UniProtKB - B2RA75 (B2RA75_HUMAN)
Protein
Submitted name:
cDNA, FLJ94739, highly similar to Homo sapiens cAMP responsive element binding protein 3-like 1 (CREB3L1), mRNA
Gene
N/A
Organism
Homo sapiens (Human)
Status
Functioni
GO - Molecular functioni
- cAMP response element binding Source: InterPro
- DNA-binding transcription factor activity Source: InterPro
GO - Biological processi
- endoplasmic reticulum unfolded protein response Source: InterPro
- positive regulation of transcription by RNA polymerase II Source: InterPro
Keywordsi
Molecular function | DNA-bindingARBA annotation |
Biological process | Transcription, Transcription regulationARBA annotation |
Names & Taxonomyi
Protein namesi | Submitted name: cDNA, FLJ94739, highly similar to Homo sapiens cAMP responsive element binding protein 3-like 1 (CREB3L1), mRNAImported |
Organismi | Homo sapiens (Human)Imported |
Taxonomic identifieri | 9606 [NCBI] |
Taxonomic lineagei | Eukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo |
Family & Domainsi
Domains and Repeats
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Domaini | 290 – 353 | BZIPInterPro annotationAdd BLAST | 64 |
Region
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Regioni | 71 – 98 | DisorderedSequence analysisAdd BLAST | 28 | |
Regioni | 200 – 259 | DisorderedSequence analysisAdd BLAST | 60 | |
Regioni | 478 – 519 | DisorderedSequence analysisAdd BLAST | 42 |
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 336 – 359 | Sequence analysisAdd BLAST | 24 |
Compositional bias
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Compositional biasi | 82 – 96 | PolarSequence analysisAdd BLAST | 15 | |
Compositional biasi | 207 – 251 | PolarSequence analysisAdd BLAST | 45 |
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
OrthoDBi | 644485at2759 |
Family and domain databases
InterProi | View protein in InterPro IPR004827, bZIP IPR001630, Leuzip_CREB IPR029805, OASIS |
PANTHERi | PTHR46004:SF1, PTHR46004:SF1, 1 hit |
Pfami | View protein in Pfam PF00170, bZIP_1, 1 hit |
PRINTSi | PR00041, LEUZIPPRCREB |
SMARTi | View protein in SMART SM00338, BRLZ, 1 hit |
PROSITEi | View protein in PROSITE PS50217, BZIP, 1 hit PS00036, BZIP_BASIC, 1 hit |
i Sequence
Sequence statusi: Complete.
B2RA75-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MDAVLEPFPA DRLFPGSSFL DLGDLNESDF LNNAHFPEHL DHFTENMEDF
60 70 80 90 100
SNDLFSSFFD DPVLDEKSPL LDMELDSPTP GIQAEHSYSL SGDSAPQSPL
110 120 130 140 150
VPIKMEDTTQ DAEHGAWALG HKLCSIMVKQ EQSPELPVDP LAAPSAMAAA
160 170 180 190 200
AAMATTPLLG LSPLSRLPIP HQAPGEMTQL PVIKAEPLEV NQFLKVTPED
210 220 230 240 250
LVQMPPTPPS SHGSDSDGSQ SPRSLPPSSP VRPMARSSTA ISTSPLLTAP
260 270 280 290 300
HKLQGTSGPL LLTEEEKRTL IAEGYPIPTK LPLTKAEEKA LKRVRRKIKN
310 320 330 340 350
KISAQESRRK KKEYVECLEK KVETFTSENN ELWKKVETLE NANRTLLQQL
360 370 380 390 400
QKLQTLVTNK ISRPYKMAAT QTGTCLMVAA LCFVLVLGSL VPCLPEFSSG
410 420 430 440 450
SQTVKEDPLV ADGVYTASQM PSRSLLFYDD GAGLWEDGRS TLLPMEPPDG
460 470 480 490 500
WEINPGGPAE QRPRDHLQHD HLDSTHETTK YLSEAWPKDS GNGTSPDFSH
510
SKEWFHDRDL GPNTTIKLS
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK314072 mRNA Translation: BAG36772.1 |
RefSeqi | NP_443086.1, NM_052854.3 |
Genome annotation databases
GeneIDi | 90993 |
KEGGi | hsa:90993 |
Similar proteinsi
Cross-referencesi
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | AK314072 mRNA Translation: BAG36772.1 |
RefSeqi | NP_443086.1, NM_052854.3 |
3D structure databases
ModBasei | Search... |
SWISS-MODEL-Workspacei | Submit a new modelling project... |
Proteomic databases
PeptideAtlasi | B2RA75 |
Genome annotation databases
GeneIDi | 90993 |
KEGGi | hsa:90993 |
Organism-specific databases
CTDi | 90993 |
Phylogenomic databases
OrthoDBi | 644485at2759 |
Miscellaneous databases
BioGRID-ORCSi | 90993, 7 hits in 897 CRISPR screens |
GenomeRNAii | 90993 |
Family and domain databases
InterProi | View protein in InterPro IPR004827, bZIP IPR001630, Leuzip_CREB IPR029805, OASIS |
PANTHERi | PTHR46004:SF1, PTHR46004:SF1, 1 hit |
Pfami | View protein in Pfam PF00170, bZIP_1, 1 hit |
PRINTSi | PR00041, LEUZIPPRCREB |
SMARTi | View protein in SMART SM00338, BRLZ, 1 hit |
PROSITEi | View protein in PROSITE PS50217, BZIP, 1 hit PS00036, BZIP_BASIC, 1 hit |
ProtoNeti | Search... |
MobiDBi | Search... |
Entry informationi
Entry namei | B2RA75_HUMAN | |
Accessioni | B2RA75Primary (citable) accession number: B2RA75 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | July 1, 2008 |
Last sequence update: | July 1, 2008 | |
Last modified: | February 10, 2021 | |
This is version 76 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) | |
Disclaimer | Any medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care. |