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Protein
Submitted name:

Apolipoprotein L 7a

Gene

Apol7a

Organism
Mus musculus (Mouse)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  • lipid binding Source: GO_Central

GO - Biological processi

Enzyme and pathway databases

ReactomeiR-MMU-2168880 Scavenging of heme from plasma
R-MMU-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-MMU-8957275 Post-translational protein phosphorylation

Names & Taxonomyi

Protein namesi
Submitted name:
Apolipoprotein L 7aImported
Submitted name:
MCG23624, isoform CRA_aImported
Gene namesi
Name:Apol7aImported
ORF Names:mCG_23624Imported
OrganismiMus musculus (Mouse)Imported
Taxonomic identifieri10090 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
Proteomesi
  • UP000000589 Componenti: Chromosome 15

Organism-specific databases

MGIiMGI:1923011 Apol7a

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Keywords - PTMi

LipoproteinImported

Expressioni

Gene expression databases

BgeeiENSMUSG00000010601 Expressed in 61 organ(s), highest expression level in intestine

Interactioni

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000010745

Family & Domainsi

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili385 – 418Sequence analysisAdd BLAST34

Keywords - Domaini

Coiled coilSequence analysis

Phylogenomic databases

eggNOGiENOG410IWES Eukaryota
ENOG410Y0AF LUCA
GeneTreeiENSGT00510000046700
HOGENOMiHOG000294132
HOVERGENiHBG074468
KOiK14480
OMAiVQKVHKG
OrthoDBiEOG091G0MIQ
TreeFamiTF334681

Family and domain databases

InterProiView protein in InterPro
IPR008405 ApoL
PANTHERiPTHR14096 PTHR14096, 2 hits
PfamiView protein in Pfam
PF05461 ApoL, 2 hits

Sequence (1+)i

Sequence statusi: Complete.

This entry has 1 described isoform and 1 potential isoform that is computationally mapped.Show allAlign All

B2RT54-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MDTPDRECFV ESVVNYLLDT WSTEDLRLLL TEEETWKHFV AEVDLSREEE
60 70 80 90 100
AALQESLAEI FADPDGEDED ELQNDLQDKN ERKEEDSLSE DLGESVADTD
110 120 130 140 150
VEDEDGDAED EDSDTEDEDR DIEDENSNRE DEDSDTEDED SDTEGEDSNT
160 170 180 190 200
EDEEEIQNDL WHKERFLDAY PQVKLELEEI IRKLHALADK VDKVHRDCTI
210 220 230 240 250
SRVVASSSSA VSGVLIILGL SLAPVTAGVS LALSATGLGL GAAAAVTSVS
260 270 280 290 300
TSIVEKVSVV SAEDEASKLV PTNKDTMKGM KEVLDQSGPR LLSLSTDTIQ
310 320 330 340 350
RLQGIQKCIN AIPLAKANTR LANNAKRLMT TGKISARNTK QVQKAFGGTA
360 370 380 390 400
LAMTKGARIM GAATAGFFLL QDVISLVEDS KHLHEGAKSQ TAAELRKQAQ
410
DLEQKLQELK EVHDSLTK
Length:418
Mass (Da):45,910
Last modified:July 1, 2008 - v1
Checksum:i2C50374755993DBD
GO

Computationally mapped potential isoform sequencesi

There is 1 potential isoform mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
H3BKF5H3BKF5_MOUSE
Apolipoprotein L 7a
Apol7a
44Annotation score:

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL772386 Genomic DNA No translation available.
BC139137 mRNA Translation: AAI39138.1
BC139138 mRNA Translation: AAI39139.1
CH466545 Genomic DNA Translation: EDL29636.1
CH466545 Genomic DNA Translation: EDL29637.1
RefSeqiNP_001158112.1, NM_001164640.1
NP_083695.2, NM_029419.2
XP_011244068.1, XM_011245766.1
UniGeneiMm.232636

Genome annotation databases

EnsembliENSMUST00000010745; ENSMUSP00000010745; ENSMUSG00000010601
ENSMUST00000175919; ENSMUSP00000135864; ENSMUSG00000010601
ENSMUST00000176074; ENSMUSP00000134864; ENSMUSG00000010601
GeneIDi75761
KEGGimmu:75761
UCSCiuc007wnl.2 mouse

Similar proteinsi

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL772386 Genomic DNA No translation available.
BC139137 mRNA Translation: AAI39138.1
BC139138 mRNA Translation: AAI39139.1
CH466545 Genomic DNA Translation: EDL29636.1
CH466545 Genomic DNA Translation: EDL29637.1
RefSeqiNP_001158112.1, NM_001164640.1
NP_083695.2, NM_029419.2
XP_011244068.1, XM_011245766.1
UniGeneiMm.232636

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi10090.ENSMUSP00000010745

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000010745; ENSMUSP00000010745; ENSMUSG00000010601
ENSMUST00000175919; ENSMUSP00000135864; ENSMUSG00000010601
ENSMUST00000176074; ENSMUSP00000134864; ENSMUSG00000010601
GeneIDi75761
KEGGimmu:75761
UCSCiuc007wnl.2 mouse

Organism-specific databases

CTDi75761
MGIiMGI:1923011 Apol7a

Phylogenomic databases

eggNOGiENOG410IWES Eukaryota
ENOG410Y0AF LUCA
GeneTreeiENSGT00510000046700
HOGENOMiHOG000294132
HOVERGENiHBG074468
KOiK14480
OMAiVQKVHKG
OrthoDBiEOG091G0MIQ
TreeFamiTF334681

Enzyme and pathway databases

ReactomeiR-MMU-2168880 Scavenging of heme from plasma
R-MMU-381426 Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)
R-MMU-8957275 Post-translational protein phosphorylation

Miscellaneous databases

SOURCEiSearch...

Gene expression databases

BgeeiENSMUSG00000010601 Expressed in 61 organ(s), highest expression level in intestine

Family and domain databases

InterProiView protein in InterPro
IPR008405 ApoL
PANTHERiPTHR14096 PTHR14096, 2 hits
PfamiView protein in Pfam
PF05461 ApoL, 2 hits
ProtoNetiSearch...

Entry informationi

Entry nameiB2RT54_MOUSE
AccessioniPrimary (citable) accession number: B2RT54
Secondary accession number(s): E9Q635
Entry historyiIntegrated into UniProtKB/TrEMBL: July 1, 2008
Last sequence update: July 1, 2008
Last modified: November 7, 2018
This is version 76 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Proteomics identificationCombined sources, Reference proteomeImported
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health

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