVRVG HRIIEINGQS
810 820 830 840
VVATPHEKIV HILSNAVGEI HMKTMPAAMY RLLTAQEQPV YI
Length:842
Mass (Da):92,909
Last modified:May 16, 2012 - v2
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:iE00B754EDCF1B1D4
GO
Isoform 2 (identifier: B2RUJ5-2) [UniParc]FASTAAdd to basket

The sequence of this isoform differs from the canonical sequence as follows:
     1-390: Missing.
     391-405: SPTRDCDDQRPVDGD → MENFWMYQFESHEEE

Show »
Length:452
Mass (Da):49,936
Checksum:i2C9FA41FD7FCF340
GO
Isoform 3 (identifier: B2RUJ5-3) [UniParc]FASTAAdd to basket
Also known as: Mint1_826

The sequence of this isoform differs from the canonical sequence as follows:
     500-510: Missing.

Note: This isoform interacts with RAB6 GTPases.Curated
Show »
Length:831
Mass (Da):91,669
Checksum:i170DDCF2204F0C86
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section reports difference(s) between the canonical sequence (displayed by default in the entry) and the different sequence submissions merged in the entry. These various submissions may originate from different sequencing projects, different types of experiments, or different biological samples. Sequence conflicts are usually of unknown origin.<p><a href='/help/conflict' target='_top'>More...</a></p>Sequence conflicti142V → A in AAI41182 (PubMed:15489334).Curated1

Alternative sequence

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the 'Sequence' section describes the sequence of naturally occurring alternative protein isoform(s). The changes in the amino acid sequence may be due to alternative splicing, alternative promoter usage, alternative initiation, or ribosomal frameshifting.<p><a href='/help/var_seq' target='_top'>More...</a></p>Alternative sequenceiVSP_0437631 – 390Missing in isoform 2. 1 PublicationAdd BLAST390
Alternative sequenceiVSP_043764391 – 405SPTRD…PVDGD → MENFWMYQFESHEEE in isoform 2. 1 PublicationAdd BLAST15
Alternative sequenceiVSP_053519500 – 510Missing in isoform 3. CuratedAdd BLAST11

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

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EMBLi

GenBank nucleotide sequence database

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GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AK032261 mRNA Translation: BAC27784.1
AK147583 mRNA Translation: BAE28008.1
AC134830 Genomic DNA No translation available.
AC148021 Genomic DNA No translation available.
CH466534 Genomic DNA Translation: EDL41607.1
CH466534 Genomic DNA Translation: EDL41608.1
BC141181 mRNA Translation: AAI41182.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS50407.1 [B2RUJ5-1]

NCBI Reference Sequences

More...
RefSeqi
NP_796008.2, NM_177034.3 [B2RUJ5-1]
XP_006527202.1, XM_006527139.3 [B2RUJ5-1]
XP_006527203.1, XM_006527140.3 [B2RUJ5-3]

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000025830; ENSMUSP00000025830; ENSMUSG00000024897 [B2RUJ5-1]
ENSMUST00000237688; ENSMUSP00000157770; ENSMUSG00000024897 [B2RUJ5-2]

Database of genes from NCBI RefSeq genomes

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GeneIDi
319924

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:319924

UCSC genome browser

More...
UCSCi
uc008hai.1 mouse [B2RUJ5-1]

Keywords - Coding sequence diversityi

Alternative splicing

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK032261 mRNA Translation: BAC27784.1
AK147583 mRNA Translation: BAE28008.1
AC134830 Genomic DNA No translation available.
AC148021 Genomic DNA No translation available.
CH466534 Genomic DNA Translation: EDL41607.1
CH466534 Genomic DNA Translation: EDL41608.1
BC141181 mRNA Translation: AAI41182.1
CCDSiCCDS50407.1 [B2RUJ5-1]
RefSeqiNP_796008.2, NM_177034.3 [B2RUJ5-1]
XP_006527202.1, XM_006527139.3 [B2RUJ5-1]
XP_006527203.1, XM_006527140.3 [B2RUJ5-3]

3D structure databases

Database of comparative protein structure models

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ModBasei
Search...

SWISS-MODEL Interactive Workspace

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SWISS-MODEL-Workspacei
Submit a new modelling project...

Protein-protein interaction databases

BioGridi235626, 3 interactors
CORUMiB2RUJ5
ELMiB2RUJ5
IntActiB2RUJ5, 2 interactors
STRINGi10090.ENSMUSP00000025830

PTM databases

iPTMnetiB2RUJ5
PhosphoSitePlusiB2RUJ5

Proteomic databases

jPOSTiB2RUJ5
PaxDbiB2RUJ5
PeptideAtlasiB2RUJ5
PRIDEiB2RUJ5

Protocols and materials databases

Antibodypedia a portal for validated antibodies

More...
Antibodypediai
12360 206 antibodies

Genome annotation databases

EnsembliENSMUST00000025830; ENSMUSP00000025830; ENSMUSG00000024897 [B2RUJ5-1]
ENSMUST00000237688; ENSMUSP00000157770; ENSMUSG00000024897 [B2RUJ5-2]
GeneIDi319924
KEGGimmu:319924
UCSCiuc008hai.1 mouse [B2RUJ5-1]

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
320
MGIiMGI:1860297 Apba1

Phylogenomic databases

eggNOGiKOG3605 Eukaryota
ENOG410XSBD LUCA
GeneTreeiENSGT00940000156820
HOGENOMiCLU_013563_1_0_1
InParanoidiB2RUJ5
KOiK04531
OMAiMNHLVGP
OrthoDBi436779at2759
PhylomeDBiB2RUJ5
TreeFamiTF315245

Enzyme and pathway databases

ReactomeiR-MMU-212676 Dopamine Neurotransmitter Release Cycle

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

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ChiTaRSi
Apba1 mouse

Protein Ontology

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PROi
PR:B2RUJ5
RNActiB2RUJ5 protein

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000024897 Expressed in brain and 169 other tissues
GenevisibleiB2RUJ5 MM

Family and domain databases

Gene3Di2.30.29.30, 1 hit
InterProiView protein in InterPro
IPR030530 Apba1
IPR001478 PDZ
IPR036034 PDZ_sf
IPR011993 PH-like_dom_sf
IPR006020 PTB/PI_dom
PANTHERiPTHR12345:SF14 PTHR12345:SF14, 1 hit
PfamiView protein in Pfam
PF00595 PDZ, 2 hits
PF00640 PID, 1 hit
SMARTiView protein in SMART
SM00228 PDZ, 2 hits
SM00462 PTB, 1 hit
SUPFAMiSSF50156 SSF50156, 2 hits
PROSITEiView protein in PROSITE
PS50106 PDZ, 2 hits
PS01179 PID, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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ProtoNeti
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MobiDB: a database of protein disorder and mobility annotations

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MobiDBi
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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the 'Entry information' section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiAPBA1_MOUSE
<p>This subsection of the 'Entry information' section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called 'Primary (citable) accession number'.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B2RUJ5
Secondary accession number(s): Q3UH49, Q8BMF2
<p>This subsection of the 'Entry information' section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification ('Last modified'). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical%5Fand%5Fisoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 16, 2012
Last sequence update: May 16, 2012
Last modified: April 22, 2020
This is version 90 of the entry and version 2 of the sequence. See complete history.
<p>This subsection of the 'Entry information' section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn't fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Direct protein sequencing, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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