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Entry version 94 (16 Jan 2019)
Sequence version 1 (01 Jul 2008)
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Protein

Peregrin

Gene

Brpf1

Organism
Mus musculus (Mouse)
Status
Reviewed-Annotation score:

Annotation score:5 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
-Experimental evidence at protein leveli <p>This indicates the type of evidence that supports the existence of the protein. Note that the ‘protein existence’ evidence does not give information on the accuracy or correctness of the sequence(s) displayed.<p><a href='/help/protein_existence' target='_top'>More...</a></p>

<p>This section provides any useful information about the protein, mostly biological knowledge.<p><a href='/help/function_section' target='_top'>More...</a></p>Functioni

Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Preferentially mediates histone H3-K23 acetylation (PubMed:27939640). Positively regulates the transcription of RUNX1 and RUNX2 (By similarity).By similarity1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Function’ section specifies the position(s) and type(s) of zinc fingers within the protein.<p><a href='/help/zn_fing' target='_top'>More...</a></p>Zinc fingeri21 – 47C2H2-typePROSITE-ProRule annotationAdd BLAST27
Zinc fingeri272 – 322PHD-type 1PROSITE-ProRule annotationAdd BLAST51
Zinc fingeri326 – 359C2HC pre-PHD-typePROSITE-ProRule annotationAdd BLAST34
Zinc fingeri383 – 447PHD-type 2PROSITE-ProRule annotationAdd BLAST65

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:<p><a href='/help/gene_ontology' target='_top'>More...</a></p>GO - Molecular functioni

GO - Biological processi

<p>UniProtKB Keywords constitute a <a href="http://www.uniprot.org/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='/help/keywords' target='_top'>More...</a></p>Keywordsi

Molecular functionActivator, Chromatin regulator, DNA-binding
Biological processTranscription, Transcription regulation
LigandMetal-binding, Zinc

Enzyme and pathway databases

Reactome - a knowledgebase of biological pathways and processes

More...
Reactomei
R-MMU-3214847 HATs acetylate histones
R-MMU-6804758 Regulation of TP53 Activity through Acetylation

<p>This section provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.<p><a href='/help/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyi

<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides an exhaustive list of all names of the protein, from commonly used to obsolete, to allow unambiguous identification of a protein.<p><a href='/help/protein_names' target='_top'>More...</a></p>Protein namesi
Recommended name:
PeregrinCurated
Alternative name(s):
Bromodomain and PHD finger-containing protein 1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section indicates the name(s) of the gene(s) that code for the protein sequence(s) described in the entry. Four distinct tokens exist: ‘Name’, ‘Synonyms’, ‘Ordered locus names’ and ‘ORF names’.<p><a href='/help/gene_name' target='_top'>More...</a></p>Gene namesi
Name:Brpf1Imported
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section provides information on the name(s) of the organism that is the source of the protein sequence.<p><a href='/help/organism-name' target='_top'>More...</a></p>OrganismiMus musculus (Mouse)
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section shows the unique identifier assigned by the NCBI to the source organism of the protein. This is known as the ‘taxonomic identifier’ or ‘taxid’.<p><a href='/help/taxonomic_identifier' target='_top'>More...</a></p>Taxonomic identifieri10090 [NCBI]
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section contains the taxonomic hierarchical classification lineage of the source organism. It lists the nodes as they appear top-down in the taxonomic tree, with the more general grouping listed first.<p><a href='/help/taxonomic_lineage' target='_top'>More...</a></p>Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresGliresRodentiaMyomorphaMuroideaMuridaeMurinaeMusMus
<p>This subsection of the <a href="http://www.uniprot.org/help/names_and_taxonomy_section">Names and taxonomy</a> section is present for entries that are part of a <a href="http://www.uniprot.org/proteomes">proteome</a>, i.e. of a set of proteins thought to be expressed by organisms whose genomes have been completely sequenced.<p><a href='/help/proteomes_manual' target='_top'>More...</a></p>Proteomesi
  • UP000000589 <p>A UniProt <a href="http://www.uniprot.org/manual/proteomes_manual">proteome</a> can consist of several components. <br></br>The component name refers to the genomic component encoding a set of proteins.<p><a href='/help/proteome_component' target='_top'>More...</a></p> Componenti: Chromosome 6

Organism-specific databases

Mouse genome database (MGD) from Mouse Genome Informatics (MGI)

More...
MGIi
MGI:1926033 Brpf1

<p>This section provides information on the location and the topology of the mature protein in the cell.<p><a href='/help/subcellular_location_section' target='_top'>More...</a></p>Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm, Nucleus

<p>This section describes post-translational modifications (PTMs) and/or processing events.<p><a href='/help/ptm_processing_section' target='_top'>More...</a></p>PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section describes the extent of a polypeptide chain in the mature protein following processing.<p><a href='/help/chain' target='_top'>More...</a></p>ChainiPRO_00004398131 – 1212PeregrinAdd BLAST1212

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘PTM / Processing’ section specifies the position and type of each modified residue excluding <a href="http://www.uniprot.org/manual/lipid">lipids</a>, <a href="http://www.uniprot.org/manual/carbohyd">glycans</a> and <a href="http://www.uniprot.org/manual/crosslnk">protein cross-links</a>.<p><a href='/help/mod_res' target='_top'>More...</a></p>Modified residuei120PhosphoserineCombined sources1
Modified residuei147N6-acetyllysineCombined sources1
Modified residuei237PhosphoserineBy similarity1
Modified residuei459PhosphoserineCombined sources1
Modified residuei461PhosphoserineCombined sources1
Modified residuei579N6-acetyllysineCombined sources1
Modified residuei856PhosphothreonineCombined sources1
Modified residuei858PhosphoserineCombined sources1
Modified residuei915PhosphoserineCombined sources1
Modified residuei920PhosphoserineCombined sources1
Modified residuei924PhosphoserineCombined sources1
Modified residuei1074PhosphoserineBy similarity1
Modified residuei1185PhosphoserineBy similarity1

<p>This subsection of the <a href="http://www.uniprot.org/help/ptm_processing_section">PTM/processing</a> section describes post-translational modifications (PTMs). This subsection <strong>complements</strong> the information provided at the sequence level or describes modifications for which <strong>position-specific data is not yet available</strong>.<p><a href='/help/post-translational_modification' target='_top'>More...</a></p>Post-translational modificationi

Acetylated by KAT6A.By similarity

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

jPOST - Japan Proteome Standard Repository/Database

More...
jPOSTi
B2RRD7

MaxQB - The MaxQuant DataBase

More...
MaxQBi
B2RRD7

PeptideAtlas

More...
PeptideAtlasi
B2RRD7

PRoteomics IDEntifications database

More...
PRIDEi
B2RRD7

PTM databases

iPTMnet integrated resource for PTMs in systems biology context

More...
iPTMneti
B2RRD7

Comprehensive resource for the study of protein post-translational modifications (PTMs) in human, mouse and rat.

More...
PhosphoSitePlusi
B2RRD7

<p>This section provides information on the expression of a gene at the mRNA or protein level in cells or in tissues of multicellular organisms.<p><a href='/help/expression_section' target='_top'>More...</a></p>Expressioni

Gene expression databases

Bgee dataBase for Gene Expression Evolution

More...
Bgeei
ENSMUSG00000001632 Expressed in 283 organ(s), highest expression level in humerus cartilage element

ExpressionAtlas, Differential and Baseline Expression

More...
ExpressionAtlasi
B2RRD7 baseline and differential

<p>This section provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.<p><a href='/help/interaction_section' target='_top'>More...</a></p>Interactioni

<p>This subsection of the <a href="http://www.uniprot.org/help/interaction_section">'Interaction'</a> section provides information about the protein quaternary structure and interaction(s) with other proteins or protein complexes (with the exception of physiological receptor-ligand interactions which are annotated in the <a href="http://www.uniprot.org/help/function_section">'Function'</a> section).<p><a href='/help/subunit_structure' target='_top'>More...</a></p>Subunit structurei

Component of the MOZ/MORF complex composed at least of ING5, KAT6A, KAT6B, MEAF6 and one of BRPF1, BRD1/BRPF2 and BRPF3. Interacts with trimethylated 'Lys-36' of histone H3 (H3K36me3). May interact with KAT7.By similarity

<p>This section provides information on the tertiary and secondary structure of a protein.<p><a href='/help/structure_section' target='_top'>More...</a></p>Structurei

3D structure databases

Protein Model Portal of the PSI-Nature Structural Biology Knowledgebase

More...
ProteinModelPortali
B2RRD7

SWISS-MODEL Repository - a database of annotated 3D protein structure models

More...
SMRi
B2RRD7

Database of comparative protein structure models

More...
ModBasei
Search...

MobiDB: a database of protein disorder and mobility annotations

More...
MobiDBi
Search...

<p>This section provides information on sequence similarities with other proteins and the domain(s) present in a protein.<p><a href='/help/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the <a href="http://www.uniprot.org/help/family_and_domains_section">Family and Domains</a> section describes the position and type of a domain, which is defined as a specific combination of secondary structures organized into a characteristic three-dimensional structure or fold.<p><a href='/help/domain' target='_top'>More...</a></p>Domaini644 – 714BromoPROSITE-ProRule annotationAdd BLAST71
Domaini1083 – 1166PWWPPROSITE-ProRule annotationAdd BLAST84

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
<p>This subsection of the ‘Family and Domains’ section describes a region of interest that cannot be described in other subsections.<p><a href='/help/region' target='_top'>More...</a></p>Regioni59 – 221Interaction with KAT6A and KAT6BBy similarityAdd BLAST163
Regioni500 – 819Interaction with MEAF6 and ING5By similarityAdd BLAST320
Regioni542 – 1077Required for RUNX1 and RUNX2 transcriptional activationBy similarityAdd BLAST536

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri21 – 47C2H2-typePROSITE-ProRule annotationAdd BLAST27
Zinc fingeri272 – 322PHD-type 1PROSITE-ProRule annotationAdd BLAST51
Zinc fingeri326 – 359C2HC pre-PHD-typePROSITE-ProRule annotationAdd BLAST34
Zinc fingeri383 – 447PHD-type 2PROSITE-ProRule annotationAdd BLAST65

Keywords - Domaini

Bromodomain, Repeat, Zinc-finger

Phylogenomic databases

evolutionary genealogy of genes: Non-supervised Orthologous Groups

More...
eggNOGi
KOG0955 Eukaryota
COG5076 LUCA
COG5141 LUCA

Ensembl GeneTree

More...
GeneTreei
ENSGT00940000157794

The HOVERGEN Database of Homologous Vertebrate Genes

More...
HOVERGENi
HBG004895

KEGG Orthology (KO)

More...
KOi
K11348

Database of Orthologous Groups

More...
OrthoDBi
566217at2759

Family and domain databases

Conserved Domains Database

More...
CDDi
cd05839 BR140_related, 1 hit

Gene3D Structural and Functional Annotation of Protein Families

More...
Gene3Di
1.20.920.10, 1 hit
3.30.40.10, 2 hits

Integrated resource of protein families, domains and functional sites

More...
InterProi
View protein in InterPro
IPR035502 BR140-rel_PWWD
IPR001487 Bromodomain
IPR036427 Bromodomain-like_sf
IPR018359 Bromodomain_CS
IPR019542 Enhancer_polycomb-like_N
IPR034732 EPHD
IPR000313 PWWP_dom
IPR019786 Zinc_finger_PHD-type_CS
IPR013087 Znf_C2H2_type
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD

Pfam protein domain database

More...
Pfami
View protein in Pfam
PF00439 Bromodomain, 1 hit
PF10513 EPL1, 1 hit
PF00855 PWWP, 1 hit

Protein Motif fingerprint database; a protein domain database

More...
PRINTSi
PR00503 BROMODOMAIN

Simple Modular Architecture Research Tool; a protein domain database

More...
SMARTi
View protein in SMART
SM00297 BROMO, 1 hit
SM00249 PHD, 2 hits
SM00293 PWWP, 1 hit

Superfamily database of structural and functional annotation

More...
SUPFAMi
SSF47370 SSF47370, 1 hit
SSF57903 SSF57903, 1 hit

PROSITE; a protein domain and family database

More...
PROSITEi
View protein in PROSITE
PS00633 BROMODOMAIN_1, 1 hit
PS50014 BROMODOMAIN_2, 1 hit
PS51805 EPHD, 1 hit
PS50812 PWWP, 1 hit
PS01359 ZF_PHD_1, 1 hit
PS50016 ZF_PHD_2, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 1 hit
PS50157 ZINC_FINGER_C2H2_2, 1 hit

<p>This section displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including <a href="http://www.uniprot.org/help/sequence_length">length</a> and <a href="http://www.uniprot.org/help/sequences">molecular weight</a>.<p><a href='/help/sequences_section' target='_top'>More...</a></p>Sequence (1+)i

<p>This subsection of the <a href="http://www.uniprot.org/help/sequences_section">Sequence</a> section indicates if the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> displayed by default in the entry is complete or not.<p><a href='/help/sequence_status' target='_top'>More...</a></p>Sequence statusi: Complete.

This entry has 1 described isoform and 6 potential isoforms that are computationally mapped.Show allAlign All

B2RRD7-1 [UniParc]FASTAAdd to basket
« Hide
        10         20         30         40         50
MGVDFDVKTF CHNLRATKPP YECPVETCRK VYKSYSGIEY HLYHYDHDSP
60 70 80 90 100
PPPQQTPLRK HKKKGRQSRP ANKQSPSPSE VSQSPGREVM SYAQAQRMVE
110 120 130 140 150
VDLHGRVHRI SIFDNLDVVS EDEEAPEEAP ENGSNKENTE TPAATPKSGK
160 170 180 190 200
HKNKEKRKDS NHHHHSAPAS AAPKLPEVVY RELEQDTPDA PPRPTSYYRY
210 220 230 240 250
IEKSAEELDE EVEYDMDEED YIWLDIMNER RKTEGVSPIP QEIFEYLMDR
260 270 280 290 300
LEKESYFESH NKGDPNALVD EDAVCCICND GECQNSNVIL FCDMCNLAVH
310 320 330 340 350
QECYGVPYIP EGQWLCRRCL QSPSRAVDCA LCPNKGGAFK QTDDGRWAHV
360 370 380 390 400
VCALWIPEVC FANTVFLEPI DSIEHIPPAR WKLTCYICKQ RGSGACIQCH
410 420 430 440 450
KANCYTAFHV TCAQQAGLYM KMEPVRETGA NGTSFSVRKT AYCDIHTPPG
460 470 480 490 500
SARRLPALSH SEGEEEEDEE EDEGKSWSSE KVKKAKAKSR IKMKKARKIL
510 520 530 540 550
AEKRAAAPVV SVPCIPPHRL SKITNRLTIQ RKSQFMQRLH SYWTLKRQSR
560 570 580 590 600
NGVPLLRRLQ THLQSQRNCE QVGRDSDDKN WALKEQLKSW QRLRHDLERA
610 620 630 640 650
RLLVELIRKR EKLKRETIKI QQIAMEMQLT PFLILLRKTL EQLQEKDTGN
660 670 680 690 700
IFSEPVPLSE VPDYLDHIKK PMDFFTMKQN LEAYRYLNFD DFEEDFNLIV
710 720 730 740 750
SNCLKYNAKD TIFYRAAVRL REQGGAVLRQ ARRQAEKMGI DFETGMHIPH
760 770 780 790 800
NLAGDEVSHH TEDVEEERLV LLENQKHLPV EEQLKLLLER LDEVNASKQS
810 820 830 840 850
VGRSRRAKMI KKEMTALRRK LAHQRETGRD GPERHGPSGR GNLTPHPAAC
860 870 880 890 900
DKDGQTDSAA EESSSQETSK GLGPNMSSTP AHEVGRRTSV LFSKKNPKTA
910 920 930 940 950
GPPKRPGRPP KNRESQMTPS HGGSPVGPPQ LPIMGSLRQR KRGRSPRPSS
960 970 980 990 1000
SSDSDSDKST EDPPMDLPAN GFSSGNQPVK KSFLVYRNDC NLPRSSSDSE
1010 1020 1030 1040 1050
SSSSSSSSAA SDRTSTTPSK QGRGKPSFSR GTFPEDSSED TSGTENEAYS
1060 1070 1080 1090 1100
VGTGRGVGHS MVRKSLGRGA GWLSEDEDSP LDALDLVWAK CRGYPSYPAL
1110 1120 1130 1140 1150
IIDPKMPREG MFHHGVPIPV PPLEVLKLGE QMTQEAREHL YLVLFFDNKR
1160 1170 1180 1190 1200
TWQWLPRTKL VPLGVNQDLD KEKMLEGRKS NIRKSVQIAY HRALQHRSKV
1210
QGEQSSETSD SD
Length:1,212
Mass (Da):137,310
Last modified:July 1, 2008 - v1
<p>The checksum is a form of redundancy check that is calculated from the sequence. It is useful for tracking sequence updates.</p> <p>It should be noted that while, in theory, two different sequences could have the same checksum value, the likelihood that this would happen is extremely low.</p> <p>However UniProtKB may contain entries with identical sequences in case of multiple genes (paralogs).</p> <p>The checksum is computed as the sequence 64-bit Cyclic Redundancy Check value (CRC64) using the generator polynomial: x<sup>64</sup> + x<sup>4</sup> + x<sup>3</sup> + x + 1. The algorithm is described in the ISO 3309 standard. </p> <p class="publication">Press W.H., Flannery B.P., Teukolsky S.A. and Vetterling W.T.<br /> <strong>Cyclic redundancy and other checksums</strong><br /> <a href="http://www.nrbook.com/b/bookcpdf.php">Numerical recipes in C 2nd ed., pp896-902, Cambridge University Press (1993)</a>)</p> Checksum:i2FC14ECF8FF5DECE
GO

<p>In eukaryotic reference proteomes, unreviewed entries that are likely to belong to the same gene are computationally mapped, based on gene identifiers from Ensembl, EnsemblGenomes and model organism databases.<p><a href='/help/gene_centric_isoform_mapping' target='_top'>More...</a></p>Computationally mapped potential isoform sequencesi

There are 6 potential isoforms mapped to this entry.BLASTAlignShow allAdd to basket
EntryEntry nameProtein names
Gene namesLengthAnnotation
Q3U109Q3U109_MOUSE
Peregrin
Brpf1
1,247Annotation score:

Annotation score:2 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
Q80XK2Q80XK2_MOUSE
Bromodomain and PHD finger containi...
Brpf1
1,246Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
E9PXP1E9PXP1_MOUSE
Peregrin
Brpf1
1,219Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0N4SUT9A0A0N4SUT9_MOUSE
Peregrin
Brpf1
1,252Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0N4SVG7A0A0N4SVG7_MOUSE
Peregrin
Brpf1
1,218Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>
A0A0N4SUS4A0A0N4SUS4_MOUSE
Peregrin
Brpf1
1,118Annotation score:

Annotation score:1 out of 5

<p>The annotation score provides a heuristic measure of the annotation content of a UniProtKB entry or proteome. This score <strong>cannot</strong> be used as a measure of the accuracy of the annotation as we cannot define the ‘correct annotation’ for any given protein.<p><a href='/help/annotation_score' target='_top'>More...</a></p>

Sequence databases

Select the link destinations:

EMBL nucleotide sequence database

More...
EMBLi

GenBank nucleotide sequence database

More...
GenBanki

DNA Data Bank of Japan; a nucleotide sequence database

More...
DDBJi
Links Updated
AC155287 Genomic DNA No translation available.
CH466523 Genomic DNA Translation: EDK99448.1
BC138361 mRNA Translation: AAI38362.1

The Consensus CDS (CCDS) project

More...
CCDSi
CCDS71810.1

NCBI Reference Sequences

More...
RefSeqi
NP_001269056.1, NM_001282127.1
XP_006506851.1, XM_006506788.3

UniGene gene-oriented nucleotide sequence clusters

More...
UniGenei
Mm.356059
Mm.449928
Mm.474132

Genome annotation databases

Ensembl eukaryotic genome annotation project

More...
Ensembli
ENSMUST00000113122; ENSMUSP00000108747; ENSMUSG00000001632

Database of genes from NCBI RefSeq genomes

More...
GeneIDi
78783

KEGG: Kyoto Encyclopedia of Genes and Genomes

More...
KEGGi
mmu:78783

UCSC genome browser

More...
UCSCi
uc009dfb.1 mouse

<p>This section provides links to proteins that are similar to the protein sequence(s) described in this entry at different levels of sequence identity thresholds (100%, 90% and 50%) based on their membership in UniProt Reference Clusters (<a href="http://www.uniprot.org/help/uniref">UniRef</a>).<p><a href='/help/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsi

<p>This section is used to point to information related to entries and found in data collections other than UniProtKB.<p><a href='/help/cross_references_section' target='_top'>More...</a></p>Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AC155287 Genomic DNA No translation available.
CH466523 Genomic DNA Translation: EDK99448.1
BC138361 mRNA Translation: AAI38362.1
CCDSiCCDS71810.1
RefSeqiNP_001269056.1, NM_001282127.1
XP_006506851.1, XM_006506788.3
UniGeneiMm.356059
Mm.449928
Mm.474132

3D structure databases

ProteinModelPortaliB2RRD7
SMRiB2RRD7
ModBaseiSearch...
MobiDBiSearch...

PTM databases

iPTMnetiB2RRD7
PhosphoSitePlusiB2RRD7

Proteomic databases

jPOSTiB2RRD7
MaxQBiB2RRD7
PeptideAtlasiB2RRD7
PRIDEiB2RRD7

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsembliENSMUST00000113122; ENSMUSP00000108747; ENSMUSG00000001632
GeneIDi78783
KEGGimmu:78783
UCSCiuc009dfb.1 mouse

Organism-specific databases

Comparative Toxicogenomics Database

More...
CTDi
7862
MGIiMGI:1926033 Brpf1

Phylogenomic databases

eggNOGiKOG0955 Eukaryota
COG5076 LUCA
COG5141 LUCA
GeneTreeiENSGT00940000157794
HOVERGENiHBG004895
KOiK11348
OrthoDBi566217at2759

Enzyme and pathway databases

ReactomeiR-MMU-3214847 HATs acetylate histones
R-MMU-6804758 Regulation of TP53 Activity through Acetylation

Miscellaneous databases

ChiTaRS: a database of human, mouse and fruit fly chimeric transcripts and RNA-sequencing data

More...
ChiTaRSi
Brpf1 mouse

Protein Ontology

More...
PROi
PR:B2RRD7

The Stanford Online Universal Resource for Clones and ESTs

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SOURCEi
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Gene expression databases

BgeeiENSMUSG00000001632 Expressed in 283 organ(s), highest expression level in humerus cartilage element
ExpressionAtlasiB2RRD7 baseline and differential

Family and domain databases

CDDicd05839 BR140_related, 1 hit
Gene3Di1.20.920.10, 1 hit
3.30.40.10, 2 hits
InterProiView protein in InterPro
IPR035502 BR140-rel_PWWD
IPR001487 Bromodomain
IPR036427 Bromodomain-like_sf
IPR018359 Bromodomain_CS
IPR019542 Enhancer_polycomb-like_N
IPR034732 EPHD
IPR000313 PWWP_dom
IPR019786 Zinc_finger_PHD-type_CS
IPR013087 Znf_C2H2_type
IPR011011 Znf_FYVE_PHD
IPR001965 Znf_PHD
IPR019787 Znf_PHD-finger
IPR013083 Znf_RING/FYVE/PHD
PfamiView protein in Pfam
PF00439 Bromodomain, 1 hit
PF10513 EPL1, 1 hit
PF00855 PWWP, 1 hit
PRINTSiPR00503 BROMODOMAIN
SMARTiView protein in SMART
SM00297 BROMO, 1 hit
SM00249 PHD, 2 hits
SM00293 PWWP, 1 hit
SUPFAMiSSF47370 SSF47370, 1 hit
SSF57903 SSF57903, 1 hit
PROSITEiView protein in PROSITE
PS00633 BROMODOMAIN_1, 1 hit
PS50014 BROMODOMAIN_2, 1 hit
PS51805 EPHD, 1 hit
PS50812 PWWP, 1 hit
PS01359 ZF_PHD_1, 1 hit
PS50016 ZF_PHD_2, 1 hit
PS00028 ZINC_FINGER_C2H2_1, 1 hit
PS50157 ZINC_FINGER_C2H2_2, 1 hit

ProtoNet; Automatic hierarchical classification of proteins

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<p>This section provides general information on the entry.<p><a href='/help/entry_information_section' target='_top'>More...</a></p>Entry informationi

<p>This subsection of the ‘Entry information’ section provides a mnemonic identifier for a UniProtKB entry, but it is not a stable identifier. Each reviewed entry is assigned a unique entry name upon integration into UniProtKB/Swiss-Prot.<p><a href='/help/entry_name' target='_top'>More...</a></p>Entry nameiBRPF1_MOUSE
<p>This subsection of the ‘Entry information’ section provides one or more accession number(s). These are stable identifiers and should be used to cite UniProtKB entries. Upon integration into UniProtKB, each entry is assigned a unique accession number, which is called ‘Primary (citable) accession number’.<p><a href='/help/accession_numbers' target='_top'>More...</a></p>AccessioniPrimary (citable) accession number: B2RRD7
<p>This subsection of the ‘Entry information’ section shows the date of integration of the entry into UniProtKB, the date of the last sequence update and the date of the last annotation modification (‘Last modified’). The version number for both the entry and the <a href="http://www.uniprot.org/help/canonical_and_isoforms">canonical sequence</a> are also displayed.<p><a href='/help/entry_history' target='_top'>More...</a></p>Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 10, 2017
Last sequence update: July 1, 2008
Last modified: January 16, 2019
This is version 94 of the entry and version 1 of the sequence. See complete history.
<p>This subsection of the ‘Entry information’ section indicates whether the entry has been manually annotated and reviewed by UniProtKB curators or not, in other words, if the entry belongs to the Swiss-Prot section of UniProtKB (<strong>reviewed</strong>) or to the computer-annotated TrEMBL section (<strong>unreviewed</strong>).<p><a href='/help/entry_status' target='_top'>More...</a></p>Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programChordata Protein Annotation Program

<p>This section contains any relevant information that doesn’t fit in any other defined sections<p><a href='/help/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. MGD cross-references
    Mouse Genome Database (MGD) cross-references in UniProtKB/Swiss-Prot
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