UniProtKB - B2RRL2 (JERKL_MOUSE)
Protein
Jerky protein homolog-like
Gene
Jrkl
Organism
Mus musculus (Mouse)
Status
Functioni
Regions
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
DNA bindingi | 28 – 48 | H-T-H motifBy similarityAdd BLAST | 21 | |
DNA bindingi | 100 – 132 | H-T-H motifBy similarityAdd BLAST | 33 |
GO - Molecular functioni
- DNA binding Source: GO_Central
Keywordsi
Molecular function | DNA-binding |
Names & Taxonomyi
Protein namesi | Recommended name: Jerky protein homolog-like |
Gene namesi | Name:Jrkl |
Organismi | Mus musculus (Mouse) |
Taxonomic identifieri | 10090 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Glires › Rodentia › Myomorpha › Muroidea › Muridae › Murinae › Mus › Mus |
Proteomesi |
|
Organism-specific databases
MGIi | MGI:1924782, Jrkl |
Subcellular locationi
Nucleus
- Nucleus PROSITE-ProRule annotation
Nucleus
- nucleus Source: GO_Central
Keywords - Cellular componenti
NucleusPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000379975 | 1 – 523 | Jerky protein homolog-likeAdd BLAST | 523 |
Proteomic databases
EPDi | B2RRL2 |
jPOSTi | B2RRL2 |
PaxDbi | B2RRL2 |
PeptideAtlasi | B2RRL2 |
PRIDEi | B2RRL2 |
ProteomicsDBi | 301697 |
PTM databases
iPTMneti | B2RRL2 |
PhosphoSitePlusi | B2RRL2 |
Expressioni
Gene expression databases
Bgeei | ENSMUSG00000079083, Expressed in granulocyte and 55 other tissues |
Interactioni
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000128798 |
Miscellaneous databases
RNActi | B2RRL2, protein |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 1 – 52 | HTH psq-typePROSITE-ProRule annotationAdd BLAST | 52 | |
Domaini | 67 – 139 | HTH CENPB-typePROSITE-ProRule annotationAdd BLAST | 73 | |
Domaini | 168 – 385 | DDE-1Sequence analysisAdd BLAST | 218 |
Sequence similaritiesi
Belongs to the tigger transposable element derived protein family.Curated
Phylogenomic databases
eggNOGi | KOG3105, Eukaryota |
GeneTreei | ENSGT00940000161513 |
HOGENOMi | CLU_018294_1_1_1 |
InParanoidi | B2RRL2 |
OMAi | VSGPICA |
OrthoDBi | 1343623at2759 |
PhylomeDBi | B2RRL2 |
TreeFami | TF101131 |
Family and domain databases
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR004875, DDE_SF_endonuclease_dom IPR009057, Homeobox-like_sf IPR006600, HTH_CenpB_DNA-bd_dom IPR007889, HTH_Psq IPR036388, WH-like_DNA-bd_sf |
Pfami | View protein in Pfam PF04218, CENP-B_N, 1 hit PF03184, DDE_1, 1 hit PF03221, HTH_Tnp_Tc5, 1 hit |
SMARTi | View protein in SMART SM00674, CENPB, 1 hit |
SUPFAMi | SSF46689, SSF46689, 2 hits |
PROSITEi | View protein in PROSITE PS51253, HTH_CENPB, 1 hit PS50960, HTH_PSQ, 1 hit |
i Sequence
Sequence statusi: Complete.
B2RRL2-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSGKRKRVVL TIKDKLDIIK KLEDGGSSKQ LAVIYGIGET TVRDIRKNKE
60 70 80 90 100
KIITYASSSD STSLLAKRKS MKPSMYEELD KAMLEWFNQQ RAKGNPISGP
110 120 130 140 150
ICAKRAEFFF YALGMDGDFN PSAGWLTRFK QRHSIREINI RNERLNGDET
160 170 180 190 200
AVEDFCNNFR DFIEQENLQP EQIYNADETG LFWKCLPSRT TVIKGKCTVP
210 220 230 240 250
GHNLGEERIT VMCCTNATGL HKLKLCVVGK ARKPRSFKST DTLNLPVSYF
260 270 280 290 300
SQKGAWMDLS IFRQWFDKIF VPQVREYLRS KGLQEKAVLL LDNSPTHPNE
310 320 330 340 350
NVLRSDDGQI FAKYLPPNVA SLIQPLGQGV IAAMKRNYRA GLLHNNLEEG
360 370 380 390 400
NDLKSFWKKL TLLDALYEIA MAWNLVKPVT ISRAWKQILP AIEEKEGLDF
410 420 430 440 450
DEDISGATVA TILQHTKGLE NVTPENLEKW LEIDSTEPGY EVLTDSEIIR
460 470 480 490 500
RAQGQTDESS ENDEERIELI PEKHINHTTA LQWTENLLDY LEQQGDMILP
510 520
DRLVIRKLRA TIRNKQKMTN PGQ
Sequence cautioni
The sequence BAE43369 differs from that shown. Reason: Frameshift.Curated
The sequence BAE43369 differs from that shown. Reason: Erroneous initiation. Truncated N-terminus.Curated
Experimental Info
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Sequence conflicti | 506 | R → T in BAE43369 (PubMed:16141072).Curated | 1 | |
Sequence conflicti | 515 | K → R in BAE43369 (PubMed:16141072).Curated | 1 | |
Sequence conflicti | 520 | N → T in BAE43369 (PubMed:16141072).Curated | 1 |
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH466522 Genomic DNA Translation: EDL24967.1 BC138472 mRNA Translation: AAI38473.1 BC138475 mRNA Translation: AAI38476.1 AK079877 mRNA Translation: BAE43369.1 Sequence problems. |
CCDSi | CCDS57650.1 |
RefSeqi | NP_001028353.1, NM_001033181.1 |
Genome annotation databases
Ensembli | ENSMUST00000110582; ENSMUSP00000128798; ENSMUSG00000079083 |
GeneIDi | 77532 |
KEGGi | mmu:77532 |
UCSCi | uc012hdj.1, mouse |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | CH466522 Genomic DNA Translation: EDL24967.1 BC138472 mRNA Translation: AAI38473.1 BC138475 mRNA Translation: AAI38476.1 AK079877 mRNA Translation: BAE43369.1 Sequence problems. |
CCDSi | CCDS57650.1 |
RefSeqi | NP_001028353.1, NM_001033181.1 |
3D structure databases
SMRi | B2RRL2 |
ModBasei | Search... |
Protein-protein interaction databases
STRINGi | 10090.ENSMUSP00000128798 |
PTM databases
iPTMneti | B2RRL2 |
PhosphoSitePlusi | B2RRL2 |
Proteomic databases
EPDi | B2RRL2 |
jPOSTi | B2RRL2 |
PaxDbi | B2RRL2 |
PeptideAtlasi | B2RRL2 |
PRIDEi | B2RRL2 |
ProteomicsDBi | 301697 |
Protocols and materials databases
Antibodypediai | 31694, 115 antibodies |
Genome annotation databases
Ensembli | ENSMUST00000110582; ENSMUSP00000128798; ENSMUSG00000079083 |
GeneIDi | 77532 |
KEGGi | mmu:77532 |
UCSCi | uc012hdj.1, mouse |
Organism-specific databases
CTDi | 8690 |
MGIi | MGI:1924782, Jrkl |
Phylogenomic databases
eggNOGi | KOG3105, Eukaryota |
GeneTreei | ENSGT00940000161513 |
HOGENOMi | CLU_018294_1_1_1 |
InParanoidi | B2RRL2 |
OMAi | VSGPICA |
OrthoDBi | 1343623at2759 |
PhylomeDBi | B2RRL2 |
TreeFami | TF101131 |
Miscellaneous databases
BioGRID-ORCSi | 77532, 0 hits in 52 CRISPR screens |
PROi | PR:B2RRL2 |
RNActi | B2RRL2, protein |
SOURCEi | Search... |
Gene expression databases
Bgeei | ENSMUSG00000079083, Expressed in granulocyte and 55 other tissues |
Family and domain databases
Gene3Di | 1.10.10.10, 1 hit |
InterProi | View protein in InterPro IPR004875, DDE_SF_endonuclease_dom IPR009057, Homeobox-like_sf IPR006600, HTH_CenpB_DNA-bd_dom IPR007889, HTH_Psq IPR036388, WH-like_DNA-bd_sf |
Pfami | View protein in Pfam PF04218, CENP-B_N, 1 hit PF03184, DDE_1, 1 hit PF03221, HTH_Tnp_Tc5, 1 hit |
SMARTi | View protein in SMART SM00674, CENPB, 1 hit |
SUPFAMi | SSF46689, SSF46689, 2 hits |
PROSITEi | View protein in PROSITE PS51253, HTH_CENPB, 1 hit PS50960, HTH_PSQ, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | JERKL_MOUSE | |
Accessioni | B2RRL2Primary (citable) accession number: B2RRL2 Secondary accession number(s): Q3V2Y6 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | July 28, 2009 |
Last sequence update: | July 1, 2008 | |
Last modified: | April 7, 2021 | |
This is version 83 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Chordata Protein Annotation Program |
Miscellaneousi
Keywords - Technical termi
Reference proteomeDocuments
- MGD cross-references
Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot - SIMILARITY comments
Index of protein domains and families