UniProtKB - B2RCN8 (B2RCN8_HUMAN)
Protein
Submitted name:
cDNA, FLJ96179, highly similar to Homo sapiens glucocorticoid modulatory element binding protein 1 (GMEB1), transcript variant 1, mRNA
Gene
N/A
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- DNA-binding transcription activator activity, RNA polymerase II-specific Source: InterPro
- metal ion binding Source: UniProtKB-KW
- RNA polymerase II cis-regulatory region sequence-specific DNA binding Source: InterPro
Keywordsi
Biological process | Transcription, Transcription regulationARBA annotation |
Ligand | Metal-bindingARBA annotation, ZincARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: cDNA, FLJ96179, highly similar to Homo sapiens glucocorticoid modulatory element binding protein 1 (GMEB1), transcript variant 1, mRNAImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Subcellular locationi
Keywords - Cellular componenti
CytoplasmARBA annotationFamily & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 82 – 166 | SANDInterPro annotationAdd BLAST | 85 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 370 – 398 | DisorderedSequence analysisAdd BLAST | 29 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 339 – 359 | Sequence analysisAdd BLAST | 21 | |
Coiled coili | 539 – 559 | Sequence analysisAdd BLAST | 21 |
Keywords - Domaini
Coiled coilSequence analysisARBA annotationFamily and domain databases
Gene3Di | 3.10.390.10, 1 hit |
InterProi | View protein in InterPro IPR024830, GMEB1/2 IPR010919, SAND-like_dom_sf IPR000770, SAND_dom |
PANTHERi | PTHR10417, PTHR10417, 1 hit |
Pfami | View protein in Pfam PF01342, SAND, 1 hit |
SMARTi | View protein in SMART SM00258, SAND, 1 hit |
SUPFAMi | SSF63763, SSF63763, 1 hit |
PROSITEi | View protein in PROSITE PS50864, SAND, 1 hit |
i Sequence
Sequence statusi: Complete.
B2RCN8-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MANAEVSVPV GDVVVVPTEG NEGENPEDTK TQVILQLQPV QQGLFIDGHF
60 70 80 90 100
YNRIYEAGSE NNTAVVAVET HTIHKIEEGI DTGTIEANED MEIAYPITCG
110 120 130 140 150
ESKAILLWKK FVCPGINVKC VKFNDQLISP KHFVHLAGKS TLKDWKRAIR
160 170 180 190 200
LGGIMLRKMM DSGQIDFYQH DKVCSNTCRS TKFDLLISSA RAPVPGQQTS
210 220 230 240 250
VVQTPTSADG SITQIAISEE SMEEAGLEWN SALTAAVTMA TEEGVKKDSE
260 270 280 290 300
EISEDTLMFW KGIADVGLME EVVRNIQKEI EELLRGVQQR LIQAPFQVTD
310 320 330 340 350
AAVLNNVAHT FGLMDTVKKV LDNRRNQVEQ GEEQFLYTLT DLERQLEERK
360 370 380 390 400
KQGQDHRLKS QTVQNVVLMP VSTPKPPKRP RLQRPASTTV LSPSPPVQQP
410 420 430 440 450
QFTVISPITI TPVGQSFSMG NIPVATLSQG SSPVTVHTLP SGPQLFRYAT
460 470 480 490 500
VVSSAKSSSP DTVTIHPSSS LALLSSTAMQ DGSTLGNMTT MVSPVELVAM
510 520 530 540 550
ESGLTSAIQA VESTSEDGQT IIEIDPAPDP EAEDTEGKAV ILETELRTEE
560 570
KVVAEMEEHQ HQVHNVEIVV LED
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK315195 mRNA Translation: BAG37635.1 |
RefSeqi | NP_006573.2, NM_006582.3 |
Genome annotation databases
GeneIDi | 10691 |
KEGGi | hsa:10691 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK315195 mRNA Translation: BAG37635.1 |
RefSeqi | NP_006573.2, NM_006582.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | B2RCN8 |
Protocols and materials databases
DNASUi | 10691 |
Genome annotation databases
GeneIDi | 10691 |
KEGGi | hsa:10691 |
Organism-specific databases
CTDi | 10691 |
Miscellaneous databases
BioGRID-ORCSi | 10691, 15 hits in 897 CRISPR screens |
GenomeRNAii | 10691 |
Gene expression databases
Genevisiblei | B2RCN8, HS |
Family and domain databases
Gene3Di | 3.10.390.10, 1 hit |
InterProi | View protein in InterPro IPR024830, GMEB1/2 IPR010919, SAND-like_dom_sf IPR000770, SAND_dom |
PANTHERi | PTHR10417, PTHR10417, 1 hit |
Pfami | View protein in Pfam PF01342, SAND, 1 hit |
SMARTi | View protein in SMART SM00258, SAND, 1 hit |
SUPFAMi | SSF63763, SSF63763, 1 hit |
PROSITEi | View protein in PROSITE PS50864, SAND, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B2RCN8_HUMAN | |
Accessioni | B2RCN8Primary (citable) accession number: B2RCN8 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 1, 2008 |
Last sequence update: | July 1, 2008 | |
Last modified: | February 10, 2021 | |
This is version 68 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |