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Protein
Submitted name:

Potassium voltage-gated channel, shaker-related subfamily, member 7

Gene

KCNA7

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionIon channel, Potassium channelSAAS annotation, Voltage-gated channelSAAS annotation
Biological processIon transport, Potassium transport, Transport
LigandPotassium

Names & Taxonomyi

Protein namesi
Submitted name:
Potassium voltage-gated channel, shaker-related subfamily, member 7Imported
Gene namesi
Name:KCNA7Imported
ORF Names:hCG_16229Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei144 – 165HelicalSequence analysisAdd BLAST22
Transmembranei209 – 229HelicalSequence analysisAdd BLAST21
Transmembranei312 – 333HelicalSequence analysisAdd BLAST22
Transmembranei373 – 394HelicalSequence analysisAdd BLAST22

Keywords - Cellular componenti

Membrane

PTM / Processingi

Proteomic databases

PRIDEiB2RU13

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini13 – 113BTBInterPro annotationAdd BLAST101

Sequence similaritiesi

Belongs to the potassium channel family.SAAS annotation

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysisSAAS annotation

Phylogenomic databases

eggNOGiKOG1545 Eukaryota
COG1226 LUCA
HOVERGENiHBG052230

Family and domain databases

Gene3Di1.20.120.350, 1 hit
InterProiView protein in InterPro
IPR000210 BTB/POZ_dom
IPR005821 Ion_trans_dom
IPR003968 K_chnl_volt-dep_Kv
IPR003972 K_chnl_volt-dep_Kv1
IPR011333 SKP1/BTB/POZ_sf
IPR003131 T1-type_BTB
IPR028325 VG_K_chnl
IPR027359 Volt_channel_dom_sf
PANTHERiPTHR11537 PTHR11537, 1 hit
PfamiView protein in Pfam
PF02214 BTB_2, 1 hit
PF00520 Ion_trans, 1 hit
PRINTSiPR00169 KCHANNEL
PR01491 KVCHANNEL
PR01496 SHAKERCHANEL
SMARTiView protein in SMART
SM00225 BTB, 1 hit
SUPFAMiSSF54695 SSF54695, 1 hit

Sequencei

Sequence statusi: Complete.

B2RU13-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEPRCPPPCG CCERLVLNVA GLRFETRART LGRFPDTLLG DPARRGRFYD
60 70 80 90 100
DARREYFFDR HRPSFDAVLY YYQSGGRLRR PAHVPLDVFL EEVAFYGLGA
110 120 130 140 150
AALARLREDE GCPVPPERPL PRRAFARQLW LLFEFPESSQ AARVLAVVSV
160 170 180 190 200
LVILVSIVVF CLETLPDFRD DRDGTGLAAA AAAGPFPARL NGSSQMPGNP
210 220 230 240 250
PRLPFNDPFF VVETLCICWF SFELLVRLLV CPSKAIFFKN VMNLIDFVAI
260 270 280 290 300
LPYFVALGTE LARQRGVGQQ AMSLAILRVI RLVRVFRIFK LSRHSKGLQI
310 320 330 340 350
LGQTLRASMR ELGLLIFFLF IGVVLFSSAV YFAEVDRVDS HFTSIPESFW
360 370 380 390 400
WAVVTMTTVG YGDMAPVTVG GKIVGSLCAI AGVLTISLPV PVIVSNFSYF
410 420 430 440 450
YHRETEGEEA GMFSHVDTQP CGPLEGKANG GLVDGEVPEL PPPLWAPPGK

HLVTEV
Length:456
Mass (Da):50,588
Last modified:July 1, 2008 - v1
Checksum:i95B680CFFEF739FB
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC140906 mRNA Translation: AAI40907.1
CH471177 Genomic DNA Translation: EAW52444.1
UniGeneiHs.306973

Similar proteinsi

Entry informationi

Entry nameiB2RU13_HUMAN
AccessioniPrimary (citable) accession number: B2RU13
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: May 23, 2018
This is version 73 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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